Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Outer dynein arm docking complex protein 2, putative

Species:

Leishmania mexicana

UniProt:

E9AKY3_LEIMU

TriTrypDb:

LmxM.06.1040

Length:

722

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Cellular components
Term	Name	Level	Count
GO:0005929	cilium	4	1
GO:0042995	cell projection	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0110165	cellular anatomical entity	1	1
GO:0120025	plasma membrane bounded cell projection	3	1

Expansion

Sequence features

E9AKY3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AKY3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	371	375	PF00656	0.590
CLV_C14_Caspase3-7	403	407	PF00656	0.640
CLV_NRD_NRD_1	142	144	PF00675	0.559
CLV_NRD_NRD_1	162	164	PF00675	0.303
CLV_NRD_NRD_1	165	167	PF00675	0.486
CLV_NRD_NRD_1	251	253	PF00675	0.527
CLV_NRD_NRD_1	318	320	PF00675	0.583
CLV_NRD_NRD_1	347	349	PF00675	0.659
CLV_NRD_NRD_1	419	421	PF00675	0.594
CLV_NRD_NRD_1	44	46	PF00675	0.532
CLV_NRD_NRD_1	61	63	PF00675	0.513
CLV_NRD_NRD_1	624	626	PF00675	0.593
CLV_NRD_NRD_1	649	651	PF00675	0.681
CLV_NRD_NRD_1	709	711	PF00675	0.567
CLV_PCSK_FUR_1	140	144	PF00082	0.564
CLV_PCSK_KEX2_1	140	142	PF00082	0.569
CLV_PCSK_KEX2_1	250	252	PF00082	0.526
CLV_PCSK_KEX2_1	318	320	PF00082	0.583
CLV_PCSK_KEX2_1	346	348	PF00082	0.694
CLV_PCSK_KEX2_1	43	45	PF00082	0.537
CLV_PCSK_KEX2_1	61	63	PF00082	0.522
CLV_PCSK_KEX2_1	624	626	PF00082	0.586
CLV_PCSK_KEX2_1	649	651	PF00082	0.681
CLV_PCSK_KEX2_1	716	718	PF00082	0.625
CLV_PCSK_PC1ET2_1	250	252	PF00082	0.537
CLV_PCSK_PC1ET2_1	716	718	PF00082	0.548
CLV_PCSK_PC7_1	645	651	PF00082	0.688
CLV_PCSK_SKI1_1	167	171	PF00082	0.556
CLV_PCSK_SKI1_1	328	332	PF00082	0.540
CLV_PCSK_SKI1_1	336	340	PF00082	0.510
CLV_PCSK_SKI1_1	466	470	PF00082	0.494
CLV_PCSK_SKI1_1	480	484	PF00082	0.656
CLV_PCSK_SKI1_1	591	595	PF00082	0.616
CLV_PCSK_SKI1_1	645	649	PF00082	0.686
CLV_PCSK_SKI1_1	716	720	PF00082	0.645
DEG_APCC_DBOX_1	155	163	PF00400	0.590
DEG_APCC_DBOX_1	310	318	PF00400	0.518
DEG_APCC_DBOX_1	42	50	PF00400	0.665
DEG_APCC_DBOX_1	81	89	PF00400	0.641
DEG_SPOP_SBC_1	360	364	PF00917	0.606
DEG_SPOP_SBC_1	511	515	PF00917	0.430
DOC_CKS1_1	396	401	PF01111	0.781
DOC_PP1_RVXF_1	550	557	PF00149	0.554
DOC_PP2B_LxvP_1	8	11	PF13499	0.502
DOC_USP7_MATH_1	114	118	PF00917	0.778
DOC_USP7_MATH_1	283	287	PF00917	0.567
DOC_USP7_MATH_1	482	486	PF00917	0.762
DOC_USP7_MATH_1	518	522	PF00917	0.720
DOC_USP7_MATH_1	637	641	PF00917	0.634
DOC_WW_Pin1_4	395	400	PF00397	0.786
DOC_WW_Pin1_4	489	494	PF00397	0.717
LIG_14-3-3_CanoR_1	346	351	PF00244	0.710
LIG_14-3-3_CanoR_1	480	485	PF00244	0.731
LIG_14-3-3_CanoR_1	614	622	PF00244	0.601
LIG_14-3-3_CanoR_1	673	681	PF00244	0.722
LIG_14-3-3_CanoR_1	702	712	PF00244	0.620
LIG_APCC_ABBA_1	412	417	PF00400	0.613
LIG_APCC_ABBAyCdc20_2	445	451	PF00400	0.635
LIG_FHA_1	29	35	PF00498	0.612
LIG_FHA_1	468	474	PF00498	0.421
LIG_FHA_1	522	528	PF00498	0.483
LIG_FHA_1	549	555	PF00498	0.545
LIG_FHA_1	568	574	PF00498	0.314
LIG_FHA_1	600	606	PF00498	0.475
LIG_FHA_1	61	67	PF00498	0.581
LIG_FHA_1	704	710	PF00498	0.585
LIG_FHA_2	232	238	PF00498	0.569
LIG_FHA_2	322	328	PF00498	0.532
LIG_FHA_2	338	344	PF00498	0.533
LIG_FHA_2	360	366	PF00498	0.651
LIG_FHA_2	481	487	PF00498	0.508
LIG_FHA_2	592	598	PF00498	0.540
LIG_FHA_2	692	698	PF00498	0.694
LIG_LIR_Gen_1	290	299	PF02991	0.489
LIG_LIR_Nem_3	188	193	PF02991	0.602
LIG_LIR_Nem_3	210	215	PF02991	0.468
LIG_LIR_Nem_3	290	296	PF02991	0.495
LIG_LIR_Nem_3	416	422	PF02991	0.449
LIG_LIR_Nem_3	443	449	PF02991	0.560
LIG_MYND_1	651	655	PF01753	0.655
LIG_Rb_LxCxE_1	259	277	PF01857	0.595
LIG_SH2_CRK	190	194	PF00017	0.603
LIG_SH2_CRK	244	248	PF00017	0.509
LIG_SH2_CRK	419	423	PF00017	0.582
LIG_SH2_GRB2like	131	134	PF00017	0.575
LIG_SH2_NCK_1	289	293	PF00017	0.529
LIG_SH2_SRC	131	134	PF00017	0.575
LIG_SH2_SRC	618	621	PF00017	0.619
LIG_SH2_STAP1	244	248	PF00017	0.530
LIG_SH2_STAP1	289	293	PF00017	0.495
LIG_SH2_STAT5	256	259	PF00017	0.459
LIG_SH2_STAT5	618	621	PF00017	0.565
LIG_SH3_3	488	494	PF00018	0.754
LIG_SH3_3	8	14	PF00018	0.665
LIG_SxIP_EBH_1	678	687	PF03271	0.464
LIG_TRAF2_1	330	333	PF00917	0.572
MOD_CK1_1	232	238	PF00069	0.396
MOD_CK1_1	364	370	PF00069	0.750
MOD_CK1_1	401	407	PF00069	0.691
MOD_CK1_1	492	498	PF00069	0.599
MOD_CK1_1	521	527	PF00069	0.727
MOD_CK2_1	114	120	PF00069	0.683
MOD_CK2_1	231	237	PF00069	0.570
MOD_CK2_1	321	327	PF00069	0.528
MOD_CK2_1	337	343	PF00069	0.527
MOD_CK2_1	359	365	PF00069	0.561
MOD_CK2_1	480	486	PF00069	0.533
MOD_CK2_1	583	589	PF00069	0.531
MOD_CK2_1	591	597	PF00069	0.560
MOD_CK2_1	702	708	PF00069	0.655
MOD_CK2_1	92	98	PF00069	0.642
MOD_GlcNHglycan	177	181	PF01048	0.505
MOD_GlcNHglycan	28	31	PF01048	0.612
MOD_GlcNHglycan	370	373	PF01048	0.672
MOD_GlcNHglycan	400	403	PF01048	0.574
MOD_GlcNHglycan	422	425	PF01048	0.577
MOD_GlcNHglycan	520	523	PF01048	0.714
MOD_GlcNHglycan	524	527	PF01048	0.723
MOD_GlcNHglycan	563	567	PF01048	0.570
MOD_GSK3_1	104	111	PF00069	0.673
MOD_GSK3_1	114	121	PF00069	0.644
MOD_GSK3_1	16	23	PF00069	0.711
MOD_GSK3_1	24	31	PF00069	0.693
MOD_GSK3_1	360	367	PF00069	0.745
MOD_GSK3_1	401	408	PF00069	0.598
MOD_GSK3_1	467	474	PF00069	0.645
MOD_GSK3_1	480	487	PF00069	0.754
MOD_GSK3_1	492	499	PF00069	0.723
MOD_GSK3_1	517	524	PF00069	0.708
MOD_GSK3_1	527	534	PF00069	0.611
MOD_GSK3_1	672	679	PF00069	0.746
MOD_N-GLC_1	21	26	PF02516	0.696
MOD_N-GLC_1	358	363	PF02516	0.658
MOD_N-GLC_2	335	337	PF02516	0.595
MOD_NEK2_1	123	128	PF00069	0.605
MOD_NEK2_1	229	234	PF00069	0.598
MOD_NEK2_1	405	410	PF00069	0.472
MOD_NEK2_2	125	130	PF00069	0.722
MOD_PIKK_1	229	235	PF00454	0.595
MOD_PIKK_1	303	309	PF00454	0.542
MOD_PIKK_1	37	43	PF00454	0.631
MOD_PIKK_1	405	411	PF00454	0.548
MOD_PIKK_1	531	537	PF00454	0.664
MOD_PIKK_1	567	573	PF00454	0.338
MOD_PIKK_1	628	634	PF00454	0.655
MOD_PK_1	475	481	PF00069	0.442
MOD_PKA_1	346	352	PF00069	0.677
MOD_PKA_1	420	426	PF00069	0.588
MOD_PKA_2	157	163	PF00069	0.412
MOD_PKA_2	346	352	PF00069	0.627
MOD_PKA_2	367	373	PF00069	0.788
MOD_PKA_2	60	66	PF00069	0.612
MOD_PKA_2	613	619	PF00069	0.531
MOD_PKA_2	672	678	PF00069	0.747
MOD_Plk_1	21	27	PF00069	0.616
MOD_Plk_1	662	668	PF00069	0.724
MOD_Plk_2-3	92	98	PF00069	0.696
MOD_Plk_4	600	606	PF00069	0.545
MOD_ProDKin_1	395	401	PF00069	0.783
MOD_ProDKin_1	489	495	PF00069	0.719
MOD_SUMO_for_1	134	137	PF00179	0.646
MOD_SUMO_for_1	354	357	PF00179	0.719
MOD_SUMO_rev_2	117	124	PF00179	0.640
MOD_SUMO_rev_2	708	718	PF00179	0.600
TRG_DiLeu_BaEn_1	225	230	PF01217	0.505
TRG_DiLeu_BaEn_1	253	258	PF01217	0.445
TRG_DiLeu_BaEn_1	259	264	PF01217	0.448
TRG_DiLeu_BaEn_1	316	321	PF01217	0.541
TRG_DiLeu_BaEn_4	91	97	PF01217	0.688
TRG_DiLeu_LyEn_5	316	321	PF01217	0.563
TRG_ENDOCYTIC_2	190	193	PF00928	0.604
TRG_ENDOCYTIC_2	244	247	PF00928	0.524
TRG_ENDOCYTIC_2	419	422	PF00928	0.592
TRG_ENDOCYTIC_2	446	449	PF00928	0.508
TRG_ER_diArg_1	140	143	PF00400	0.615
TRG_ER_diArg_1	156	159	PF00400	0.393
TRG_ER_diArg_1	317	319	PF00400	0.586
TRG_ER_diArg_1	346	348	PF00400	0.663
TRG_ER_diArg_1	42	45	PF00400	0.537
TRG_ER_diArg_1	51	54	PF00400	0.525
TRG_ER_diArg_1	61	64	PF00400	0.525
TRG_ER_diArg_1	648	650	PF00400	0.688
TRG_NLS_MonoExtC_3	162	167	PF00514	0.633
TRG_Pf-PMV_PEXEL_1	150	154	PF00026	0.577
TRG_Pf-PMV_PEXEL_1	172	177	PF00026	0.542
TRG_Pf-PMV_PEXEL_1	191	196	PF00026	0.497
TRG_Pf-PMV_PEXEL_1	199	203	PF00026	0.521
TRG_Pf-PMV_PEXEL_1	241	245	PF00026	0.398
TRG_Pf-PMV_PEXEL_1	318	323	PF00026	0.531
TRG_Pf-PMV_PEXEL_1	44	48	PF00026	0.609
TRG_Pf-PMV_PEXEL_1	552	557	PF00026	0.603
TRG_Pf-PMV_PEXEL_1	64	68	PF00026	0.331
TRG_Pf-PMV_PEXEL_1	717	721	PF00026	0.694

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I4C6	Leptomonas seymouri	47%	96%
A0A1X0NL89	Trypanosomatidae	28%	100%
A0A3R7MAS7	Trypanosoma rangeli	26%	100%
A0A3S5H5T8	Leishmania donovani	88%	100%
A4H4R7	Leishmania braziliensis	65%	100%
A4HSZ6	Leishmania infantum	88%	100%
Q4QIX2	Leishmania major	85%	100%