Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AKU5_LEIMU

TriTrypDb:

LmxM.06.0660

Length:

634

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 2
Forrest at al. (procyclic)	no	yes: 2
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AKU5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AKU5

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	206	210	PF00656	0.778
CLV_C14_Caspase3-7	233	237	PF00656	0.554
CLV_NRD_NRD_1	12	14	PF00675	0.697
CLV_NRD_NRD_1	255	257	PF00675	0.715
CLV_NRD_NRD_1	258	260	PF00675	0.670
CLV_NRD_NRD_1	275	277	PF00675	0.515
CLV_NRD_NRD_1	403	405	PF00675	0.766
CLV_NRD_NRD_1	413	415	PF00675	0.689
CLV_NRD_NRD_1	99	101	PF00675	0.573
CLV_PCSK_KEX2_1	11	13	PF00082	0.847

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H5R7	Leishmania donovani	78%	93%
A4H4N1	Leishmania braziliensis	42%	97%
A4HSV7	Leishmania infantum	78%	93%
Q4QJ12	Leishmania major	73%	100%

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