Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AKU2_LEIMU

TriTrypDb:

LmxM.06.0630

Length:

306

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

E9AKU2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AKU2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	170	174	PF00656	0.661
CLV_C14_Caspase3-7	196	200	PF00656	0.670
CLV_NRD_NRD_1	148	150	PF00675	0.818
CLV_NRD_NRD_1	271	273	PF00675	0.812
CLV_NRD_NRD_1	297	299	PF00675	0.816
CLV_NRD_NRD_1	302	304	PF00675	0.752
CLV_NRD_NRD_1	39	41	PF00675	0.671
CLV_NRD_NRD_1	88	90	PF00675	0.636
CLV_PCSK_FUR_1	300	304	PF00082	0.812
CLV_PCSK_FUR_1	86	90	PF00082	0.641
CLV_PCSK_KEX2_1	148	150	PF00082	0.818
CLV_PCSK_KEX2_1	271	273	PF00082	0.812
CLV_PCSK_KEX2_1	278	280	PF00082	0.724
CLV_PCSK_KEX2_1	297	299	PF00082	0.578
CLV_PCSK_KEX2_1	302	304	PF00082	0.752
CLV_PCSK_KEX2_1	38	40	PF00082	0.677
CLV_PCSK_KEX2_1	86	88	PF00082	0.644
CLV_PCSK_PC1ET2_1	278	280	PF00082	0.812
CLV_PCSK_PC7_1	298	304	PF00082	0.812
CLV_PCSK_PC7_1	82	88	PF00082	0.654
CLV_PCSK_SKI1_1	125	129	PF00082	0.851
CLV_PCSK_SKI1_1	135	139	PF00082	0.685
CLV_PCSK_SKI1_1	275	279	PF00082	0.805
CLV_PCSK_SKI1_1	302	306	PF00082	0.819
DEG_SPOP_SBC_1	114	118	PF00917	0.650
DOC_PP1_RVXF_1	1	7	PF00149	0.855
DOC_USP7_MATH_1	115	119	PF00917	0.652
DOC_USP7_MATH_1	166	170	PF00917	0.665
DOC_USP7_MATH_1	22	26	PF00917	0.855
DOC_USP7_MATH_1	239	243	PF00917	0.617
DOC_USP7_MATH_1	34	38	PF00917	0.719
DOC_WW_Pin1_4	62	67	PF00397	0.877
DOC_WW_Pin1_4	95	100	PF00397	0.549
LIG_14-3-3_CanoR_1	10	16	PF00244	0.851
LIG_14-3-3_CanoR_1	133	142	PF00244	0.612
LIG_14-3-3_CanoR_1	231	240	PF00244	0.626
LIG_14-3-3_CanoR_1	272	278	PF00244	0.604
LIG_14-3-3_CanoR_1	58	63	PF00244	0.861
LIG_Actin_WH2_2	263	280	PF00022	0.612
LIG_BIR_III_4	199	203	PF00653	0.673
LIG_eIF4E_1	51	57	PF01652	0.860
LIG_FHA_1	228	234	PF00498	0.639
LIG_FHA_1	235	241	PF00498	0.535
LIG_FHA_1	7	13	PF00498	0.846
LIG_FHA_2	230	236	PF00498	0.632
LIG_LIR_Gen_1	14	24	PF02991	0.852
LIG_LIR_LC3C_4	98	103	PF02991	0.549
LIG_LIR_Nem_3	14	19	PF02991	0.855
LIG_LIR_Nem_3	211	217	PF02991	0.645
LIG_SH2_CRK	16	20	PF00017	0.855
LIG_SH2_NCK_1	16	20	PF00017	0.855
LIG_SH2_STAT5	16	19	PF00017	0.857
LIG_SH2_STAT5	282	285	PF00017	0.616
LIG_SH3_2	21	26	PF14604	0.854
LIG_SH3_3	15	21	PF00018	0.855
LIG_SH3_3	259	265	PF00018	0.639
LIG_SH3_3	38	44	PF00018	0.866
LIG_SH3_3	60	66	PF00018	0.871
LIG_SUMO_SIM_par_1	264	269	PF11976	0.619
LIG_TYR_ITSM	12	19	PF00017	0.837
LIG_WW_3	188	192	PF00397	0.852
MOD_CK1_1	116	122	PF00069	0.840
MOD_CK1_1	234	240	PF00069	0.793
MOD_CK1_1	65	71	PF00069	0.869
MOD_CK2_1	229	235	PF00069	0.811
MOD_Cter_Amidation	84	87	PF01082	0.829
MOD_GlcNHglycan	129	132	PF01048	0.800
MOD_GlcNHglycan	153	156	PF01048	0.825
MOD_GlcNHglycan	163	166	PF01048	0.677
MOD_GlcNHglycan	169	172	PF01048	0.569
MOD_GlcNHglycan	69	72	PF01048	0.862
MOD_GSK3_1	113	120	PF00069	0.829
MOD_GSK3_1	127	134	PF00069	0.562
MOD_GSK3_1	217	224	PF00069	0.842
MOD_GSK3_1	227	234	PF00069	0.639
MOD_GSK3_1	58	65	PF00069	0.853
MOD_NEK2_1	153	158	PF00069	0.829
MOD_NEK2_1	266	271	PF00069	0.777
MOD_NEK2_1	273	278	PF00069	0.639
MOD_NEK2_1	50	55	PF00069	0.841
MOD_NEK2_2	11	16	PF00069	0.831
MOD_NEK2_2	258	263	PF00069	0.823
MOD_NEK2_2	77	82	PF00069	0.874
MOD_PIKK_1	280	286	PF00454	0.779
MOD_PIKK_1	58	64	PF00454	0.849
MOD_PKA_2	144	150	PF00069	0.779
MOD_PKA_2	217	223	PF00069	0.842
MOD_PKA_2	57	63	PF00069	0.847
MOD_PKA_2	6	12	PF00069	0.820
MOD_PKB_1	133	141	PF00069	0.782
MOD_Plk_2-3	195	201	PF00069	0.859
MOD_Plk_4	14	20	PF00069	0.836
MOD_Plk_4	239	245	PF00069	0.789
MOD_Plk_4	52	58	PF00069	0.844
MOD_ProDKin_1	62	68	PF00069	0.869
MOD_ProDKin_1	95	101	PF00069	0.549
TRG_ENDOCYTIC_2	16	19	PF00928	0.840
TRG_ER_diArg_1	132	135	PF00400	0.797
TRG_ER_diArg_1	148	150	PF00400	0.505
TRG_ER_diArg_1	252	255	PF00400	0.804
TRG_ER_diArg_1	270	272	PF00400	0.460
TRG_ER_diArg_1	297	300	PF00400	0.781
TRG_ER_diArg_1	38	40	PF00400	0.868
TRG_ER_diArg_1	86	89	PF00400	0.820
TRG_Pf-PMV_PEXEL_1	231	235	PF00026	0.803