LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AKT2_LEIMU
TriTrypDb:
LmxM.06.0530
Length:
297

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AKT2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AKT2

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 209 211 PF00675 0.580
CLV_PCSK_KEX2_1 209 211 PF00082 0.563
CLV_PCSK_KEX2_1 96 98 PF00082 0.469
CLV_PCSK_PC1ET2_1 96 98 PF00082 0.469
CLV_PCSK_SKI1_1 167 171 PF00082 0.650
CLV_PCSK_SKI1_1 93 97 PF00082 0.536
DOC_CKS1_1 235 240 PF01111 0.405
DOC_CYCLIN_RxL_1 241 250 PF00134 0.582
DOC_PP2B_LxvP_1 35 38 PF13499 0.504
DOC_USP7_MATH_1 12 16 PF00917 0.652
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I6B6 Leptomonas seymouri 69% 98%
A0A1X0NKM4 Trypanosomatidae 42% 98%
A0A3S7WPG5 Leishmania donovani 92% 100%
A0A422NGX7 Trypanosoma rangeli 41% 100%
A4H4L9 Leishmania braziliensis 80% 100%
A4HSU5 Leishmania infantum 92% 100%
C9ZTF5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 36% 100%
Q4QJ25 Leishmania major 89% 100%
V5B7V6 Trypanosoma cruzi 43% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS