C2H2-type domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AKR9_LEIMU

TriTrypDb:

LmxM.06.0412

Length:

189

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AKR9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AKR9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	156	158	PF00675	0.586
CLV_NRD_NRD_1	29	31	PF00675	0.591
CLV_NRD_NRD_1	61	63	PF00675	0.633
CLV_NRD_NRD_1	94	96	PF00675	0.703
CLV_PCSK_FUR_1	154	158	PF00082	0.554
CLV_PCSK_KEX2_1	156	158	PF00082	0.559
CLV_PCSK_KEX2_1	29	31	PF00082	0.535
CLV_PCSK_KEX2_1	41	43	PF00082	0.542
CLV_PCSK_PC1ET2_1	41	43	PF00082	0.571
CLV_PCSK_SKI1_1	180	184	PF00082	0.516
CLV_PCSK_SKI1_1	22	26	PF00082	0.542
CLV_PCSK_SKI1_1	57	61	PF00082	0.564
DEG_SPOP_SBC_1	120	124	PF00917	0.687
DEG_SPOP_SBC_1	70	74	PF00917	0.784
DOC_MAPK_gen_1	179	186	PF00069	0.522
DOC_USP7_MATH_1	112	116	PF00917	0.748
DOC_USP7_MATH_1	120	124	PF00917	0.785
DOC_USP7_MATH_1	126	130	PF00917	0.568
DOC_USP7_MATH_1	70	74	PF00917	0.686
LIG_APCC_ABBA_1	18	23	PF00400	0.528
LIG_BIR_II_1	1	5	PF00653	0.641
LIG_FHA_1	3	9	PF00498	0.602
LIG_FHA_1	54	60	PF00498	0.583
LIG_FHA_1	85	91	PF00498	0.797
LIG_FHA_2	89	95	PF00498	0.719
LIG_SH2_STAT5	10	13	PF00017	0.522
LIG_TRAF2_1	149	152	PF00917	0.366
MOD_CK1_1	122	128	PF00069	0.744
MOD_CK1_1	173	179	PF00069	0.557
MOD_CK1_1	2	8	PF00069	0.613
MOD_CK1_1	74	80	PF00069	0.727
MOD_CK2_1	88	94	PF00069	0.717
MOD_GlcNHglycan	115	118	PF01048	0.786
MOD_GlcNHglycan	124	127	PF01048	0.742
MOD_GlcNHglycan	132	135	PF01048	0.478
MOD_GlcNHglycan	138	141	PF01048	0.522
MOD_GSK3_1	121	128	PF00069	0.775
MOD_GSK3_1	136	143	PF00069	0.464
MOD_GSK3_1	169	176	PF00069	0.535
MOD_GSK3_1	70	77	PF00069	0.691
MOD_GSK3_1	84	91	PF00069	0.719
MOD_NEK2_1	121	126	PF00069	0.682
MOD_NEK2_1	35	40	PF00069	0.733
MOD_NEK2_2	126	131	PF00069	0.697
MOD_PIKK_1	35	41	PF00454	0.727
MOD_PIKK_1	71	77	PF00454	0.712
MOD_PKA_2	130	136	PF00069	0.473
MOD_PKA_2	53	59	PF00069	0.689
MOD_PKA_2	88	94	PF00069	0.705
MOD_Plk_4	170	176	PF00069	0.633
MOD_SUMO_rev_2	172	182	PF00179	0.528
TRG_DiLeu_BaEn_1	55	60	PF01217	0.584
TRG_ER_diArg_1	154	157	PF00400	0.558

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1II80	Leptomonas seymouri	52%	92%
A0A3S5H5Q2	Leishmania donovani	91%	100%
A4H4K6	Leishmania braziliensis	79%	100%
A4HST2	Leishmania infantum	91%	100%
Q4QJ38	Leishmania major	90%	100%