Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AKQ0_LEIMU

TriTrypDb:

LmxM.06.0220

Length:

286

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

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Cellular components
Term	Name	Level	Count
GO:0005930	axoneme	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

E9AKQ0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AKQ0

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	54	58	PF00656	0.272
CLV_NRD_NRD_1	109	111	PF00675	0.400
CLV_NRD_NRD_1	118	120	PF00675	0.404
CLV_NRD_NRD_1	24	26	PF00675	0.553
CLV_PCSK_KEX2_1	109	111	PF00082	0.408
CLV_PCSK_SKI1_1	17	21	PF00082	0.575
CLV_PCSK_SKI1_1	252	256	PF00082	0.583
CLV_PCSK_SKI1_1	272	276	PF00082	0.694
CLV_PCSK_SKI1_1	56	60	PF00082	0.411
DEG_APCC_DBOX_1	55	63	PF00400	0.431

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBY2	Leptomonas seymouri	59%	97%
A0A0S4KGV5	Bodo saltans	31%	100%
A0A1X0NK20	Trypanosomatidae	32%	90%
A0A3R7M8M9	Trypanosoma rangeli	38%	100%
A0A3S7WPB5	Leishmania donovani	89%	100%
A4H4I8	Leishmania braziliensis	74%	100%
A4HSR3	Leishmania infantum	88%	100%
C9ZTB1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
Q4QJ57	Leishmania major	86%	100%
V5B5T8	Trypanosoma cruzi	37%	100%

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