Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AKK9_LEIMU

TriTrypDb:

LmxM.05.1030

Length:

145


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	8
GO:0110165	cellular anatomical entity	1	8

E9AKK9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AKK9


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	11	13	PF00675	0.647
CLV_NRD_NRD_1	129	131	PF00675	0.332
CLV_PCSK_KEX2_1	11	13	PF00082	0.647
DEG_Nend_UBRbox_3	1	3	PF02207	0.444
DOC_MAPK_gen_1	130	138	PF00069	0.547
DOC_PP2B_LxvP_1	94	97	PF13499	0.397
DOC_USP7_MATH_1	56	60	PF00917	0.441
DOC_USP7_UBL2_3	63	67	PF12436	0.502
DOC_WW_Pin1_4	103	108	PF00397	0.150
DOC_WW_Pin1_4	83	88	PF00397	0.473
LIG_14-3-3_CanoR_1	57	61	PF00244	0.485
LIG_FHA_1	133	139	PF00498	0.570
LIG_FHA_1	17	23	PF00498	0.381
LIG_LIR_Gen_1	106	117	PF02991	0.289
LIG_LIR_Nem_3	106	112	PF02991	0.282
LIG_LIR_Nem_3	76	82	PF02991	0.413
LIG_Pex14_1	120	124	PF04695	0.271
LIG_SH2_CRK	109	113	PF00017	0.289
LIG_SH2_STAP1	133	137	PF00017	0.561
LIG_SH2_STAT5	109	112	PF00017	0.271
LIG_SH2_STAT5	128	131	PF00017	0.541
LIG_SUMO_SIM_par_1	101	106	PF11976	0.236
LIG_WRC_WIRS_1	82	87	PF05994	0.393
MOD_CK2_1	55	61	PF00069	0.505
MOD_GlcNHglycan	13	16	PF01048	0.623
MOD_GlcNHglycan	64	67	PF01048	0.624
MOD_GlcNHglycan	90	93	PF01048	0.625
MOD_GSK3_1	7	14	PF00069	0.405
MOD_NEK2_1	1	6	PF00069	0.474
MOD_NEK2_1	16	21	PF00069	0.379
MOD_NEK2_1	43	48	PF00069	0.435
MOD_PIKK_1	23	29	PF00454	0.480
MOD_PKA_1	11	17	PF00069	0.393
MOD_PKA_2	11	17	PF00069	0.393
MOD_PKA_2	56	62	PF00069	0.389
MOD_Plk_4	1	7	PF00069	0.550
MOD_Plk_4	132	138	PF00069	0.556
MOD_Plk_4	16	22	PF00069	0.430
MOD_ProDKin_1	103	109	PF00069	0.150
MOD_ProDKin_1	83	89	PF00069	0.470
MOD_SUMO_rev_2	58	65	PF00179	0.444
TRG_ENDOCYTIC_2	109	112	PF00928	0.284
TRG_ENDOCYTIC_2	124	127	PF00928	0.475
TRG_ENDOCYTIC_2	133	136	PF00928	0.591
TRG_ENDOCYTIC_2	82	85	PF00928	0.382


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCY8	Leptomonas seymouri	70%	100%
A0A1X0NKT0	Trypanosomatidae	53%	99%
A0A3R7K2B2	Trypanosoma rangeli	58%	100%
A0A3S5H5L3	Leishmania donovani	96%	100%
A4H4E8	Leishmania braziliensis	82%	100%
A4HSM5	Leishmania infantum	96%	100%
C9ZND7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	52%	100%
Q4QJ99	Leishmania major	92%	100%
V5BBW2	Trypanosoma cruzi	51%	100%