LeishMANIAdb
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RING-type domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
RING-type domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AKK6_LEIMU
TriTrypDb:
LmxM.05.1000
Length:
103

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AKK6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AKK6

Putative motif mimicry

Leishmania From To Domain/Motif Score
DEG_Nend_UBRbox_2 1 3 PF02207 0.648
DOC_CYCLIN_yCln2_LP_2 41 44 PF00134 0.536
DOC_PP2B_LxvP_1 41 44 PF13499 0.601
DOC_PP2B_LxvP_1 60 63 PF13499 0.405
LIG_CtBP_PxDLS_1 43 47 PF00389 0.551
LIG_FHA_1 35 41 PF00498 0.554
LIG_Pex14_2 68 72 PF04695 0.361
LIG_SH3_3 37 43 PF00018 0.531
MOD_GlcNHglycan 63 66 PF01048 0.308
MOD_GlcNHglycan 9 12 PF01048 0.599
MOD_N-GLC_1 44 49 PF02516 0.542
MOD_Plk_1 44 50 PF00069 0.544

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HVG8 Leptomonas seymouri 77% 97%
A0A3S7WP79 Leishmania donovani 90% 100%
A4H4E5 Leishmania braziliensis 76% 100%
A4HSM2 Leishmania infantum 89% 100%
Q4QJA2 Leishmania major 88% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS