Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AKJ7_LEIMU

TriTrypDb:

LmxM.05.0910

Length:

1056

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	3
GO:0110165	cellular anatomical entity	1	3

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Expansion

Sequence features

E9AKJ7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AKJ7

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	106	110	PF00656	0.412
CLV_C14_Caspase3-7	160	164	PF00656	0.517
CLV_C14_Caspase3-7	317	321	PF00656	0.511
CLV_C14_Caspase3-7	400	404	PF00656	0.630
CLV_C14_Caspase3-7	501	505	PF00656	0.734
CLV_NRD_NRD_1	1032	1034	PF00675	0.675
CLV_NRD_NRD_1	120	122	PF00675	0.699
CLV_NRD_NRD_1	251	253	PF00675	0.554
CLV_NRD_NRD_1	428	430	PF00675	0.443
CLV_NRD_NRD_1	444	446	PF00675	0.436

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3E4	Leptomonas seymouri	48%	91%
A0A3S7WP72	Leishmania donovani	85%	96%
A4H4D3	Leishmania braziliensis	68%	99%
A4HSL3	Leishmania infantum	85%	96%
Q4QJB1	Leishmania major	85%	100%

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