Vesicle transport protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Got1/Sft2-like family, putative

Species:

Leishmania mexicana

UniProt:

E9AKI7_LEIMU

TriTrypDb:

LmxM.05.0810

Length:

163

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	13
GO:0110165	cellular anatomical entity	1	13

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Expansion

Sequence features

E9AKI7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AKI7

Function

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Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	13
GO:0008104	protein localization	4	13
GO:0009987	cellular process	1	13
GO:0015031	protein transport	4	13
GO:0016192	vesicle-mediated transport	4	13
GO:0033036	macromolecule localization	2	13
GO:0045184	establishment of protein localization	3	13
GO:0051179	localization	1	13
GO:0051234	establishment of localization	2	13
GO:0051641	cellular localization	2	13

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Could not find GO molecular_function term for this entry.

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	20	24	PF00656	0.675
CLV_PCSK_SKI1_1	100	104	PF00082	0.314
CLV_PCSK_SKI1_1	154	158	PF00082	0.425
CLV_PCSK_SKI1_1	90	94	PF00082	0.243
DEG_APCC_DBOX_1	121	129	PF00400	0.118
DEG_Nend_UBRbox_2	1	3	PF02207	0.633
DOC_MAPK_MEF2A_6	122	130	PF00069	0.195
DOC_PP4_FxxP_1	51	54	PF00568	0.126
LIG_14-3-3_CanoR_1	100	109	PF00244	0.263
LIG_Actin_WH2_2	106	124	PF00022	0.126

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8A7	Leptomonas seymouri	33%	100%
A0A0N1I3M5	Leptomonas seymouri	43%	92%
A0A0N1I5N1	Leptomonas seymouri	62%	97%
A0A0S4JF33	Bodo saltans	35%	100%
A0A0S4JFY8	Bodo saltans	46%	100%
A0A1X0NLN3	Trypanosomatidae	51%	96%
A0A1X0P315	Trypanosomatidae	44%	96%
A0A1X0P7F6	Trypanosomatidae	31%	100%
A0A1X0P987	Trypanosomatidae	30%	78%
A0A3Q8IBK0	Leishmania donovani	31%	100%

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