Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AKC0_LEIMU

TriTrypDb:

LmxM.05.0160

Length:

511

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AKC0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AKC0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	106	108	PF00675	0.737
CLV_NRD_NRD_1	222	224	PF00675	0.665
CLV_NRD_NRD_1	267	269	PF00675	0.668
CLV_NRD_NRD_1	433	435	PF00675	0.690
CLV_PCSK_KEX2_1	105	107	PF00082	0.720
CLV_PCSK_KEX2_1	222	224	PF00082	0.665
CLV_PCSK_KEX2_1	267	269	PF00082	0.566
CLV_PCSK_KEX2_1	433	435	PF00082	0.690
CLV_PCSK_SKI1_1	17	21	PF00082	0.579
CLV_PCSK_SKI1_1	434	438	PF00082	0.691
CLV_PCSK_SKI1_1	67	71	PF00082	0.588
DEG_SPOP_SBC_1	229	233	PF00917	0.647
DOC_MAPK_gen_1	441	448	PF00069	0.599
DOC_MAPK_MEF2A_6	441	448	PF00069	0.552
DOC_PP1_RVXF_1	280	287	PF00149	0.543
DOC_USP7_MATH_1	182	186	PF00917	0.643
DOC_USP7_MATH_1	236	240	PF00917	0.761
DOC_USP7_MATH_1	330	334	PF00917	0.616
DOC_USP7_MATH_1	424	428	PF00917	0.593
DOC_USP7_MATH_1	498	502	PF00917	0.751
DOC_WW_Pin1_4	180	185	PF00397	0.758
DOC_WW_Pin1_4	186	191	PF00397	0.660
DOC_WW_Pin1_4	225	230	PF00397	0.713
DOC_WW_Pin1_4	250	255	PF00397	0.727
DOC_WW_Pin1_4	466	471	PF00397	0.664
DOC_WW_Pin1_4	489	494	PF00397	0.785
LIG_14-3-3_CanoR_1	151	156	PF00244	0.712
LIG_14-3-3_CanoR_1	261	269	PF00244	0.441
LIG_14-3-3_CanoR_1	282	287	PF00244	0.431
LIG_14-3-3_CanoR_1	392	399	PF00244	0.462
LIG_14-3-3_CanoR_1	67	74	PF00244	0.477
LIG_APCC_ABBAyCdc20_2	5	11	PF00400	0.716
LIG_DLG_GKlike_1	282	289	PF00625	0.436
LIG_eIF4E_1	198	204	PF01652	0.584
LIG_FHA_2	298	304	PF00498	0.675
LIG_FHA_2	309	315	PF00498	0.418
LIG_FHA_2	381	387	PF00498	0.591
LIG_FHA_2	58	64	PF00498	0.563
LIG_FHA_2	94	100	PF00498	0.588
LIG_FXI_DFP_1	270	274	PF00024	0.388
LIG_LIR_Gen_1	272	279	PF02991	0.439
LIG_LIR_Gen_1	285	291	PF02991	0.547
LIG_LIR_Nem_3	212	217	PF02991	0.653
LIG_LIR_Nem_3	272	276	PF02991	0.447
LIG_LIR_Nem_3	285	289	PF02991	0.551
LIG_SH2_STAP1	406	410	PF00017	0.550
LIG_SH2_STAP1	505	509	PF00017	0.717
LIG_SH3_1	223	229	PF00018	0.690
LIG_SH3_2	164	169	PF14604	0.752
LIG_SH3_3	161	167	PF00018	0.788
LIG_SH3_3	223	229	PF00018	0.740
LIG_SH3_3	492	498	PF00018	0.722
LIG_Sin3_3	315	322	PF02671	0.470
LIG_SUMO_SIM_anti_2	285	291	PF11976	0.649
LIG_TRAF2_1	243	246	PF00917	0.753
LIG_TRAF2_1	300	303	PF00917	0.675
LIG_TRAF2_1	383	386	PF00917	0.629
LIG_WRC_WIRS_1	152	157	PF05994	0.536
LIG_WRC_WIRS_1	283	288	PF05994	0.545
MOD_CK1_1	112	118	PF00069	0.689
MOD_CK1_1	154	160	PF00069	0.678
MOD_CK1_1	180	186	PF00069	0.747
MOD_CK1_1	228	234	PF00069	0.816
MOD_CK1_1	253	259	PF00069	0.620
MOD_CK1_1	422	428	PF00069	0.489
MOD_CK1_1	461	467	PF00069	0.695
MOD_CK1_1	469	475	PF00069	0.656
MOD_CK1_1	489	495	PF00069	0.781
MOD_CK1_1	503	509	PF00069	0.694
MOD_CK2_1	297	303	PF00069	0.670
MOD_CK2_1	308	314	PF00069	0.616
MOD_CK2_1	380	386	PF00069	0.591
MOD_CK2_1	57	63	PF00069	0.657
MOD_GlcNHglycan	120	123	PF01048	0.737
MOD_GlcNHglycan	157	160	PF01048	0.832
MOD_GlcNHglycan	184	187	PF01048	0.630
MOD_GlcNHglycan	192	195	PF01048	0.645
MOD_GlcNHglycan	250	253	PF01048	0.713
MOD_GlcNHglycan	332	335	PF01048	0.538
MOD_GlcNHglycan	421	424	PF01048	0.599
MOD_GlcNHglycan	453	456	PF01048	0.496
MOD_GlcNHglycan	471	474	PF01048	0.785
MOD_GlcNHglycan	476	479	PF01048	0.689
MOD_GlcNHglycan	488	491	PF01048	0.639
MOD_GlcNHglycan	502	505	PF01048	0.683
MOD_GSK3_1	151	158	PF00069	0.626
MOD_GSK3_1	182	189	PF00069	0.724
MOD_GSK3_1	225	232	PF00069	0.689
MOD_GSK3_1	278	285	PF00069	0.652
MOD_GSK3_1	341	348	PF00069	0.583
MOD_GSK3_1	376	383	PF00069	0.621
MOD_GSK3_1	387	394	PF00069	0.542
MOD_GSK3_1	457	464	PF00069	0.625
MOD_GSK3_1	465	472	PF00069	0.671
MOD_GSK3_1	489	496	PF00069	0.708
MOD_GSK3_1	499	506	PF00069	0.686
MOD_N-GLC_1	123	128	PF02516	0.834
MOD_N-GLC_1	355	360	PF02516	0.664
MOD_N-GLC_1	451	456	PF02516	0.561
MOD_NEK2_1	146	151	PF00069	0.671
MOD_NEK2_1	155	160	PF00069	0.557
MOD_NEK2_1	204	209	PF00069	0.585
MOD_NEK2_1	248	253	PF00069	0.753
MOD_NEK2_1	343	348	PF00069	0.544
MOD_NEK2_1	388	393	PF00069	0.563
MOD_NEK2_1	437	442	PF00069	0.519
MOD_NEK2_1	458	463	PF00069	0.668
MOD_NEK2_1	465	470	PF00069	0.726
MOD_NEK2_1	474	479	PF00069	0.718
MOD_NEK2_2	308	313	PF00069	0.647
MOD_PIKK_1	146	152	PF00454	0.719
MOD_PIKK_1	204	210	PF00454	0.575
MOD_PIKK_1	260	266	PF00454	0.397
MOD_PIKK_1	292	298	PF00454	0.439
MOD_PIKK_1	343	349	PF00454	0.353
MOD_PIKK_1	391	397	PF00454	0.542
MOD_PKA_2	260	266	PF00069	0.549
MOD_PKA_2	324	330	PF00069	0.661
MOD_PKA_2	391	397	PF00069	0.542
MOD_PKB_1	107	115	PF00069	0.507
MOD_ProDKin_1	180	186	PF00069	0.756
MOD_ProDKin_1	225	231	PF00069	0.717
MOD_ProDKin_1	250	256	PF00069	0.721
MOD_ProDKin_1	466	472	PF00069	0.664
MOD_ProDKin_1	489	495	PF00069	0.781
MOD_SUMO_rev_2	54	62	PF00179	0.605
TRG_DiLeu_BaLyEn_6	279	284	PF01217	0.467
TRG_ER_diArg_1	105	107	PF00400	0.637
TRG_ER_diArg_1	221	223	PF00400	0.658
TRG_ER_diArg_1	266	268	PF00400	0.688
TRG_ER_diArg_1	432	434	PF00400	0.684
TRG_Pf-PMV_PEXEL_1	267	272	PF00026	0.479
TRG_Pf-PMV_PEXEL_1	299	303	PF00026	0.572
TRG_Pf-PMV_PEXEL_1	67	71	PF00026	0.687
TRG_Pf-PMV_PEXEL_1	95	99	PF00026	0.648

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKE8	Leptomonas seymouri	40%	97%
A0A3S7WNZ9	Leishmania donovani	83%	100%
A4H462	Leishmania braziliensis	72%	100%
A4HSD1	Leishmania infantum	83%	100%
Q4QJI7	Leishmania major	83%	100%