Putative small GTP-binding protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

small GTP-binding protein, putative

Species:

Leishmania mexicana

UniProt:

E9AKA7_LEIMU

TriTrypDb:

LmxM.05.0030

Length:

195

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005783	endoplasmic reticulum	5	10
GO:0005794	Golgi apparatus	5	11
GO:0043226	organelle	2	11
GO:0043227	membrane-bounded organelle	3	11
GO:0043229	intracellular organelle	3	11
GO:0043231	intracellular membrane-bounded organelle	4	11
GO:0110165	cellular anatomical entity	1	11
GO:0030117	membrane coat	3	1
GO:0030120	vesicle coat	4	1
GO:0030127	COPII vesicle coat	5	1
GO:0032991	protein-containing complex	1	1
GO:0070971	endoplasmic reticulum exit site	2	1
GO:0098796	membrane protein complex	2	1

Expansion

Sequence features

E9AKA7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AKA7

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	11
GO:0006886	intracellular protein transport	4	11
GO:0008104	protein localization	4	11
GO:0009987	cellular process	1	11
GO:0015031	protein transport	4	11
GO:0016192	vesicle-mediated transport	4	11
GO:0033036	macromolecule localization	2	11
GO:0045184	establishment of protein localization	3	11
GO:0046907	intracellular transport	3	11
GO:0051179	localization	1	11
GO:0051234	establishment of localization	2	11
GO:0051641	cellular localization	2	11
GO:0051649	establishment of localization in cell	3	11
GO:0070727	cellular macromolecule localization	3	11
GO:0071702	organic substance transport	4	11
GO:0071705	nitrogen compound transport	4	11
GO:0003400	regulation of COPII vesicle coating	6	1
GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	4	1
GO:0006996	organelle organization	4	1
GO:0016043	cellular component organization	3	1
GO:0016050	vesicle organization	5	1
GO:0032386	regulation of intracellular transport	5	1
GO:0032388	positive regulation of intracellular transport	5	1
GO:0032879	regulation of localization	3	1
GO:0032880	regulation of protein localization	5	1
GO:0033043	regulation of organelle organization	5	1
GO:0033157	regulation of intracellular protein transport	6	1
GO:0043254	regulation of protein-containing complex assembly	5	1
GO:0044087	regulation of cellular component biogenesis	4	1
GO:0048193	Golgi vesicle transport	5	1
GO:0048518	positive regulation of biological process	3	1
GO:0048522	positive regulation of cellular process	4	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0051049	regulation of transport	4	1
GO:0051050	positive regulation of transport	4	1
GO:0051128	regulation of cellular component organization	4	1
GO:0051222	positive regulation of protein transport	5	1
GO:0051223	regulation of protein transport	5	1
GO:0060341	regulation of cellular localization	4	1
GO:0061024	membrane organization	4	1
GO:0065007	biological regulation	1	1
GO:0070201	regulation of establishment of protein localization	6	1
GO:0070861	regulation of protein exit from endoplasmic reticulum	7	1
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	7	1
GO:0071840	cellular component organization or biogenesis	2	1
GO:0090316	positive regulation of intracellular protein transport	6	1
GO:1903829	positive regulation of protein localization	5	1
GO:1904951	positive regulation of establishment of protein localization	6	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	11
GO:0003824	catalytic activity	1	11
GO:0003924	GTPase activity	7	11
GO:0005488	binding	1	11
GO:0005525	GTP binding	5	11
GO:0016462	pyrophosphatase activity	5	11
GO:0016787	hydrolase activity	2	11
GO:0016817	hydrolase activity, acting on acid anhydrides	3	11
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	11
GO:0017076	purine nucleotide binding	4	11
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	11
GO:0019001	guanyl nucleotide binding	5	11
GO:0032553	ribonucleotide binding	3	11
GO:0032555	purine ribonucleotide binding	4	11
GO:0032561	guanyl ribonucleotide binding	5	11
GO:0035639	purine ribonucleoside triphosphate binding	4	11
GO:0036094	small molecule binding	2	11
GO:0043167	ion binding	2	11
GO:0043168	anion binding	3	11
GO:0097159	organic cyclic compound binding	2	11
GO:0097367	carbohydrate derivative binding	2	11
GO:1901265	nucleoside phosphate binding	3	11
GO:1901363	heterocyclic compound binding	2	11

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	86	90	PF00656	0.359
CLV_NRD_NRD_1	78	80	PF00675	0.359
CLV_PCSK_KEX2_1	78	80	PF00082	0.359
CLV_PCSK_SKI1_1	22	26	PF00082	0.353
CLV_PCSK_SKI1_1	39	43	PF00082	0.286
DEG_MDM2_SWIB_1	4	11	PF02201	0.575
DOC_CYCLIN_RxL_1	19	29	PF00134	0.359
DOC_MAPK_gen_1	19	28	PF00069	0.359
DOC_MAPK_HePTP_8	16	28	PF00069	0.402
DOC_MAPK_MEF2A_6	19	28	PF00069	0.359
DOC_PP1_RVXF_1	20	26	PF00149	0.359
DOC_WW_Pin1_4	119	124	PF00397	0.359
DOC_WW_Pin1_4	155	160	PF00397	0.472
DOC_WW_Pin1_4	96	101	PF00397	0.471
LIG_FHA_1	120	126	PF00498	0.471
LIG_FHA_1	18	24	PF00498	0.359
LIG_FHA_1	32	38	PF00498	0.359
LIG_FHA_1	40	46	PF00498	0.350
LIG_FHA_2	135	141	PF00498	0.471
LIG_FHA_2	84	90	PF00498	0.359
LIG_LIR_Gen_1	122	131	PF02991	0.344
LIG_LIR_Gen_1	5	16	PF02991	0.400
LIG_LIR_Gen_1	83	93	PF02991	0.359
LIG_LIR_Nem_3	12	16	PF02991	0.327
LIG_LIR_Nem_3	122	127	PF02991	0.344
LIG_LIR_Nem_3	183	188	PF02991	0.344
LIG_LIR_Nem_3	5	11	PF02991	0.526
LIG_LIR_Nem_3	83	88	PF02991	0.359
LIG_NRBOX	109	115	PF00104	0.359
LIG_Pex14_1	187	191	PF04695	0.359
LIG_Pex14_1	81	85	PF04695	0.359
LIG_Pex14_2	4	8	PF04695	0.517
LIG_PTB_Apo_2	175	182	PF02174	0.471
LIG_PTB_Phospho_1	175	181	PF10480	0.471
LIG_SH2_STAT5	13	16	PF00017	0.402
LIG_SH2_STAT5	191	194	PF00017	0.582
LIG_SH2_STAT5	84	87	PF00017	0.351
LIG_SH3_3	157	163	PF00018	0.432
LIG_SH3_3	44	50	PF00018	0.367
LIG_TYR_ITIM	11	16	PF00017	0.471
LIG_UBA3_1	24	33	PF00899	0.359
MOD_CDK_SPxK_1	96	102	PF00069	0.471
MOD_CK1_1	17	23	PF00069	0.402
MOD_CK2_1	134	140	PF00069	0.471
MOD_CMANNOS	3	6	PF00535	0.577
MOD_GSK3_1	151	158	PF00069	0.371
MOD_GSK3_1	53	60	PF00069	0.498
MOD_N-GLC_1	17	22	PF02516	0.359
MOD_NEK2_1	14	19	PF00069	0.379
MOD_NEK2_1	149	154	PF00069	0.219
MOD_PIKK_1	186	192	PF00454	0.336
MOD_PKA_2	48	54	PF00069	0.359
MOD_Plk_1	57	63	PF00069	0.359
MOD_Plk_2-3	105	111	PF00069	0.504
MOD_Plk_4	171	177	PF00069	0.343
MOD_Plk_4	32	38	PF00069	0.359
MOD_Plk_4	9	15	PF00069	0.379
MOD_ProDKin_1	119	125	PF00069	0.359
MOD_ProDKin_1	155	161	PF00069	0.472
MOD_ProDKin_1	96	102	PF00069	0.471
MOD_SUMO_for_1	106	109	PF00179	0.359
TRG_DiLeu_BaEn_1	109	114	PF01217	0.359
TRG_ENDOCYTIC_2	13	16	PF00928	0.379
TRG_ER_diArg_1	78	80	PF00400	0.359
TRG_Pf-PMV_PEXEL_1	186	190	PF00026	0.336
TRG_Pf-PMV_PEXEL_1	78	83	PF00026	0.344

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3Q3	Leptomonas seymouri	31%	100%
A0A0N0P4P7	Leptomonas seymouri	30%	100%
A0A0N0P633	Leptomonas seymouri	33%	100%
A0A0N0P8D4	Leptomonas seymouri	34%	100%
A0A0N0P8Z3	Leptomonas seymouri	34%	100%
A0A0N1HS40	Leptomonas seymouri	40%	100%
A0A0N1HTN6	Leptomonas seymouri	31%	100%
A0A0N1I3A9	Leptomonas seymouri	30%	100%
A0A0N1I556	Leptomonas seymouri	33%	100%
A0A0N1I6N0	Leptomonas seymouri	32%	100%
A0A0N1IKF2	Leptomonas seymouri	95%	100%
A0A0S4IQT8	Bodo saltans	28%	100%
A0A0S4J2X3	Bodo saltans	35%	100%
A0A0S4J5U8	Bodo saltans	29%	100%
A0A0S4J8H6	Bodo saltans	32%	100%
A0A0S4JK65	Bodo saltans	34%	100%
A0A0S4JQ13	Bodo saltans	79%	100%
A0A0S4JWF1	Bodo saltans	23%	69%
A0A0S4KJ70	Bodo saltans	31%	92%
A0A0S4KKS9	Bodo saltans	31%	100%
A0A1X0NKM5	Trypanosomatidae	31%	100%
A0A1X0NKZ8	Trypanosomatidae	36%	100%
A0A1X0NLB1	Trypanosomatidae	34%	100%
A0A1X0NT19	Trypanosomatidae	31%	100%
A0A1X0NZX3	Trypanosomatidae	32%	100%
A0A1X0P0D4	Trypanosomatidae	27%	100%
A0A1X0P1Y5	Trypanosomatidae	29%	100%
A0A1X0P2L5	Trypanosomatidae	81%	100%
A0A1X0P5P0	Trypanosomatidae	30%	100%
A0A1X0P676	Trypanosomatidae	31%	100%
A0A1X0P850	Trypanosomatidae	26%	71%
A0A221LG87	Leishmania donovani	99%	100%
A0A3Q8IDS2	Leishmania donovani	27%	100%
A0A3Q8IFX9	Leishmania donovani	30%	100%
A0A3R7L2X6	Trypanosoma rangeli	28%	100%
A0A3R7MW79	Trypanosoma rangeli	34%	100%
A0A3R7NC73	Trypanosoma rangeli	32%	100%
A0A3R7NMH3	Trypanosoma rangeli	31%	100%
A0A3R7RGT1	Trypanosoma rangeli	30%	100%
A0A3S5H598	Leishmania donovani	41%	100%
A0A3S5IQP0	Trypanosoma rangeli	31%	100%
A0A3S5ISB1	Trypanosoma rangeli	78%	100%
A0A3S7WU76	Leishmania donovani	31%	100%
A0A3S7X4X3	Leishmania donovani	32%	100%
A0A3S7X8N3	Leishmania donovani	35%	100%
A0A3S7XC57	Leishmania donovani	33%	100%
A0A422MYB1	Trypanosoma rangeli	29%	100%
A0A422MZM4	Trypanosoma rangeli	30%	100%
A0A422NNC6	Trypanosoma rangeli	38%	100%
A0A422NW53	Trypanosoma rangeli	28%	100%
A1CRG9	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	59%	100%
A1D4D1	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	59%	100%
A3LTA2	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	58%	100%
A4H3V3	Leishmania braziliensis	37%	100%
A4H3W8	Leishmania braziliensis	33%	100%
A4H449	Leishmania braziliensis	96%	100%
A4H8R6	Leishmania braziliensis	28%	99%
A4H8V3	Leishmania braziliensis	35%	100%
A4HH98	Leishmania braziliensis	32%	97%
A4HJL1	Leishmania braziliensis	33%	100%
A4HJR7	Leishmania braziliensis	33%	96%
A4HM52	Leishmania braziliensis	36%	100%
A4HNU2	Leishmania braziliensis	30%	68%
A4HQE3	Leishmania braziliensis	34%	95%
A4HS29	Leishmania infantum	41%	100%
A4HSC6	Leishmania infantum	99%	100%
A4HX34	Leishmania infantum	27%	100%
A4HX72	Leishmania infantum	31%	100%
A4I4E4	Leishmania infantum	32%	100%
A4I5R5	Leishmania infantum	30%	100%
A4I784	Leishmania infantum	32%	100%
A4IAR4	Leishmania infantum	35%	100%
A4IE34	Leishmania infantum	33%	100%
A5DR82	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	53%	100%
A5E5G3	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	56%	100%
A8ISN6	Chlamydomonas reinhardtii	31%	100%
B5FYQ0	Taeniopygia guttata	33%	100%
C9ZL19	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
C9ZPY6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	79%	100%
C9ZR33	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
C9ZTU8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
C9ZVV9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	100%
C9ZY21	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
C9ZY41	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	100%
C9ZZD4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	100%
C9ZZD6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	100%
D0A2E8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
D0A2Q7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	72%
D0A3V1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	71%
E9ADU4	Leishmania major	32%	98%
E9AEJ0	Leishmania major	35%	100%
E9AHL7	Leishmania infantum	32%	100%
E9AIU0	Leishmania braziliensis	30%	100%
E9AK16	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
E9ALY6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
E9AQU9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9ARC9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9AU58	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9B110	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9B229	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9B278	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9B5Q1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
F4IZ82	Arabidopsis thaliana	36%	100%
O00909	Dictyostelium discoideum	32%	100%
O04266	Brassica campestris	57%	100%
O04267	Brassica campestris	55%	100%
O04834	Arabidopsis thaliana	56%	100%
O23778	Catharanthus roseus	30%	100%
O45379	Caenorhabditis elegans	34%	100%
O48649	Salix bakko	31%	100%
O48920	Vigna unguiculata	30%	100%
O88848	Mus musculus	28%	100%
P0C583	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	59%	100%
P0C950	Aspergillus niger	58%	100%
P0C951	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	59%	100%
P0CM16	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	31%	100%
P0CM17	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	31%	100%
P0CR30	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	58%	100%
P0CR31	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	58%	100%
P0CT16	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	60%	100%
P0CT17	Magnaporthe oryzae (strain Y34)	60%	100%
P0DH91	Arabidopsis thaliana	30%	100%
P11076	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	31%	100%
P19146	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	30%	100%
P20606	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	55%	100%
P22274	Candida albicans (strain SC5314 / ATCC MYA-2876)	31%	100%
P25160	Drosophila melanogaster	32%	100%
P26990	Gallus gallus	34%	100%
P26991	Giardia intestinalis	32%	100%
P34212	Caenorhabditis elegans	31%	100%
P34727	Ajellomyces capsulatus	32%	100%
P36397	Arabidopsis thaliana	30%	100%
P36405	Homo sapiens	33%	100%
P36536	Mus musculus	51%	98%
P36579	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	31%	100%
P37996	Rattus norvegicus	32%	100%
P38116	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	33%	100%
P40616	Homo sapiens	32%	100%
P40617	Homo sapiens	39%	98%
P40940	Arabidopsis thaliana	33%	100%
P40945	Drosophila melanogaster	31%	100%
P49076	Zea mays	30%	100%
P49702	Gallus gallus	32%	100%
P49703	Homo sapiens	32%	97%
P51643	Xenopus laevis	30%	100%
P51644	Xenopus laevis	34%	100%
P51645	Xenopus laevis	33%	100%
P51646	Rattus norvegicus	28%	100%
P51821	Chlamydomonas reinhardtii	31%	100%
P51822	Daucus carota	30%	100%
P51823	Oryza sativa subsp. japonica	30%	100%
P51824	Solanum tuberosum	30%	99%
P52884	Solanum lycopersicum	56%	100%
P52885	Nicotiana tabacum	49%	98%
P61204	Homo sapiens	30%	100%
P61205	Mus musculus	30%	100%
P61206	Rattus norvegicus	30%	100%
P61207	Takifugu rubripes	30%	100%
P61209	Drosophila melanogaster	31%	100%
P61210	Locusta migratoria	31%	100%
P61211	Mus musculus	32%	100%
P61212	Rattus norvegicus	32%	100%
P61213	Mus musculus	39%	98%
P61214	Rattus norvegicus	39%	98%
P62330	Homo sapiens	34%	100%
P62331	Mus musculus	34%	100%
P62332	Rattus norvegicus	34%	100%
P78976	Hypocrea jecorina	59%	100%
P84077	Homo sapiens	30%	100%
P84078	Mus musculus	30%	100%
P84079	Rattus norvegicus	30%	100%
P84080	Bos taurus	30%	100%
P84081	Bos taurus	31%	100%
P84082	Rattus norvegicus	31%	100%
P84083	Rattus norvegicus	32%	100%
P84084	Mus musculus	32%	100%
P84085	Homo sapiens	32%	100%
P91924	Dugesia japonica	31%	100%
Q007T5	Sus scrofa	34%	100%
Q01474	Arabidopsis thaliana	56%	100%
Q01475	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	55%	100%
Q06396	Oryza sativa subsp. japonica	30%	100%
Q09767	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	30%	100%
Q0CUN7	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	59%	100%
Q0IIM2	Bos taurus	26%	100%
Q0UKC0	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	60%	100%
Q0VC18	Bos taurus	32%	98%
Q10943	Caenorhabditis elegans	31%	100%
Q13795	Homo sapiens	27%	97%
Q18510	Caenorhabditis elegans	31%	100%
Q1MTE5	Danio rerio	32%	100%
Q1ZXA5	Dictyostelium discoideum	27%	100%
Q20758	Caenorhabditis elegans	30%	100%
Q23445	Caenorhabditis elegans	54%	100%
Q25761	Plasmodium falciparum (isolate NF54)	29%	100%
Q2HA55	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	57%	100%
Q2KI07	Bos taurus	29%	100%
Q2KJ96	Bos taurus	28%	100%
Q2TBW6	Bos taurus	33%	100%
Q2YDM1	Bos taurus	31%	100%
Q32LJ2	Bos taurus	27%	97%
Q3SXC5	Mus musculus	32%	100%
Q3T0D7	Bos taurus	51%	98%
Q3T0M9	Bos taurus	39%	98%
Q3T0T7	Bos taurus	52%	98%
Q4P0I7	Ustilago maydis (strain 521 / FGSC 9021)	56%	100%
Q4Q0D7	Leishmania major	33%	95%
Q4Q5Y0	Leishmania major	32%	96%
Q4Q756	Leishmania major	29%	100%
Q4QEJ1	Leishmania major	31%	98%
Q4QEM9	Leishmania major	26%	99%
Q4QJK0	Leishmania major	98%	100%
Q4R4S4	Macaca fascicularis	30%	100%
Q4R5P2	Macaca fascicularis	30%	100%
Q4WJS7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	59%	100%
Q52NJ3	Sus scrofa	51%	98%
Q52NJ4	Sus scrofa	33%	100%
Q54HK2	Dictyostelium discoideum	33%	100%
Q54JJ3	Dictyostelium discoideum	32%	100%
Q54R04	Dictyostelium discoideum	31%	100%
Q54UF1	Dictyostelium discoideum	31%	100%
Q54V41	Dictyostelium discoideum	32%	100%
Q54V47	Dictyostelium discoideum	32%	100%
Q54Y14	Dictyostelium discoideum	34%	100%
Q559R0	Dictyostelium discoideum	54%	100%
Q55AD9	Dictyostelium discoideum	27%	100%
Q58DI9	Bos taurus	33%	100%
Q59S78	Candida albicans (strain SC5314 / ATCC MYA-2876)	56%	100%
Q5BGB9	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	58%	100%
Q5E9I6	Bos taurus	30%	100%
Q5H913	Homo sapiens	29%	67%
Q5HZY2	Rattus norvegicus	52%	98%
Q5M9P8	Danio rerio	26%	100%
Q5PYH3	Sus scrofa	52%	98%
Q5R4G5	Pongo abelii	26%	100%
Q5R548	Pongo abelii	51%	98%
Q5R579	Pongo abelii	27%	97%
Q5R5P7	Pongo abelii	30%	100%
Q5R6E7	Pongo abelii	29%	100%
Q5REU3	Pongo abelii	32%	97%
Q5VLR7	Leishmania donovani	32%	100%
Q5ZKQ8	Gallus gallus	30%	100%
Q60Z38	Caenorhabditis briggsae	31%	100%
Q61LA8	Caenorhabditis briggsae	31%	100%
Q63055	Rattus norvegicus	29%	97%
Q66HA6	Rattus norvegicus	29%	100%
Q6BVA7	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	57%	100%
Q6CB54	Yarrowia lipolytica (strain CLIB 122 / E 150)	59%	100%
Q6CWR7	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	55%	100%
Q6FUZ9	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	54%	100%
Q6IMM3	Leishmania major	32%	100%
Q6NZW8	Danio rerio	30%	100%
Q6P8C8	Xenopus tropicalis	30%	100%
Q6T311	Homo sapiens	35%	100%
Q755D7	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	56%	100%
Q75A26	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	30%	100%
Q7KQL3	Plasmodium falciparum (isolate 3D7)	29%	100%
Q7RVM2	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	32%	100%
Q80ZU0	Mus musculus	28%	100%
Q877B9	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	60%	100%
Q8BSL7	Mus musculus	31%	100%
Q8BXL7	Mus musculus	29%	97%
Q8MQT8	Giardia intestinalis	46%	100%
Q8N4G2	Homo sapiens	33%	100%
Q8N8L6	Homo sapiens	33%	80%
Q8QHI3	Xenopus laevis	33%	100%
Q8SQH8	Encephalitozoon cuniculi (strain GB-M1)	34%	94%
Q8VEH3	Mus musculus	30%	100%
Q8VY57	Arabidopsis thaliana	35%	100%
Q8W4C8	Arabidopsis thaliana	32%	100%
Q93Y31	Arabidopsis thaliana	35%	100%
Q94231	Caenorhabditis elegans	35%	100%
Q94650	Plasmodium falciparum	29%	100%
Q96361	Brassica rapa subsp. pekinensis	34%	100%
Q96BM9	Homo sapiens	30%	100%
Q96KC2	Homo sapiens	27%	100%
Q99PE9	Mus musculus	31%	97%
Q9CQC9	Mus musculus	52%	98%
Q9CQW2	Mus musculus	29%	100%
Q9D4P0	Mus musculus	27%	100%
Q9H0F7	Homo sapiens	26%	100%
Q9LQC8	Arabidopsis thaliana	30%	100%
Q9N6B0	Leishmania donovani	32%	100%
Q9NR31	Homo sapiens	51%	98%
Q9NVJ2	Homo sapiens	29%	100%
Q9P4C8	Komagataella phaffii (strain GS115 / ATCC 20864)	53%	100%
Q9QVY3	Cricetulus griseus	52%	98%
Q9QXJ4	Mus musculus	33%	80%
Q9VHV5	Drosophila melanogaster	32%	100%
Q9WUL7	Mus musculus	33%	100%
Q9XZX2	Leishmania major	40%	100%
Q9Y689	Homo sapiens	28%	100%
Q9Y6B6	Homo sapiens	52%	98%
Q9Y7Z2	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	38%	100%
Q9ZPX1	Arabidopsis thaliana	32%	100%
V5B891	Trypanosoma cruzi	31%	100%
V5DJR8	Trypanosoma cruzi	31%	100%