Leucine-rich repeat protein (LRRP)

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AKA1_LEIMU

TriTrypDb:

LmxM.04.1200

Length:

187

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 13
NetGPI	no	yes: 0, no: 13

Show entries

Cellular components
Term	Name	Level	Count
GO:0005929	cilium	4	14
GO:0016020	membrane	2	1
GO:0042995	cell projection	2	14
GO:0043226	organelle	2	14
GO:0043227	membrane-bounded organelle	3	14
GO:0110165	cellular anatomical entity	1	14
GO:0120025	plasma membrane bounded cell projection	3	14

Previous1Next

Expansion

Sequence features

E9AKA1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AKA1

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0006793	phosphorus metabolic process	3	2
GO:0006796	phosphate-containing compound metabolic process	4	2
GO:0008152	metabolic process	1	2
GO:0009987	cellular process	1	2
GO:0016310	phosphorylation	5	2
GO:0044237	cellular metabolic process	2	2

Previous1Next

Show entries

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	2
GO:0016301	kinase activity	4	2
GO:0016740	transferase activity	2	2
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	2

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	123	127	PF00656	0.366
CLV_NRD_NRD_1	15	17	PF00675	0.723
CLV_PCSK_KEX2_1	172	174	PF00082	0.571
CLV_PCSK_KEX2_1	4	6	PF00082	0.728
CLV_PCSK_PC1ET2_1	172	174	PF00082	0.571
CLV_PCSK_PC1ET2_1	4	6	PF00082	0.755
DEG_APCC_DBOX_1	161	169	PF00400	0.415
DOC_CYCLIN_RxL_1	22	32	PF00134	0.566
DOC_MAPK_gen_1	22	30	PF00069	0.582
DOC_USP7_MATH_1	48	52	PF00917	0.463

Previous1 2 3 4 5 6 7Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I143	Leptomonas seymouri	68%	92%
A0A0S4IYV0	Bodo saltans	43%	97%
A0A0S4JTE7	Bodo saltans	43%	97%
A0A1X0NKZ2	Trypanosomatidae	44%	100%
A0A3S5H5F3	Leishmania donovani	94%	100%
A0A422NNV2	Trypanosoma rangeli	46%	100%
A4H435	Leishmania braziliensis	81%	100%
A4HSB9	Leishmania infantum	94%	100%
C9ZYB3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
O97000	Leishmania major	94%	100%

Previous1 2Next