Nucleolin_bd domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AK81_LEIMU

TriTrypDb:

LmxM.04.0990

Length:

292

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AK81

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AK81

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	100	104	PF00656	0.795
CLV_C14_Caspase3-7	150	154	PF00656	0.710
CLV_NRD_NRD_1	183	185	PF00675	0.491
CLV_NRD_NRD_1	249	251	PF00675	0.654
CLV_PCSK_FUR_1	230	234	PF00082	0.545
CLV_PCSK_KEX2_1	227	229	PF00082	0.464
CLV_PCSK_KEX2_1	232	234	PF00082	0.480
CLV_PCSK_KEX2_1	249	251	PF00082	0.654
CLV_PCSK_PC1ET2_1	227	229	PF00082	0.506
CLV_PCSK_PC1ET2_1	232	234	PF00082	0.420
CLV_PCSK_PC7_1	228	234	PF00082	0.447
CLV_PCSK_SKI1_1	205	209	PF00082	0.372
CLV_PCSK_SKI1_1	70	74	PF00082	0.634
CLV_Separin_Metazoa	13	17	PF03568	0.593
DEG_SPOP_SBC_1	114	118	PF00917	0.492
DOC_CYCLIN_RxL_1	202	212	PF00134	0.289
DOC_MAPK_gen_1	227	237	PF00069	0.608
DOC_MAPK_gen_1	252	262	PF00069	0.652
DOC_MAPK_HePTP_8	7	19	PF00069	0.589
DOC_MAPK_MEF2A_6	10	19	PF00069	0.536
DOC_USP7_MATH_1	114	118	PF00917	0.688
DOC_USP7_MATH_1	164	168	PF00917	0.688
DOC_USP7_MATH_1	195	199	PF00917	0.588
DOC_USP7_MATH_1	275	279	PF00917	0.643
DOC_USP7_UBL2_3	223	227	PF12436	0.601
DOC_WW_Pin1_4	273	278	PF00397	0.667
LIG_14-3-3_CanoR_1	184	189	PF00244	0.517
LIG_14-3-3_CanoR_1	283	288	PF00244	0.753
LIG_14-3-3_CanoR_1	53	57	PF00244	0.435
LIG_BIR_II_1	1	5	PF00653	0.603
LIG_BIR_III_2	43	47	PF00653	0.344
LIG_eIF4E_1	202	208	PF01652	0.417
LIG_FHA_1	10	16	PF00498	0.453
LIG_FHA_2	192	198	PF00498	0.641
LIG_FHA_2	92	98	PF00498	0.582
LIG_NRBOX	10	16	PF00104	0.587
LIG_SH2_SRC	49	52	PF00017	0.398
LIG_SH2_STAT5	202	205	PF00017	0.454
LIG_SH2_STAT5	49	52	PF00017	0.460
LIG_SH3_3	187	193	PF00018	0.633
LIG_SUMO_SIM_anti_2	234	239	PF11976	0.529
LIG_TRAF2_1	109	112	PF00917	0.502
LIG_TRAF2_1	194	197	PF00917	0.647
MOD_CK1_1	168	174	PF00069	0.569
MOD_CK1_1	278	284	PF00069	0.590
MOD_CK1_1	52	58	PF00069	0.577
MOD_CK1_1	92	98	PF00069	0.788
MOD_CK2_1	168	174	PF00069	0.694
MOD_CK2_1	191	197	PF00069	0.648
MOD_CK2_1	91	97	PF00069	0.584
MOD_GlcNHglycan	145	148	PF01048	0.671
MOD_GlcNHglycan	162	165	PF01048	0.703
MOD_GlcNHglycan	167	170	PF01048	0.736
MOD_GlcNHglycan	277	280	PF01048	0.664
MOD_GSK3_1	160	167	PF00069	0.667
MOD_GSK3_1	191	198	PF00069	0.641
MOD_GSK3_1	278	285	PF00069	0.759
MOD_GSK3_1	92	99	PF00069	0.499
MOD_LATS_1	189	195	PF00433	0.560
MOD_N-GLC_1	24	29	PF02516	0.629
MOD_N-GLC_1	268	273	PF02516	0.548
MOD_N-GLC_1	92	97	PF02516	0.708
MOD_PIKK_1	268	274	PF00454	0.702
MOD_PKA_1	143	149	PF00069	0.785
MOD_PKA_1	184	190	PF00069	0.514
MOD_PKA_2	282	288	PF00069	0.629
MOD_PKA_2	52	58	PF00069	0.440
MOD_Plk_1	195	201	PF00069	0.633
MOD_Plk_1	24	30	PF00069	0.623
MOD_Plk_2-3	96	102	PF00069	0.718
MOD_Plk_4	283	289	PF00069	0.730
MOD_Plk_4	52	58	PF00069	0.516
MOD_ProDKin_1	273	279	PF00069	0.667
MOD_SUMO_for_1	231	234	PF00179	0.456
MOD_SUMO_rev_2	2	12	PF00179	0.471
TRG_ER_diArg_1	249	252	PF00400	0.656
TRG_NLS_MonoExtN_4	142	147	PF00514	0.733

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A1X0NKX9	Trypanosomatidae	36%	100%
A0A3R7MS09	Trypanosoma rangeli	35%	68%
A0A3S5H5E1	Leishmania donovani	80%	100%
A4H414	Leishmania braziliensis	65%	100%
A4HS97	Leishmania infantum	81%	100%
V5DEF7	Trypanosoma cruzi	36%	100%