LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AK80_LEIMU
TriTrypDb:
LmxM.04.0980
Length:
1222

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AK80
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AK80

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 436 440 PF00656 0.696
CLV_C14_Caspase3-7 605 609 PF00656 0.558
CLV_C14_Caspase3-7 61 65 PF00656 0.659
CLV_C14_Caspase3-7 88 92 PF00656 0.718
CLV_NRD_NRD_1 1017 1019 PF00675 0.699
CLV_NRD_NRD_1 1118 1120 PF00675 0.646
CLV_NRD_NRD_1 265 267 PF00675 0.600
CLV_NRD_NRD_1 275 277 PF00675 0.675
CLV_NRD_NRD_1 317 319 PF00675 0.755
CLV_NRD_NRD_1 405 407 PF00675 0.668
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I1N9 Leptomonas seymouri 45% 98%
A0A3R7NJ02 Trypanosoma rangeli 33% 100%
A0A3S5H5E0 Leishmania donovani 90% 98%
A4H413 Leishmania braziliensis 73% 100%
A4HS96 Leishmania infantum 90% 98%
Q9NF97 Leishmania major 87% 98%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS