Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E9AK79_LEIMU

TriTrypDb:

LmxM.04.0975

Length:

466

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AK79

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AK79

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	34	36	PF00675	0.563
CLV_NRD_NRD_1	62	64	PF00675	0.723
CLV_NRD_NRD_1	72	74	PF00675	0.614
CLV_PCSK_FUR_1	32	36	PF00082	0.565
CLV_PCSK_KEX2_1	34	36	PF00082	0.563
CLV_PCSK_KEX2_1	62	64	PF00082	0.715
CLV_PCSK_PC7_1	30	36	PF00082	0.564
DEG_SPOP_SBC_1	137	141	PF00917	0.725
DOC_CKS1_1	165	170	PF01111	0.510
DOC_CYCLIN_yCln2_LP_2	119	122	PF00134	0.747
DOC_CYCLIN_yCln2_LP_2	232	238	PF00134	0.595
DOC_MAPK_DCC_7	115	125	PF00069	0.743
DOC_MAPK_FxFP_2	293	296	PF00069	0.527
DOC_MAPK_MEF2A_6	117	125	PF00069	0.588
DOC_PP2B_LxvP_1	119	122	PF13499	0.747
DOC_PP2B_LxvP_1	232	235	PF13499	0.598
DOC_PP2B_LxvP_1	46	49	PF13499	0.682
DOC_PP2B_LxvP_1	68	71	PF13499	0.511
DOC_PP4_FxxP_1	293	296	PF00568	0.527
DOC_PP4_MxPP_1	436	439	PF00568	0.565
DOC_USP7_MATH_1	100	104	PF00917	0.680
DOC_USP7_MATH_1	124	128	PF00917	0.562
DOC_USP7_MATH_1	211	215	PF00917	0.705
DOC_USP7_MATH_1	355	359	PF00917	0.695
DOC_USP7_MATH_1	428	432	PF00917	0.558
DOC_USP7_MATH_2	203	209	PF00917	0.544
DOC_WW_Pin1_4	164	169	PF00397	0.509
DOC_WW_Pin1_4	191	196	PF00397	0.752
DOC_WW_Pin1_4	215	220	PF00397	0.686
DOC_WW_Pin1_4	230	235	PF00397	0.638
DOC_WW_Pin1_4	236	241	PF00397	0.579
DOC_WW_Pin1_4	315	320	PF00397	0.783
DOC_WW_Pin1_4	359	364	PF00397	0.765
DOC_WW_Pin1_4	36	41	PF00397	0.645
DOC_WW_Pin1_4	373	378	PF00397	0.566
DOC_WW_Pin1_4	451	456	PF00397	0.741
LIG_14-3-3_CanoR_1	285	291	PF00244	0.700
LIG_14-3-3_CanoR_1	349	353	PF00244	0.629
LIG_APCC_ABBAyCdc20_2	10	16	PF00400	0.592
LIG_EVH1_1	104	108	PF00568	0.524
LIG_EVH1_2	121	125	PF00568	0.668
LIG_FHA_1	175	181	PF00498	0.738
LIG_FHA_2	138	144	PF00498	0.747
LIG_FHA_2	165	171	PF00498	0.693
LIG_FHA_2	274	280	PF00498	0.530
LIG_FHA_2	340	346	PF00498	0.738
LIG_FHA_2	385	391	PF00498	0.678
LIG_LIR_Apic_2	433	438	PF02991	0.721
LIG_LIR_Nem_3	131	136	PF02991	0.745
LIG_MAD2	405	413	PF02301	0.477
LIG_MYND_1	199	203	PF01753	0.529
LIG_Pex14_1	7	11	PF04695	0.544
LIG_Pex14_1	92	96	PF04695	0.643
LIG_SH2_CRK	96	100	PF00017	0.585
LIG_SH2_STAT5	136	139	PF00017	0.742
LIG_SH2_STAT5	8	11	PF00017	0.624
LIG_SH3_1	54	60	PF00018	0.653
LIG_SH3_2	57	62	PF14604	0.749
LIG_SH3_3	102	108	PF00018	0.620
LIG_SH3_3	115	121	PF00018	0.684
LIG_SH3_3	146	152	PF00018	0.735
LIG_SH3_3	162	168	PF00018	0.530
LIG_SH3_3	193	199	PF00018	0.753
LIG_SH3_3	218	224	PF00018	0.625
LIG_SH3_3	231	237	PF00018	0.635
LIG_SH3_3	240	246	PF00018	0.682
LIG_SH3_3	261	267	PF00018	0.544
LIG_SH3_3	308	314	PF00018	0.837
LIG_SH3_3	335	341	PF00018	0.560
LIG_SH3_3	360	366	PF00018	0.820
LIG_SH3_3	37	43	PF00018	0.561
LIG_SH3_3	403	409	PF00018	0.689
LIG_SH3_3	52	58	PF00018	0.663
LIG_SH3_CIN85_PxpxPR_1	49	54	PF14604	0.603
LIG_TRAF2_1	319	322	PF00917	0.557
LIG_WW_2	314	317	PF00397	0.636
MOD_CK1_1	138	144	PF00069	0.780
MOD_CK1_1	358	364	PF00069	0.778
MOD_CK2_1	273	279	PF00069	0.659
MOD_CK2_1	339	345	PF00069	0.715
MOD_CK2_1	384	390	PF00069	0.706
MOD_GlcNHglycan	126	129	PF01048	0.669
MOD_GlcNHglycan	207	210	PF01048	0.715
MOD_GlcNHglycan	260	263	PF01048	0.485
MOD_GlcNHglycan	357	360	PF01048	0.814
MOD_GlcNHglycan	419	423	PF01048	0.681
MOD_GlcNHglycan	432	435	PF01048	0.564
MOD_GSK3_1	211	218	PF00069	0.539
MOD_GSK3_1	355	362	PF00069	0.654
MOD_GSK3_1	364	371	PF00069	0.730
MOD_GSK3_1	426	433	PF00069	0.687
MOD_N-GLC_1	397	402	PF02516	0.604
MOD_NEK2_1	1	6	PF00069	0.677
MOD_NEK2_1	111	116	PF00069	0.678
MOD_NEK2_1	174	179	PF00069	0.509
MOD_PKA_2	348	354	PF00069	0.627
MOD_Plk_1	111	117	PF00069	0.587
MOD_Plk_2-3	384	390	PF00069	0.679
MOD_Plk_4	185	191	PF00069	0.593
MOD_Plk_4	23	29	PF00069	0.621
MOD_ProDKin_1	164	170	PF00069	0.510
MOD_ProDKin_1	191	197	PF00069	0.753
MOD_ProDKin_1	215	221	PF00069	0.681
MOD_ProDKin_1	230	236	PF00069	0.635
MOD_ProDKin_1	315	321	PF00069	0.782
MOD_ProDKin_1	359	365	PF00069	0.762
MOD_ProDKin_1	36	42	PF00069	0.653
MOD_ProDKin_1	373	379	PF00069	0.565
MOD_ProDKin_1	451	457	PF00069	0.740
TRG_DiLeu_BaLyEn_6	221	226	PF01217	0.525
TRG_DiLeu_BaLyEn_6	391	396	PF01217	0.446
TRG_ENDOCYTIC_2	96	99	PF00928	0.584
TRG_ER_diArg_1	115	118	PF00400	0.517
TRG_ER_diArg_1	29	32	PF00400	0.627
TRG_ER_diArg_1	61	63	PF00400	0.715
TRG_ER_diArg_1	77	80	PF00400	0.570

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H5D9	Leishmania donovani	70%	97%
A4H412	Leishmania braziliensis	53%	90%
A4HS95	Leishmania infantum	70%	97%
E9ACP9	Leishmania major	71%	99%