Putative ADP-ribosylation factor

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ADP-ribosylation factor, putative

Species:

Leishmania mexicana

UniProt:

E9AK30_LEIMU

TriTrypDb:

LmxM.04.0480

Length:

169

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	2
GO:0005794	Golgi apparatus	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

Expansion

Sequence features

E9AK30

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AK30

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	2
GO:0006886	intracellular protein transport	4	1
GO:0008104	protein localization	4	2
GO:0009987	cellular process	1	2
GO:0015031	protein transport	4	2
GO:0016192	vesicle-mediated transport	4	2
GO:0033036	macromolecule localization	2	2
GO:0045184	establishment of protein localization	3	2
GO:0046907	intracellular transport	3	1
GO:0051179	localization	1	2
GO:0051234	establishment of localization	2	2
GO:0051641	cellular localization	2	2
GO:0051649	establishment of localization in cell	3	1
GO:0070727	cellular macromolecule localization	3	2
GO:0071702	organic substance transport	4	2
GO:0071705	nitrogen compound transport	4	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003824	catalytic activity	1	12
GO:0003924	GTPase activity	7	12
GO:0005488	binding	1	12
GO:0005525	GTP binding	5	12
GO:0016462	pyrophosphatase activity	5	12
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	12
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	12
GO:0017076	purine nucleotide binding	4	12
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	12
GO:0019001	guanyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032561	guanyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	126	130	PF00656	0.428
CLV_PCSK_KEX2_1	51	53	PF00082	0.402
CLV_PCSK_PC1ET2_1	51	53	PF00082	0.402
CLV_PCSK_SKI1_1	38	42	PF00082	0.326
CLV_PCSK_SKI1_1	87	91	PF00082	0.385
DEG_APCC_DBOX_1	82	90	PF00400	0.318
DOC_CYCLIN_yCln2_LP_2	90	96	PF00134	0.270
DOC_MAPK_DCC_7	22	30	PF00069	0.352
DOC_MAPK_MEF2A_6	22	30	PF00069	0.382
DOC_PP1_RVXF_1	36	43	PF00149	0.317
DOC_USP7_MATH_1	77	81	PF00917	0.155
DOC_WW_Pin1_4	111	116	PF00397	0.274
LIG_14-3-3_CanoR_1	38	43	PF00244	0.402
LIG_14-3-3_CanoR_1	52	57	PF00244	0.402
LIG_14-3-3_CanoR_1	76	86	PF00244	0.430
LIG_14-3-3_CanoR_1	87	93	PF00244	0.407
LIG_BIR_III_4	5	9	PF00653	0.317
LIG_FHA_1	39	45	PF00498	0.356
LIG_FHA_1	8	14	PF00498	0.308
LIG_FHA_2	112	118	PF00498	0.293
LIG_FHA_2	9	15	PF00498	0.402
LIG_LIR_Nem_3	152	158	PF02991	0.274
LIG_LIR_Nem_3	34	40	PF02991	0.317
LIG_LIR_Nem_3	55	60	PF02991	0.289
LIG_NRBOX	85	91	PF00104	0.274
LIG_PCNA_PIPBox_1	50	59	PF02747	0.317
LIG_PCNA_yPIPBox_3	50	58	PF02747	0.274
LIG_PDZ_Class_3	164	169	PF00595	0.464
LIG_Pex14_1	57	61	PF04695	0.317
LIG_PTB_Apo_2	36	43	PF02174	0.336
LIG_SH2_CRK	37	41	PF00017	0.317
LIG_SH2_STAT5	135	138	PF00017	0.381
LIG_SH2_STAT5	142	145	PF00017	0.340
LIG_TYR_ITIM	35	40	PF00017	0.317
LIG_UBA3_1	100	106	PF00899	0.304
LIG_UBA3_1	12	17	PF00899	0.384
MOD_CK2_1	111	117	PF00069	0.293
MOD_N-GLC_1	38	43	PF02516	0.409
MOD_PKA_2	21	27	PF00069	0.402
MOD_PKA_2	77	83	PF00069	0.344
MOD_Plk_1	38	44	PF00069	0.330
MOD_Plk_4	8	14	PF00069	0.343
MOD_ProDKin_1	111	117	PF00069	0.274
TRG_DiLeu_BaEn_1	85	90	PF01217	0.274
TRG_DiLeu_BaLyEn_6	90	95	PF01217	0.318
TRG_ENDOCYTIC_2	155	158	PF00928	0.429
TRG_ENDOCYTIC_2	37	40	PF00928	0.317
TRG_ER_diArg_1	76	79	PF00400	0.365
TRG_Pf-PMV_PEXEL_1	125	129	PF00026	0.330
TRG_Pf-PMV_PEXEL_1	87	92	PF00026	0.319

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3Q3	Leptomonas seymouri	83%	89%
A0A0N0P4P7	Leptomonas seymouri	35%	93%
A0A0N0P633	Leptomonas seymouri	53%	92%
A0A0N0P8D4	Leptomonas seymouri	38%	94%
A0A0N0P8Z3	Leptomonas seymouri	37%	95%
A0A0N1HS40	Leptomonas seymouri	41%	97%
A0A0N1HTN6	Leptomonas seymouri	44%	89%
A0A0N1I3A9	Leptomonas seymouri	38%	94%
A0A0N1I556	Leptomonas seymouri	53%	95%
A0A0N1I6N0	Leptomonas seymouri	42%	99%
A0A0N1PD39	Leptomonas seymouri	37%	94%
A0A0S4IQT8	Bodo saltans	37%	90%
A0A0S4IS60	Bodo saltans	46%	99%
A0A0S4J2X3	Bodo saltans	44%	93%
A0A0S4J3L7	Bodo saltans	35%	94%
A0A0S4J5U8	Bodo saltans	41%	89%
A0A0S4J8H6	Bodo saltans	65%	94%
A0A0S4JHS1	Bodo saltans	29%	74%
A0A0S4JK65	Bodo saltans	43%	99%
A0A0S4JQ13	Bodo saltans	35%	87%
A0A0S4KJ70	Bodo saltans	55%	79%
A0A0S4KKS9	Bodo saltans	54%	96%
A0A1X0NKM5	Trypanosomatidae	42%	91%
A0A1X0NKZ8	Trypanosomatidae	41%	87%
A0A1X0NLB1	Trypanosomatidae	74%	89%
A0A1X0NLP5	Trypanosomatidae	35%	92%
A0A1X0NT19	Trypanosomatidae	41%	89%
A0A1X0NZX3	Trypanosomatidae	38%	95%
A0A1X0P0A2	Trypanosomatidae	36%	94%
A0A1X0P0D4	Trypanosomatidae	36%	88%
A0A1X0P1V3	Trypanosomatidae	28%	73%
A0A1X0P1Y5	Trypanosomatidae	34%	92%
A0A1X0P2L5	Trypanosomatidae	29%	87%
A0A1X0P5P0	Trypanosomatidae	54%	93%
A0A1X0P676	Trypanosomatidae	41%	88%
A0A3Q8IDS2	Leishmania donovani	32%	93%
A0A3Q8IFX9	Leishmania donovani	38%	94%
A0A3R7KSW8	Trypanosoma rangeli	37%	94%
A0A3R7L2X6	Trypanosoma rangeli	50%	100%
A0A3R7MW79	Trypanosoma rangeli	73%	89%
A0A3R7NC73	Trypanosoma rangeli	41%	89%
A0A3R7NMH3	Trypanosoma rangeli	37%	89%
A0A3R7RGT1	Trypanosoma rangeli	38%	92%
A0A3S5H598	Leishmania donovani	39%	92%
A0A3S5H5A9	Leishmania donovani	96%	89%
A0A3S5IQP0	Trypanosoma rangeli	43%	91%
A0A3S5ISB1	Trypanosoma rangeli	28%	92%
A0A3S7WU76	Leishmania donovani	42%	90%
A0A3S7X4X3	Leishmania donovani	53%	95%
A0A3S7X8N3	Leishmania donovani	41%	91%
A0A3S7XC57	Leishmania donovani	36%	95%
A0A422MUR1	Trypanosoma rangeli	28%	76%
A0A422MYB1	Trypanosoma rangeli	52%	93%
A0A422MZM4	Trypanosoma rangeli	33%	88%
A0A422NNC6	Trypanosoma rangeli	40%	88%
A0A422NRN0	Trypanosoma rangeli	36%	95%
A0A422NW53	Trypanosoma rangeli	35%	91%
A1CRG9	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	31%	89%
A1D4D1	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	32%	89%
A3LTA2	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	31%	89%
A4FV54	Bos taurus	28%	82%
A4H3V3	Leishmania braziliensis	38%	100%
A4H3W8	Leishmania braziliensis	92%	100%
A4H449	Leishmania braziliensis	30%	100%
A4H8R6	Leishmania braziliensis	32%	100%
A4H8V3	Leishmania braziliensis	42%	100%
A4HH98	Leishmania braziliensis	37%	100%
A4HJL1	Leishmania braziliensis	55%	100%
A4HJR7	Leishmania braziliensis	53%	100%
A4HLP5	Leishmania braziliensis	30%	78%
A4HM52	Leishmania braziliensis	42%	100%
A4HQE3	Leishmania braziliensis	36%	100%
A4HS29	Leishmania infantum	39%	92%
A4HS43	Leishmania infantum	96%	89%
A4HX34	Leishmania infantum	32%	93%
A4HX72	Leishmania infantum	42%	90%
A4I4E4	Leishmania infantum	39%	94%
A4I5R5	Leishmania infantum	38%	94%
A4I784	Leishmania infantum	53%	95%
A4IAR4	Leishmania infantum	41%	91%
A4IE34	Leishmania infantum	36%	95%
A5DR82	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	30%	89%
A5E5G3	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	29%	89%
A6NH57	Homo sapiens	36%	94%
A8ISN6	Chlamydomonas reinhardtii	38%	95%
B5FYQ0	Taeniopygia guttata	36%	93%
C9ZL19	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	95%
C9ZPY6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	87%
C9ZR33	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	92%
C9ZTU8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	89%
C9ZVV9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	89%
C9ZY21	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	88%
C9ZY41	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	73%	89%
C9ZZD4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	54%	93%
C9ZZD6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	54%	93%
D0A2E8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	91%
E9ADU4	Leishmania major	39%	100%
E9AEJ0	Leishmania major	42%	100%
E9AHL7	Leishmania infantum	53%	93%
E9AIU0	Leishmania braziliensis	38%	100%
E9AK16	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	100%
E9ALY6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	94%
E9AQU9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	93%
E9ARC9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	90%
E9AU58	Leishmania mexicana (strain MHOM/GT/2001/U1103)	37%	95%
E9B110	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	94%
E9B229	Leishmania mexicana (strain MHOM/GT/2001/U1103)	53%	93%
E9B278	Leishmania mexicana (strain MHOM/GT/2001/U1103)	53%	100%
E9B5Q1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	91%
F1PTE3	Canis lupus familiaris	28%	83%
F4IZ82	Arabidopsis thaliana	37%	96%
O00909	Dictyostelium discoideum	53%	93%
O04266	Brassica campestris	34%	88%
O04267	Brassica campestris	33%	87%
O04834	Arabidopsis thaliana	37%	88%
O08697	Rattus norvegicus	42%	92%
O23778	Catharanthus roseus	51%	93%
O24466	Arabidopsis thaliana	27%	78%
O42819	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	30%	79%
O45379	Caenorhabditis elegans	37%	92%
O48649	Salix bakko	53%	93%
O48920	Vigna unguiculata	53%	93%
O49513	Arabidopsis thaliana	29%	78%
O88848	Mus musculus	37%	91%
P07560	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	30%	79%
P0C583	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	32%	89%
P0C950	Aspergillus niger	30%	89%
P0C951	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	32%	89%
P0CM16	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	55%	93%
P0CM17	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	55%	93%
P0CR30	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	33%	89%
P0CR31	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	33%	89%
P0CT16	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	33%	89%
P0CT17	Magnaporthe oryzae (strain Y34)	33%	89%
P0DH91	Arabidopsis thaliana	53%	93%
P10536	Rattus norvegicus	28%	84%
P11076	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	51%	93%
P11620	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	28%	83%
P18085	Homo sapiens	52%	94%
P19146	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	50%	93%
P20606	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	89%
P22125	Diplobatis ommata	28%	84%
P22128	Diplobatis ommata	27%	80%
P22274	Candida albicans (strain SC5314 / ATCC MYA-2876)	53%	94%
P25160	Drosophila melanogaster	42%	94%
P26990	Gallus gallus	53%	97%
P26991	Giardia intestinalis	51%	88%
P28188	Arabidopsis thaliana	30%	83%
P33723	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	27%	83%
P34212	Caenorhabditis elegans	45%	95%
P34727	Ajellomyces capsulatus	55%	92%
P35280	Rattus norvegicus	28%	82%
P35286	Rattus norvegicus	28%	83%
P36397	Arabidopsis thaliana	53%	93%
P36404	Homo sapiens	41%	92%
P36405	Homo sapiens	35%	93%
P36536	Mus musculus	30%	85%
P36579	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	54%	94%
P36862	Volvox carteri	34%	83%
P37996	Rattus norvegicus	37%	93%
P38116	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	43%	92%
P39110	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	88%
P40616	Homo sapiens	43%	93%
P40617	Homo sapiens	40%	84%
P40940	Arabidopsis thaliana	44%	93%
P40945	Drosophila melanogaster	53%	94%
P40946	Drosophila melanogaster	52%	97%
P40994	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	47%	92%
P49076	Zea mays	55%	93%
P49702	Gallus gallus	53%	94%
P49703	Homo sapiens	39%	84%
P51153	Homo sapiens	28%	83%
P51643	Xenopus laevis	54%	93%
P51644	Xenopus laevis	52%	94%
P51645	Xenopus laevis	52%	97%
P51646	Rattus norvegicus	45%	94%
P51821	Chlamydomonas reinhardtii	53%	93%
P51822	Daucus carota	53%	93%
P51823	Oryza sativa subsp. japonica	52%	93%
P51824	Solanum tuberosum	53%	86%
P52884	Solanum lycopersicum	36%	88%
P55258	Mus musculus	28%	82%
P56559	Homo sapiens	41%	88%
P61006	Homo sapiens	28%	82%
P61007	Canis lupus familiaris	28%	82%
P61028	Mus musculus	26%	82%
P61204	Homo sapiens	54%	93%
P61205	Mus musculus	54%	93%
P61206	Rattus norvegicus	54%	93%
P61207	Takifugu rubripes	54%	93%
P61208	Mus musculus	41%	88%
P61209	Drosophila melanogaster	53%	93%
P61210	Locusta migratoria	53%	93%
P61211	Mus musculus	44%	93%
P61212	Rattus norvegicus	44%	93%
P61213	Mus musculus	40%	84%
P61214	Rattus norvegicus	40%	84%
P61750	Mus musculus	51%	94%
P61751	Rattus norvegicus	51%	94%
P62330	Homo sapiens	52%	97%
P62331	Mus musculus	52%	97%
P62332	Rattus norvegicus	52%	97%
P62820	Homo sapiens	28%	82%
P62821	Mus musculus	28%	82%
P62822	Canis lupus familiaris	28%	82%
P70550	Rattus norvegicus	26%	82%
P78976	Hypocrea jecorina	32%	89%
P84077	Homo sapiens	54%	93%
P84078	Mus musculus	54%	93%
P84079	Rattus norvegicus	54%	93%
P84080	Bos taurus	54%	93%
P84081	Bos taurus	54%	93%
P84082	Rattus norvegicus	54%	93%
P84083	Rattus norvegicus	53%	94%
P84084	Mus musculus	53%	94%
P84085	Homo sapiens	53%	94%
P91924	Dugesia japonica	55%	92%
Q007T5	Sus scrofa	52%	97%
Q01474	Arabidopsis thaliana	33%	88%
Q01475	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	89%
Q01890	Phytophthora infestans	28%	84%
Q02804	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	85%
Q05737	Zea mays	30%	83%
Q05974	Lymnaea stagnalis	28%	82%
Q06396	Oryza sativa subsp. japonica	53%	93%
Q06849	Drosophila melanogaster	41%	92%
Q06AU7	Sus scrofa	28%	84%
Q09767	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	91%
Q0CUN7	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	32%	89%
Q0IIM2	Bos taurus	38%	91%
Q0P5N6	Homo sapiens	30%	86%
Q0UKC0	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	31%	91%
Q0VC18	Bos taurus	39%	84%
Q10943	Caenorhabditis elegans	54%	93%
Q13795	Homo sapiens	34%	84%
Q18510	Caenorhabditis elegans	35%	89%
Q19705	Caenorhabditis elegans	42%	92%
Q1MTE5	Danio rerio	36%	93%
Q1ZXA5	Dictyostelium discoideum	31%	91%
Q20758	Caenorhabditis elegans	44%	94%
Q23445	Caenorhabditis elegans	33%	88%
Q25761	Plasmodium falciparum (isolate NF54)	50%	93%
Q29RR0	Bos taurus	31%	66%
Q2HA55	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	33%	89%
Q2HJH2	Bos taurus	28%	84%
Q2HJI8	Bos taurus	26%	82%
Q2KI07	Bos taurus	34%	91%
Q2KJ96	Bos taurus	45%	94%
Q2TA37	Bos taurus	41%	92%
Q2TBW6	Bos taurus	36%	93%
Q2YDM1	Bos taurus	44%	93%
Q32LJ2	Bos taurus	34%	84%
Q39222	Arabidopsis thaliana	31%	78%
Q39434	Beta vulgaris	29%	79%
Q3SXC5	Mus musculus	39%	88%
Q3SZF2	Bos taurus	52%	94%
Q3T0D7	Bos taurus	30%	85%
Q3T0M9	Bos taurus	40%	84%
Q3T0T7	Bos taurus	32%	85%
Q40193	Lotus japonicus	29%	78%
Q40523	Nicotiana tabacum	30%	78%
Q4P0I7	Ustilago maydis (strain 521 / FGSC 9021)	31%	89%
Q4Q0D7	Leishmania major	36%	100%
Q4Q404	Leishmania major	31%	78%
Q4Q5Y0	Leishmania major	53%	100%
Q4Q756	Leishmania major	38%	100%
Q4QEJ1	Leishmania major	43%	100%
Q4QEM9	Leishmania major	32%	100%
Q4R4S4	Macaca fascicularis	39%	91%
Q4R5P1	Macaca fascicularis	28%	82%
Q4R5P2	Macaca fascicularis	54%	93%
Q4R8X3	Macaca fascicularis	28%	84%
Q4UB16	Theileria annulata	30%	77%
Q4WJS7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	32%	89%
Q52NJ2	Sus scrofa	28%	82%
Q52NJ3	Sus scrofa	30%	85%
Q52NJ4	Sus scrofa	36%	93%
Q53B90	Rattus norvegicus	32%	80%
Q54FL2	Dictyostelium discoideum	31%	86%
Q54HK2	Dictyostelium discoideum	45%	89%
Q54I24	Dictyostelium discoideum	41%	78%
Q54JJ3	Dictyostelium discoideum	48%	89%
Q54K69	Dictyostelium discoideum	33%	86%
Q54R04	Dictyostelium discoideum	38%	91%
Q54RX9	Dictyostelium discoideum	28%	79%
Q54UF1	Dictyostelium discoideum	42%	92%
Q54V41	Dictyostelium discoideum	50%	90%
Q54V47	Dictyostelium discoideum	50%	90%
Q54Y14	Dictyostelium discoideum	36%	87%
Q54YV7	Dictyostelium discoideum	22%	87%
Q559R0	Dictyostelium discoideum	32%	90%
Q55AD9	Dictyostelium discoideum	44%	92%
Q58DI9	Bos taurus	43%	93%
Q58DS5	Bos taurus	28%	83%
Q59S78	Candida albicans (strain SC5314 / ATCC MYA-2876)	29%	89%
Q5BGB9	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	32%	89%
Q5BK71	Rattus norvegicus	43%	98%
Q5E9I6	Bos taurus	54%	93%
Q5EA19	Bos taurus	29%	84%
Q5HZY2	Rattus norvegicus	33%	85%
Q5KTJ6	Mesocricetus auratus	27%	83%
Q5M9P8	Danio rerio	36%	91%
Q5PYH3	Sus scrofa	33%	85%
Q5R4A3	Pongo abelii	28%	82%
Q5R4G5	Pongo abelii	37%	91%
Q5R548	Pongo abelii	30%	85%
Q5R579	Pongo abelii	34%	84%
Q5R5P7	Pongo abelii	54%	93%
Q5R6E7	Pongo abelii	34%	91%
Q5RCF1	Pongo abelii	52%	94%
Q5RCQ6	Pongo abelii	27%	100%
Q5RE13	Pongo abelii	28%	84%
Q5REC9	Pongo abelii	26%	82%
Q5REU3	Pongo abelii	39%	84%
Q5RFN0	Pongo abelii	29%	83%
Q5VLR7	Leishmania donovani	53%	93%
Q5ZKQ8	Gallus gallus	34%	91%
Q60Z38	Caenorhabditis briggsae	36%	89%
Q61LA8	Caenorhabditis briggsae	54%	93%
Q627K4	Caenorhabditis briggsae	40%	92%
Q63055	Rattus norvegicus	36%	84%
Q66HA6	Rattus norvegicus	35%	91%
Q6BVA7	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	30%	89%
Q6CB54	Yarrowia lipolytica (strain CLIB 122 / E 150)	34%	89%
Q6CWR7	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	30%	89%
Q6FUZ9	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	32%	89%
Q6IMM3	Leishmania major	53%	100%
Q6NYB7	Rattus norvegicus	28%	82%
Q6NZW8	Danio rerio	36%	91%
Q6P068	Mus musculus	43%	94%
Q6P3A9	Mus musculus	43%	96%
Q6P8C8	Xenopus tropicalis	33%	91%
Q6T311	Homo sapiens	33%	90%
Q755D7	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	31%	89%
Q75A26	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	50%	93%
Q76NM7	Plasmodium falciparum (isolate 3D7)	30%	82%
Q7KQL3	Plasmodium falciparum (isolate 3D7)	51%	93%
Q7RVM2	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	55%	91%
Q7T3A4	Danio rerio	27%	84%
Q80ZU0	Mus musculus	45%	94%
Q86YS6	Homo sapiens	31%	80%
Q877B9	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	32%	89%
Q8BGR6	Mus musculus	29%	83%
Q8BSL7	Mus musculus	54%	93%
Q8BXL7	Mus musculus	36%	84%
Q8CG50	Mus musculus	32%	80%
Q8MQT8	Giardia intestinalis	31%	88%
Q8N4G2	Homo sapiens	39%	88%
Q8N8L6	Homo sapiens	35%	69%
Q8QHI3	Xenopus laevis	36%	93%
Q8SQH8	Encephalitozoon cuniculi (strain GB-M1)	39%	82%
Q8VEH3	Mus musculus	33%	91%
Q8VY57	Arabidopsis thaliana	33%	92%
Q8W4C8	Arabidopsis thaliana	39%	92%
Q92930	Homo sapiens	26%	82%
Q93Y31	Arabidopsis thaliana	33%	92%
Q94148	Caenorhabditis elegans	24%	84%
Q94231	Caenorhabditis elegans	48%	94%
Q94650	Plasmodium falciparum	51%	93%
Q96283	Arabidopsis thaliana	29%	78%
Q96361	Brassica rapa subsp. pekinensis	44%	93%
Q969Q4	Homo sapiens	43%	86%
Q96BM9	Homo sapiens	34%	91%
Q96KC2	Homo sapiens	42%	94%
Q99PE9	Mus musculus	40%	84%
Q9CQC9	Mus musculus	33%	85%
Q9CQW2	Mus musculus	35%	91%
Q9D0J4	Mus musculus	42%	92%
Q9D1G1	Mus musculus	28%	84%
Q9D4P0	Mus musculus	42%	94%
Q9DD03	Mus musculus	29%	84%
Q9FIF9	Arabidopsis thaliana	31%	78%
Q9H0F7	Homo sapiens	37%	91%
Q9H0U4	Homo sapiens	28%	84%
Q9JKM7	Mus musculus	29%	76%
Q9LNW1	Arabidopsis thaliana	29%	79%
Q9LQC8	Arabidopsis thaliana	53%	93%
Q9N6B0	Leishmania donovani	39%	94%
Q9NR31	Homo sapiens	30%	85%
Q9NVJ2	Homo sapiens	35%	91%
Q9NXU5	Homo sapiens	29%	83%
Q9P4C8	Komagataella phaffii (strain GS115 / ATCC 20864)	31%	89%
Q9QVY3	Cricetulus griseus	33%	85%
Q9QXJ4	Mus musculus	32%	70%
Q9SHU5	Arabidopsis thaliana	50%	82%
Q9TVU5	Theileria parva	29%	77%
Q9U0T6	Leishmania major	96%	100%
Q9ULW5	Homo sapiens	30%	66%
Q9VHV5	Drosophila melanogaster	35%	91%
Q9WUL7	Mus musculus	36%	93%
Q9XZX2	Leishmania major	40%	100%
Q9Y689	Homo sapiens	45%	94%
Q9Y6B6	Homo sapiens	33%	85%
Q9Y7Z2	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	52%	92%
Q9ZPX1	Arabidopsis thaliana	40%	91%
V5B891	Trypanosoma cruzi	41%	89%
V5DJR8	Trypanosoma cruzi	43%	91%