Surface antigen-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

surface antigen-like protein

Species:

Leishmania mexicana

UniProt:

E9AK02_LEIMU

TriTrypDb:

LmxM.04.0200

Length:

182

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 5, no: 0
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AK02

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AK02

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
DEG_Nend_UBRbox_3	1	3	PF02207	0.433
DEG_SPOP_SBC_1	25	29	PF00917	0.465
DEG_SPOP_SBC_1	66	70	PF00917	0.565
DEG_SPOP_SBC_1	90	94	PF00917	0.378
DOC_MAPK_MEF2A_6	162	170	PF00069	0.555
DOC_PP2B_LxvP_1	45	48	PF13499	0.483
DOC_USP7_MATH_1	145	149	PF00917	0.448
DOC_USP7_MATH_1	153	157	PF00917	0.452
DOC_USP7_MATH_1	25	29	PF00917	0.543
DOC_USP7_MATH_1	35	39	PF00917	0.547
DOC_USP7_MATH_1	40	44	PF00917	0.469
DOC_USP7_MATH_1	79	83	PF00917	0.527
DOC_USP7_MATH_1	89	93	PF00917	0.384
DOC_WW_Pin1_4	100	105	PF00397	0.432
DOC_WW_Pin1_4	53	58	PF00397	0.515
LIG_14-3-3_CanoR_1	162	167	PF00244	0.593
LIG_DLG_GKlike_1	162	170	PF00625	0.555
LIG_FHA_1	161	167	PF00498	0.500
LIG_FHA_1	2	8	PF00498	0.541
LIG_FHA_1	71	77	PF00498	0.601
LIG_FHA_2	58	64	PF00498	0.512
LIG_Integrin_isoDGR_2	133	135	PF01839	0.288
LIG_LIR_LC3C_4	163	168	PF02991	0.496
LIG_LIR_Nem_3	146	152	PF02991	0.543
LIG_PDZ_Class_1	177	182	PF00595	0.555
LIG_SUMO_SIM_par_1	171	177	PF11976	0.443
MOD_CDK_SPK_2	53	58	PF00069	0.494
MOD_CK1_1	156	162	PF00069	0.517
MOD_CK1_1	23	29	PF00069	0.586
MOD_CK1_1	49	55	PF00069	0.613
MOD_CK1_1	67	73	PF00069	0.534
MOD_CK1_1	81	87	PF00069	0.414
MOD_GlcNHglycan	22	25	PF01048	0.515
MOD_GlcNHglycan	31	34	PF01048	0.590
MOD_GSK3_1	156	163	PF00069	0.581
MOD_GSK3_1	20	27	PF00069	0.578
MOD_GSK3_1	46	53	PF00069	0.650
MOD_GSK3_1	62	69	PF00069	0.614
MOD_GSK3_1	75	82	PF00069	0.521
MOD_N-GLC_1	1	6	PF02516	0.422
MOD_N-GLC_2	97	99	PF02516	0.471
MOD_NEK2_1	1	6	PF00069	0.457
MOD_NEK2_1	161	166	PF00069	0.594
MOD_NEK2_1	174	179	PF00069	0.582
MOD_NEK2_2	145	150	PF00069	0.448
MOD_OFUCOSY	114	120	PF10250	0.441
MOD_PKA_2	161	167	PF00069	0.562
MOD_PKA_2	35	41	PF00069	0.551
MOD_PKA_2	57	63	PF00069	0.519
MOD_Plk_1	1	7	PF00069	0.419
MOD_Plk_4	15	21	PF00069	0.521
MOD_Plk_4	162	168	PF00069	0.685
MOD_ProDKin_1	100	106	PF00069	0.429
MOD_ProDKin_1	53	59	PF00069	0.517

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H585	Leishmania donovani	81%	100%
A0A3S7X2Y7	Leishmania donovani	37%	100%
A4HS15	Leishmania infantum	82%	100%
Q9XZY0	Leishmania major	80%	100%