Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AJZ2_LEIMU

TriTrypDb:

LmxM.04.0080

Length:

158

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AJZ2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AJZ2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	116	120	PF00656	0.358
CLV_C14_Caspase3-7	36	40	PF00656	0.638
CLV_NRD_NRD_1	16	18	PF00675	0.490
CLV_NRD_NRD_1	2	4	PF00675	0.650
CLV_NRD_NRD_1	71	73	PF00675	0.505
CLV_PCSK_KEX2_1	16	18	PF00082	0.490
CLV_PCSK_KEX2_1	2	4	PF00082	0.650
CLV_PCSK_KEX2_1	71	73	PF00082	0.505
CLV_PCSK_KEX2_1	91	93	PF00082	0.349
CLV_PCSK_PC1ET2_1	91	93	PF00082	0.363
CLV_PCSK_SKI1_1	101	105	PF00082	0.348
CLV_PCSK_SKI1_1	16	20	PF00082	0.475
CLV_PCSK_SKI1_1	3	7	PF00082	0.550
CLV_PCSK_SKI1_1	61	65	PF00082	0.496
DEG_APCC_DBOX_1	106	114	PF00400	0.508
DEG_APCC_DBOX_1	60	68	PF00400	0.504
DEG_APCC_DBOX_1	71	79	PF00400	0.391
DEG_Nend_UBRbox_1	1	4	PF02207	0.630
DEG_SCF_FBW7_2	75	80	PF00400	0.440
DEG_SPOP_SBC_1	138	142	PF00917	0.580
DOC_MAPK_MEF2A_6	61	69	PF00069	0.502
DOC_USP7_MATH_1	10	14	PF00917	0.557
DOC_USP7_MATH_1	137	141	PF00917	0.710
DOC_USP7_MATH_1	147	151	PF00917	0.576
DOC_WW_Pin1_4	3	8	PF00397	0.551
DOC_WW_Pin1_4	73	78	PF00397	0.432
LIG_14-3-3_CanoR_1	16	22	PF00244	0.713
LIG_FHA_1	48	54	PF00498	0.495
LIG_FHA_1	74	80	PF00498	0.386
LIG_FHA_2	114	120	PF00498	0.357
LIG_FHA_2	34	40	PF00498	0.635
LIG_FHA_2	54	60	PF00498	0.402
LIG_LIR_Nem_3	13	18	PF02991	0.586
LIG_LIR_Nem_3	57	63	PF02991	0.589
LIG_NRBOX	63	69	PF00104	0.500
LIG_PDZ_Class_2	153	158	PF00595	0.639
LIG_SH2_CRK	60	64	PF00017	0.580
LIG_SH3_3	126	132	PF00018	0.530
LIG_SH3_3	49	55	PF00018	0.612
MOD_CK1_1	45	51	PF00069	0.602
MOD_GlcNHglycan	149	152	PF01048	0.491
MOD_GlcNHglycan	44	47	PF01048	0.704
MOD_GSK3_1	41	48	PF00069	0.676
MOD_LATS_1	99	105	PF00433	0.504
MOD_N-GLC_1	40	45	PF02516	0.679
MOD_NEK2_1	113	118	PF00069	0.359
MOD_PKA_1	16	22	PF00069	0.625
MOD_PKA_1	71	77	PF00069	0.495
MOD_PKA_2	16	22	PF00069	0.688
MOD_PKA_2	71	77	PF00069	0.495
MOD_Plk_1	101	107	PF00069	0.616
MOD_Plk_1	120	126	PF00069	0.365
MOD_Plk_2-3	102	108	PF00069	0.427
MOD_Plk_4	113	119	PF00069	0.374
MOD_ProDKin_1	3	9	PF00069	0.550
MOD_ProDKin_1	73	79	PF00069	0.434
TRG_ENDOCYTIC_2	60	63	PF00928	0.580
TRG_ER_diArg_1	1	3	PF00400	0.672
TRG_ER_diArg_1	122	125	PF00400	0.532
TRG_ER_diArg_1	15	17	PF00400	0.494
TRG_ER_diArg_1	70	72	PF00400	0.500
TRG_NES_CRM1_1	73	88	PF08389	0.451
TRG_Pf-PMV_PEXEL_1	111	115	PF00026	0.534
TRG_Pf-PMV_PEXEL_1	61	66	PF00026	0.505

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H575	Leishmania donovani	88%	100%
A4H3S9	Leishmania braziliensis	68%	97%
A4HE83	Leishmania braziliensis	59%	97%
A4HS04	Leishmania infantum	89%	100%
Q9BLQ6	Leishmania major	89%	100%