DNA-directed DNA polymerase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AJW7_LEIMU

TriTrypDb:

LmxM.03.0830

Length:

341

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AJW7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AJW7

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	111	113	PF00675	0.633
CLV_NRD_NRD_1	25	27	PF00675	0.575
CLV_NRD_NRD_1	72	74	PF00675	0.443
CLV_NRD_NRD_1	87	89	PF00675	0.451
CLV_PCSK_KEX2_1	111	113	PF00082	0.611
CLV_PCSK_KEX2_1	239	241	PF00082	0.614
CLV_PCSK_KEX2_1	25	27	PF00082	0.575
CLV_PCSK_KEX2_1	87	89	PF00082	0.589
CLV_PCSK_PC1ET2_1	239	241	PF00082	0.646
CLV_PCSK_SKI1_1	111	115	PF00082	0.629

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P542	Leptomonas seymouri	66%	88%
A0A0S4IVU1	Bodo saltans	38%	100%
A0A1X0P922	Trypanosomatidae	49%	88%
A0A451EJT2	Leishmania donovani	95%	86%
A4H3P5	Leishmania braziliensis	84%	99%
C9ZKH7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	54%	100%
E8NHC8	Leishmania infantum	95%	86%
E9ACM8	Leishmania major	94%	100%
V5DTZ7	Trypanosoma cruzi	49%	85%

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