Palmitoyltransferase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E9AJW4_LEIMU

TriTrypDb:

LmxM.03.0810

Length:

1078

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	5
GO:0110165	cellular anatomical entity	1	5

Expansion

Sequence features

E9AJW4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AJW4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	185	189	PF00656	0.697
CLV_C14_Caspase3-7	213	217	PF00656	0.694
CLV_C14_Caspase3-7	585	589	PF00656	0.717
CLV_NRD_NRD_1	129	131	PF00675	0.555
CLV_NRD_NRD_1	139	141	PF00675	0.503
CLV_NRD_NRD_1	288	290	PF00675	0.529
CLV_NRD_NRD_1	357	359	PF00675	0.485
CLV_NRD_NRD_1	360	362	PF00675	0.474
CLV_NRD_NRD_1	414	416	PF00675	0.483
CLV_NRD_NRD_1	546	548	PF00675	0.459
CLV_NRD_NRD_1	692	694	PF00675	0.438
CLV_NRD_NRD_1	84	86	PF00675	0.549
CLV_NRD_NRD_1	859	861	PF00675	0.482
CLV_NRD_NRD_1	882	884	PF00675	0.519
CLV_PCSK_FUR_1	127	131	PF00082	0.499
CLV_PCSK_FUR_1	358	362	PF00082	0.490
CLV_PCSK_KEX2_1	129	131	PF00082	0.559
CLV_PCSK_KEX2_1	139	141	PF00082	0.499
CLV_PCSK_KEX2_1	357	359	PF00082	0.485
CLV_PCSK_KEX2_1	360	362	PF00082	0.474
CLV_PCSK_KEX2_1	413	415	PF00082	0.486
CLV_PCSK_KEX2_1	546	548	PF00082	0.471
CLV_PCSK_KEX2_1	692	694	PF00082	0.438
CLV_PCSK_KEX2_1	859	861	PF00082	0.482
CLV_PCSK_KEX2_1	86	88	PF00082	0.516
CLV_PCSK_KEX2_1	882	884	PF00082	0.519
CLV_PCSK_PC1ET2_1	86	88	PF00082	0.489
CLV_PCSK_PC7_1	353	359	PF00082	0.480
CLV_PCSK_PC7_1	82	88	PF00082	0.496
CLV_PCSK_SKI1_1	414	418	PF00082	0.463
CLV_PCSK_SKI1_1	57	61	PF00082	0.581
CLV_PCSK_SKI1_1	637	641	PF00082	0.542
CLV_PCSK_SKI1_1	692	696	PF00082	0.646
CLV_PCSK_SKI1_1	87	91	PF00082	0.517
DEG_APCC_DBOX_1	413	421	PF00400	0.670
DEG_APCC_DBOX_1	697	705	PF00400	0.729
DEG_Kelch_Keap1_1	214	219	PF01344	0.647
DEG_Nend_Nbox_1	1	3	PF02207	0.755
DEG_SPOP_SBC_1	237	241	PF00917	0.727
DEG_SPOP_SBC_1	615	619	PF00917	0.736
DOC_ANK_TNKS_1	826	833	PF00023	0.643
DOC_MAPK_DCC_7	827	835	PF00069	0.643
DOC_MAPK_MEF2A_6	1064	1072	PF00069	0.299
DOC_MAPK_MEF2A_6	421	430	PF00069	0.665
DOC_MAPK_MEF2A_6	827	835	PF00069	0.727
DOC_MAPK_MEF2A_6	950	958	PF00069	0.542
DOC_MAPK_RevD_3	869	883	PF00069	0.626
DOC_PP2B_LxvP_1	826	829	PF13499	0.747
DOC_PP4_FxxP_1	449	452	PF00568	0.490
DOC_PP4_FxxP_1	601	604	PF00568	0.659
DOC_USP7_MATH_1	1017	1021	PF00917	0.537
DOC_USP7_MATH_1	1029	1033	PF00917	0.492
DOC_USP7_MATH_1	174	178	PF00917	0.689
DOC_USP7_MATH_1	273	277	PF00917	0.800
DOC_USP7_MATH_1	28	32	PF00917	0.667
DOC_USP7_MATH_1	391	395	PF00917	0.707
DOC_USP7_MATH_1	399	403	PF00917	0.634
DOC_USP7_MATH_1	435	439	PF00917	0.399
DOC_USP7_MATH_1	478	482	PF00917	0.544
DOC_USP7_MATH_1	53	57	PF00917	0.773
DOC_USP7_MATH_1	615	619	PF00917	0.811
DOC_USP7_MATH_1	989	993	PF00917	0.535
DOC_USP7_MATH_2	650	656	PF00917	0.633
DOC_WW_Pin1_4	1010	1015	PF00397	0.504
DOC_WW_Pin1_4	256	261	PF00397	0.663
DOC_WW_Pin1_4	281	286	PF00397	0.701
DOC_WW_Pin1_4	480	485	PF00397	0.514
DOC_WW_Pin1_4	754	759	PF00397	0.760
DOC_WW_Pin1_4	924	929	PF00397	0.679
DOC_WW_Pin1_4	96	101	PF00397	0.768
LIG_14-3-3_CanoR_1	400	404	PF00244	0.600
LIG_14-3-3_CanoR_1	414	423	PF00244	0.664
LIG_14-3-3_CanoR_1	51	59	PF00244	0.662
LIG_14-3-3_CanoR_1	692	701	PF00244	0.816
LIG_14-3-3_CanoR_1	705	709	PF00244	0.715
LIG_14-3-3_CanoR_1	773	781	PF00244	0.736
LIG_14-3-3_CanoR_1	93	97	PF00244	0.723
LIG_14-3-3_CanoR_1	994	1003	PF00244	0.530
LIG_BIR_III_2	905	909	PF00653	0.714
LIG_BIR_III_4	787	791	PF00653	0.699
LIG_BRCT_BRCA1_1	275	279	PF00533	0.656
LIG_BRCT_BRCA1_1	637	641	PF00533	0.759
LIG_BRCT_BRCA1_1	94	98	PF00533	0.729
LIG_CtBP_PxDLS_1	152	156	PF00389	0.709
LIG_deltaCOP1_diTrp_1	539	549	PF00928	0.661
LIG_deltaCOP1_diTrp_1	974	984	PF00928	0.461
LIG_DLG_GKlike_1	700	708	PF00625	0.684
LIG_EH1_1	512	520	PF00400	0.217
LIG_eIF4E_1	500	506	PF01652	0.479
LIG_eIF4E_1	513	519	PF01652	0.249
LIG_FHA_1	1063	1069	PF00498	0.309
LIG_FHA_1	15	21	PF00498	0.756
LIG_FHA_1	206	212	PF00498	0.756
LIG_FHA_1	237	243	PF00498	0.764
LIG_FHA_1	382	388	PF00498	0.728
LIG_FHA_1	53	59	PF00498	0.656
LIG_FHA_1	641	647	PF00498	0.841
LIG_FHA_1	683	689	PF00498	0.728
LIG_FHA_1	931	937	PF00498	0.688
LIG_FHA_1	970	976	PF00498	0.455
LIG_FHA_2	27	33	PF00498	0.747
LIG_FHA_2	481	487	PF00498	0.528
LIG_FHA_2	583	589	PF00498	0.638
LIG_FHA_2	727	733	PF00498	0.660
LIG_FHA_2	739	745	PF00498	0.726
LIG_FHA_2	959	965	PF00498	0.399
LIG_Integrin_RGD_1	809	811	PF01839	0.501
LIG_Integrin_RGD_1	883	885	PF01839	0.492
LIG_IRF3_LxIS_1	501	508	PF10401	0.347
LIG_LIR_Apic_2	446	452	PF02991	0.600
LIG_LIR_Gen_1	651	658	PF02991	0.691
LIG_LIR_Gen_1	851	862	PF02991	0.692
LIG_LIR_Nem_3	1052	1057	PF02991	0.217
LIG_LIR_Nem_3	220	226	PF02991	0.682
LIG_LIR_Nem_3	35	41	PF02991	0.688
LIG_LIR_Nem_3	401	407	PF02991	0.631
LIG_LIR_Nem_3	497	503	PF02991	0.504
LIG_LIR_Nem_3	722	726	PF02991	0.728
LIG_LIR_Nem_3	766	771	PF02991	0.748
LIG_LIR_Nem_3	851	857	PF02991	0.712
LIG_LIR_Nem_3	905	910	PF02991	0.661
LIG_MAD2	57	65	PF02301	0.650
LIG_MYND_3	493	497	PF01753	0.478
LIG_NRBOX	438	444	PF00104	0.399
LIG_NRBOX	520	526	PF00104	0.399
LIG_NRBOX	942	948	PF00104	0.583
LIG_Pex14_2	429	433	PF04695	0.262
LIG_Pex14_2	649	653	PF04695	0.626
LIG_Pex14_2	850	854	PF04695	0.677
LIG_Rb_pABgroove_1	860	868	PF01858	0.592
LIG_REV1ctd_RIR_1	81	91	PF16727	0.696
LIG_SH2_CRK	38	42	PF00017	0.717
LIG_SH2_CRK	768	772	PF00017	0.744
LIG_SH2_CRK	866	870	PF00017	0.566
LIG_SH2_NCK_1	407	411	PF00017	0.678
LIG_SH2_NCK_1	530	534	PF00017	0.362
LIG_SH2_NCK_1	554	558	PF00017	0.586
LIG_SH2_SRC	530	533	PF00017	0.362
LIG_SH2_SRC	554	557	PF00017	0.583
LIG_SH2_SRC	910	913	PF00017	0.672
LIG_SH2_SRC	942	945	PF00017	0.616
LIG_SH2_STAP1	341	345	PF00017	0.647
LIG_SH2_STAP1	706	710	PF00017	0.713
LIG_SH2_STAT3	320	323	PF00017	0.670
LIG_SH2_STAT5	159	162	PF00017	0.728
LIG_SH2_STAT5	320	323	PF00017	0.710
LIG_SH2_STAT5	422	425	PF00017	0.629
LIG_SH2_STAT5	453	456	PF00017	0.501
LIG_SH2_STAT5	910	913	PF00017	0.744
LIG_SH2_STAT5	942	945	PF00017	0.616
LIG_SH3_3	224	230	PF00018	0.764
LIG_SH3_3	318	324	PF00018	0.675
LIG_SH3_3	444	450	PF00018	0.586
LIG_SH3_3	481	487	PF00018	0.401
LIG_SH3_3	567	573	PF00018	0.686
LIG_SH3_3	601	607	PF00018	0.693
LIG_SH3_3	825	831	PF00018	0.648
LIG_SH3_3	932	938	PF00018	0.683
LIG_SH3_3	94	100	PF00018	0.761
LIG_SH3_3	998	1004	PF00018	0.527
LIG_SH3_CIN85_PxpxPR_1	124	129	PF14604	0.710
LIG_Sin3_3	468	475	PF02671	0.449
LIG_SUMO_SIM_anti_2	438	444	PF11976	0.399
LIG_SUMO_SIM_anti_2	469	475	PF11976	0.448
LIG_SUMO_SIM_anti_2	972	977	PF11976	0.439
LIG_SUMO_SIM_par_1	441	446	PF11976	0.399
LIG_SUMO_SIM_par_1	522	528	PF11976	0.399
LIG_TRAF2_1	483	486	PF00917	0.412
LIG_TYR_ITIM	940	945	PF00017	0.566
LIG_Vh1_VBS_1	1056	1074	PF01044	0.374
MOD_CDK_SPK_2	754	759	PF00069	0.744
MOD_CDK_SPxxK_3	754	761	PF00069	0.647
MOD_CK1_1	1016	1022	PF00069	0.490
MOD_CK1_1	183	189	PF00069	0.715
MOD_CK1_1	23	29	PF00069	0.806
MOD_CK1_1	231	237	PF00069	0.753
MOD_CK1_1	31	37	PF00069	0.772
MOD_CK1_1	394	400	PF00069	0.573
MOD_CK1_1	438	444	PF00069	0.287
MOD_CK1_1	466	472	PF00069	0.475
MOD_CK1_1	583	589	PF00069	0.774
MOD_CK1_1	617	623	PF00069	0.733
MOD_CK1_1	782	788	PF00069	0.766
MOD_CK1_1	924	930	PF00069	0.703
MOD_CK1_1	983	989	PF00069	0.467
MOD_CK1_1	992	998	PF00069	0.473
MOD_CK2_1	480	486	PF00069	0.391
MOD_CK2_1	533	539	PF00069	0.597
MOD_CK2_1	738	744	PF00069	0.738
MOD_CK2_1	754	760	PF00069	0.651
MOD_CK2_1	835	841	PF00069	0.730
MOD_CK2_1	958	964	PF00069	0.399
MOD_GlcNHglycan	1015	1018	PF01048	0.616
MOD_GlcNHglycan	1019	1022	PF01048	0.714
MOD_GlcNHglycan	1031	1034	PF01048	0.593
MOD_GlcNHglycan	1047	1052	PF01048	0.667
MOD_GlcNHglycan	110	113	PF01048	0.577
MOD_GlcNHglycan	124	127	PF01048	0.490
MOD_GlcNHglycan	176	179	PF01048	0.519
MOD_GlcNHglycan	182	185	PF01048	0.549
MOD_GlcNHglycan	233	236	PF01048	0.553
MOD_GlcNHglycan	291	294	PF01048	0.517
MOD_GlcNHglycan	370	373	PF01048	0.511
MOD_GlcNHglycan	389	392	PF01048	0.401
MOD_GlcNHglycan	393	396	PF01048	0.462
MOD_GlcNHglycan	465	468	PF01048	0.749
MOD_GlcNHglycan	480	483	PF01048	0.607
MOD_GlcNHglycan	628	631	PF01048	0.567
MOD_GlcNHglycan	637	640	PF01048	0.541
MOD_GlcNHglycan	661	664	PF01048	0.491
MOD_GlcNHglycan	681	685	PF01048	0.520
MOD_GlcNHglycan	750	753	PF01048	0.442
MOD_GlcNHglycan	782	785	PF01048	0.563
MOD_GlcNHglycan	844	847	PF01048	0.519
MOD_GlcNHglycan	890	893	PF01048	0.540
MOD_GlcNHglycan	985	988	PF01048	0.708
MOD_GlcNHglycan	997	1000	PF01048	0.633
MOD_GSK3_1	1012	1019	PF00069	0.519
MOD_GSK3_1	176	183	PF00069	0.761
MOD_GSK3_1	20	27	PF00069	0.746
MOD_GSK3_1	381	388	PF00069	0.729
MOD_GSK3_1	394	401	PF00069	0.608
MOD_GSK3_1	53	60	PF00069	0.755
MOD_GSK3_1	580	587	PF00069	0.777
MOD_GSK3_1	688	695	PF00069	0.755
MOD_GSK3_1	700	707	PF00069	0.735
MOD_GSK3_1	750	757	PF00069	0.766
MOD_GSK3_1	772	779	PF00069	0.660
MOD_GSK3_1	884	891	PF00069	0.720
MOD_GSK3_1	92	99	PF00069	0.754
MOD_GSK3_1	989	996	PF00069	0.534
MOD_N-GLC_1	1010	1015	PF02516	0.730
MOD_N-GLC_1	381	386	PF02516	0.481
MOD_N-GLC_1	391	396	PF02516	0.478
MOD_N-GLC_1	478	483	PF02516	0.694
MOD_N-GLC_1	580	585	PF02516	0.559
MOD_N-GLC_1	822	827	PF02516	0.460
MOD_NEK2_1	20	25	PF00069	0.743
MOD_NEK2_1	398	403	PF00069	0.627
MOD_NEK2_1	416	421	PF00069	0.603
MOD_NEK2_1	443	448	PF00069	0.399
MOD_NEK2_1	505	510	PF00069	0.456
MOD_NEK2_1	525	530	PF00069	0.214
MOD_NEK2_1	59	64	PF00069	0.750
MOD_NEK2_1	616	621	PF00069	0.646
MOD_NEK2_1	640	645	PF00069	0.735
MOD_NEK2_1	654	659	PF00069	0.682
MOD_NEK2_1	680	685	PF00069	0.735
MOD_NEK2_1	688	693	PF00069	0.716
MOD_NEK2_1	704	709	PF00069	0.746
MOD_NEK2_1	710	715	PF00069	0.720
MOD_NEK2_1	719	724	PF00069	0.655
MOD_NEK2_1	780	785	PF00069	0.716
MOD_NEK2_1	833	838	PF00069	0.704
MOD_NEK2_1	840	845	PF00069	0.699
MOD_NEK2_1	922	927	PF00069	0.740
MOD_NEK2_1	958	963	PF00069	0.399
MOD_NEK2_2	399	404	PF00069	0.560
MOD_NEK2_2	884	889	PF00069	0.688
MOD_PIKK_1	989	995	PF00454	0.535
MOD_PK_1	580	586	PF00069	0.710
MOD_PKA_1	289	295	PF00069	0.740
MOD_PKA_1	692	698	PF00069	0.634
MOD_PKA_2	1017	1023	PF00069	0.539
MOD_PKA_2	108	114	PF00069	0.665
MOD_PKA_2	174	180	PF00069	0.748
MOD_PKA_2	186	192	PF00069	0.696
MOD_PKA_2	228	234	PF00069	0.755
MOD_PKA_2	399	405	PF00069	0.562
MOD_PKA_2	626	632	PF00069	0.741
MOD_PKA_2	692	698	PF00069	0.634
MOD_PKA_2	704	710	PF00069	0.714
MOD_PKA_2	772	778	PF00069	0.733
MOD_PKA_2	92	98	PF00069	0.725
MOD_PKA_2	993	999	PF00069	0.531
MOD_PKB_1	130	138	PF00069	0.753
MOD_PKB_1	413	421	PF00069	0.606
MOD_PKB_1	698	706	PF00069	0.757
MOD_Plk_1	192	198	PF00069	0.646
MOD_Plk_1	580	586	PF00069	0.701
MOD_Plk_1	822	828	PF00069	0.675
MOD_Plk_1	884	890	PF00069	0.690
MOD_Plk_1	969	975	PF00069	0.483
MOD_Plk_2-3	969	975	PF00069	0.483
MOD_Plk_4	1049	1055	PF00069	0.362
MOD_Plk_4	15	21	PF00069	0.756
MOD_Plk_4	399	405	PF00069	0.562
MOD_Plk_4	435	441	PF00069	0.399
MOD_Plk_4	513	519	PF00069	0.342
MOD_Plk_4	587	593	PF00069	0.689
MOD_Plk_4	617	623	PF00069	0.733
MOD_Plk_4	750	756	PF00069	0.771
MOD_Plk_4	776	782	PF00069	0.643
MOD_Plk_4	835	841	PF00069	0.636
MOD_Plk_4	92	98	PF00069	0.751
MOD_Plk_4	958	964	PF00069	0.362
MOD_Plk_4	980	986	PF00069	0.421
MOD_ProDKin_1	1010	1016	PF00069	0.505
MOD_ProDKin_1	256	262	PF00069	0.663
MOD_ProDKin_1	281	287	PF00069	0.700
MOD_ProDKin_1	480	486	PF00069	0.516
MOD_ProDKin_1	754	760	PF00069	0.760
MOD_ProDKin_1	924	930	PF00069	0.676
MOD_ProDKin_1	96	102	PF00069	0.770
MOD_SUMO_rev_2	300	304	PF00179	0.643
MOD_SUMO_rev_2	561	570	PF00179	0.641
TRG_DiLeu_BaEn_1	776	781	PF01217	0.641
TRG_ENDOCYTIC_2	38	41	PF00928	0.689
TRG_ENDOCYTIC_2	500	503	PF00928	0.482
TRG_ENDOCYTIC_2	768	771	PF00928	0.771
TRG_ENDOCYTIC_2	866	869	PF00928	0.566
TRG_ENDOCYTIC_2	942	945	PF00928	0.616
TRG_ER_diArg_1	127	130	PF00400	0.751
TRG_ER_diArg_1	139	141	PF00400	0.695
TRG_ER_diArg_1	357	360	PF00400	0.766
TRG_ER_diArg_1	412	415	PF00400	0.673
TRG_ER_diArg_1	698	701	PF00400	0.730
TRG_ER_diArg_1	84	87	PF00400	0.722
TRG_NLS_MonoExtN_4	82	89	PF00514	0.696
TRG_Pf-PMV_PEXEL_1	364	369	PF00026	0.382
TRG_Pf-PMV_PEXEL_1	39	43	PF00026	0.487
TRG_Pf-PMV_PEXEL_1	76	80	PF00026	0.489

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H561	Leishmania donovani	82%	99%
A4H3P3	Leishmania braziliensis	53%	100%
A4HRW9	Leishmania infantum	82%	99%
E9ACM6	Leishmania major	80%	99%