Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E9AJT9_LEIMU

TriTrypDb:

LmxM.03.0560

Length:

681

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AJT9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AJT9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	197	201	PF00656	0.646
CLV_C14_Caspase3-7	32	36	PF00656	0.705
CLV_C14_Caspase3-7	634	638	PF00656	0.597
CLV_NRD_NRD_1	159	161	PF00675	0.507
CLV_NRD_NRD_1	219	221	PF00675	0.601
CLV_NRD_NRD_1	25	27	PF00675	0.471
CLV_NRD_NRD_1	276	278	PF00675	0.648
CLV_NRD_NRD_1	307	309	PF00675	0.537
CLV_NRD_NRD_1	317	319	PF00675	0.563
CLV_NRD_NRD_1	359	361	PF00675	0.472
CLV_NRD_NRD_1	39	41	PF00675	0.495
CLV_NRD_NRD_1	408	410	PF00675	0.635
CLV_NRD_NRD_1	492	494	PF00675	0.725
CLV_NRD_NRD_1	53	55	PF00675	0.428
CLV_NRD_NRD_1	533	535	PF00675	0.596
CLV_NRD_NRD_1	672	674	PF00675	0.535
CLV_PCSK_FUR_1	274	278	PF00082	0.519
CLV_PCSK_FUR_1	531	535	PF00082	0.588
CLV_PCSK_KEX2_1	159	161	PF00082	0.516
CLV_PCSK_KEX2_1	219	221	PF00082	0.598
CLV_PCSK_KEX2_1	25	27	PF00082	0.471
CLV_PCSK_KEX2_1	276	278	PF00082	0.644
CLV_PCSK_KEX2_1	307	309	PF00082	0.537
CLV_PCSK_KEX2_1	317	319	PF00082	0.563
CLV_PCSK_KEX2_1	359	361	PF00082	0.472
CLV_PCSK_KEX2_1	39	41	PF00082	0.495
CLV_PCSK_KEX2_1	407	409	PF00082	0.635
CLV_PCSK_KEX2_1	492	494	PF00082	0.725
CLV_PCSK_KEX2_1	53	55	PF00082	0.448
CLV_PCSK_KEX2_1	533	535	PF00082	0.596
CLV_PCSK_KEX2_1	672	674	PF00082	0.535
CLV_PCSK_SKI1_1	105	109	PF00082	0.424
CLV_PCSK_SKI1_1	159	163	PF00082	0.559
CLV_PCSK_SKI1_1	39	43	PF00082	0.533
DEG_ODPH_VHL_1	518	529	PF01847	0.345
DEG_ODPH_VHL_1	602	613	PF01847	0.640
DEG_SPOP_SBC_1	496	500	PF00917	0.549
DOC_CKS1_1	565	570	PF01111	0.690
DOC_CYCLIN_yCln2_LP_2	337	343	PF00134	0.621
DOC_CYCLIN_yCln2_LP_2	389	395	PF00134	0.395
DOC_MAPK_gen_1	149	157	PF00069	0.624
DOC_MAPK_gen_1	672	679	PF00069	0.581
DOC_MAPK_MEF2A_6	149	157	PF00069	0.624
DOC_MAPK_MEF2A_6	600	608	PF00069	0.628
DOC_MAPK_MEF2A_6	614	622	PF00069	0.569
DOC_PP2B_LxvP_1	389	392	PF13499	0.395
DOC_PP2B_LxvP_1	517	520	PF13499	0.395
DOC_PP2B_LxvP_1	622	625	PF13499	0.585
DOC_PP2B_LxvP_1	641	644	PF13499	0.611
DOC_USP7_MATH_1	143	147	PF00917	0.783
DOC_USP7_MATH_1	229	233	PF00917	0.775
DOC_USP7_MATH_1	269	273	PF00917	0.792
DOC_USP7_MATH_1	288	292	PF00917	0.623
DOC_USP7_MATH_1	29	33	PF00917	0.672
DOC_USP7_MATH_1	350	354	PF00917	0.648
DOC_USP7_MATH_1	440	444	PF00917	0.520
DOC_USP7_MATH_1	454	458	PF00917	0.375
DOC_USP7_MATH_1	496	500	PF00917	0.529
DOC_USP7_MATH_1	509	513	PF00917	0.264
DOC_USP7_MATH_1	563	567	PF00917	0.766
DOC_USP7_MATH_1	575	579	PF00917	0.686
DOC_USP7_MATH_1	654	658	PF00917	0.671
DOC_USP7_MATH_1	665	669	PF00917	0.669
DOC_USP7_MATH_1	76	80	PF00917	0.633
DOC_WW_Pin1_4	118	123	PF00397	0.650
DOC_WW_Pin1_4	132	137	PF00397	0.785
DOC_WW_Pin1_4	231	236	PF00397	0.758
DOC_WW_Pin1_4	322	327	PF00397	0.748
DOC_WW_Pin1_4	336	341	PF00397	0.714
DOC_WW_Pin1_4	468	473	PF00397	0.416
DOC_WW_Pin1_4	552	557	PF00397	0.745
DOC_WW_Pin1_4	564	569	PF00397	0.663
DOC_WW_Pin1_4	667	672	PF00397	0.761
DOC_WW_Pin1_4	71	76	PF00397	0.714
LIG_14-3-3_CanoR_1	159	164	PF00244	0.752
LIG_14-3-3_CanoR_1	30	34	PF00244	0.715
LIG_14-3-3_CanoR_1	317	321	PF00244	0.711
LIG_14-3-3_CanoR_1	425	429	PF00244	0.486
LIG_BIR_II_1	1	5	PF00653	0.600
LIG_BRCT_BRCA1_1	312	316	PF00533	0.623
LIG_Clathr_ClatBox_1	395	399	PF01394	0.395
LIG_deltaCOP1_diTrp_1	634	639	PF00928	0.688
LIG_eIF4E_1	254	260	PF01652	0.745
LIG_FHA_1	119	125	PF00498	0.704
LIG_FHA_1	254	260	PF00498	0.687
LIG_FHA_1	386	392	PF00498	0.395
LIG_FHA_1	458	464	PF00498	0.530
LIG_FHA_1	496	502	PF00498	0.419
LIG_FHA_1	664	670	PF00498	0.736
LIG_FHA_1	92	98	PF00498	0.703
LIG_FHA_2	178	184	PF00498	0.642
LIG_FHA_2	9	15	PF00498	0.719
LIG_LIR_Gen_1	379	390	PF02991	0.315
LIG_LIR_Gen_1	579	588	PF02991	0.584
LIG_LIR_Gen_1	594	604	PF02991	0.594
LIG_LIR_Gen_1	7	17	PF02991	0.638
LIG_LIR_Nem_3	166	170	PF02991	0.617
LIG_LIR_Nem_3	249	253	PF02991	0.708
LIG_LIR_Nem_3	297	302	PF02991	0.604
LIG_LIR_Nem_3	379	385	PF02991	0.315
LIG_LIR_Nem_3	579	585	PF02991	0.688
LIG_LIR_Nem_3	594	599	PF02991	0.601
LIG_LIR_Nem_3	610	615	PF02991	0.635
LIG_LIR_Nem_3	7	12	PF02991	0.640
LIG_PCNA_PIPBox_1	605	614	PF02747	0.602
LIG_PCNA_yPIPBox_3	521	534	PF02747	0.491
LIG_PCNA_yPIPBox_3	598	612	PF02747	0.622
LIG_PDZ_Class_2	676	681	PF00595	0.698
LIG_SH2_STAP1	615	619	PF00017	0.610
LIG_SH3_1	236	242	PF00018	0.647
LIG_SH3_3	150	156	PF00018	0.675
LIG_SH3_3	158	164	PF00018	0.826
LIG_SH3_3	236	242	PF00018	0.673
LIG_SH3_3	369	375	PF00018	0.699
LIG_SH3_3	562	568	PF00018	0.690
LIG_SH3_CIN85_PxpxPR_1	235	240	PF14604	0.647
LIG_TRAF2_1	645	648	PF00917	0.795
LIG_TYR_ITIM	613	618	PF00017	0.430
MOD_CDC14_SPxK_1	670	673	PF00782	0.536
MOD_CDK_SPK_2	231	236	PF00069	0.548
MOD_CDK_SPK_2	667	672	PF00069	0.591
MOD_CDK_SPxK_1	667	673	PF00069	0.542
MOD_CDK_SPxxK_3	566	573	PF00069	0.637
MOD_CK1_1	118	124	PF00069	0.578
MOD_CK1_1	130	136	PF00069	0.657
MOD_CK1_1	169	175	PF00069	0.740
MOD_CK1_1	182	188	PF00069	0.595
MOD_CK1_1	272	278	PF00069	0.702
MOD_CK1_1	310	316	PF00069	0.619
MOD_CK1_1	339	345	PF00069	0.648
MOD_CK1_1	346	352	PF00069	0.647
MOD_CK1_1	355	361	PF00069	0.442
MOD_CK1_1	423	429	PF00069	0.622
MOD_CK1_1	457	463	PF00069	0.777
MOD_CK1_1	477	483	PF00069	0.697
MOD_CK1_1	499	505	PF00069	0.618
MOD_CK1_1	566	572	PF00069	0.738
MOD_CK1_1	633	639	PF00069	0.553
MOD_CK1_1	663	669	PF00069	0.556
MOD_CK2_1	355	361	PF00069	0.643
MOD_CK2_1	575	581	PF00069	0.642
MOD_Cter_Amidation	305	308	PF01082	0.562
MOD_Cter_Amidation	51	54	PF01082	0.645
MOD_GlcNHglycan	117	120	PF01048	0.550
MOD_GlcNHglycan	129	132	PF01048	0.619
MOD_GlcNHglycan	145	148	PF01048	0.699
MOD_GlcNHglycan	190	193	PF01048	0.736
MOD_GlcNHglycan	290	293	PF01048	0.619
MOD_GlcNHglycan	31	34	PF01048	0.693
MOD_GlcNHglycan	42	45	PF01048	0.637
MOD_GlcNHglycan	456	459	PF01048	0.662
MOD_GlcNHglycan	476	479	PF01048	0.678
MOD_GlcNHglycan	50	53	PF01048	0.496
MOD_GlcNHglycan	548	552	PF01048	0.521
MOD_GlcNHglycan	55	58	PF01048	0.552
MOD_GlcNHglycan	78	81	PF01048	0.586
MOD_GSK3_1	120	127	PF00069	0.683
MOD_GSK3_1	132	139	PF00069	0.644
MOD_GSK3_1	168	175	PF00069	0.652
MOD_GSK3_1	177	184	PF00069	0.650
MOD_GSK3_1	231	238	PF00069	0.796
MOD_GSK3_1	312	319	PF00069	0.739
MOD_GSK3_1	327	334	PF00069	0.605
MOD_GSK3_1	339	346	PF00069	0.633
MOD_GSK3_1	381	388	PF00069	0.395
MOD_GSK3_1	4	11	PF00069	0.562
MOD_GSK3_1	415	422	PF00069	0.660
MOD_GSK3_1	423	430	PF00069	0.571
MOD_GSK3_1	463	470	PF00069	0.603
MOD_GSK3_1	474	481	PF00069	0.682
MOD_GSK3_1	495	502	PF00069	0.745
MOD_GSK3_1	663	670	PF00069	0.624
MOD_LATS_1	658	664	PF00433	0.562
MOD_N-GLC_1	294	299	PF02516	0.620
MOD_N-GLC_1	310	315	PF02516	0.516
MOD_N-GLC_1	343	348	PF02516	0.488
MOD_N-GLC_1	454	459	PF02516	0.616
MOD_N-GLC_1	654	659	PF02516	0.686
MOD_N-GLC_1	663	668	PF02516	0.587
MOD_NEK2_1	1	6	PF00069	0.483
MOD_NEK2_1	253	258	PF00069	0.614
MOD_NEK2_1	294	299	PF00069	0.620
MOD_NEK2_1	316	321	PF00069	0.616
MOD_NEK2_1	385	390	PF00069	0.350
MOD_NEK2_1	501	506	PF00069	0.474
MOD_NEK2_1	70	75	PF00069	0.561
MOD_NEK2_2	312	317	PF00069	0.527
MOD_PIKK_1	316	322	PF00454	0.610
MOD_PK_1	352	358	PF00069	0.559
MOD_PKA_1	159	165	PF00069	0.510
MOD_PKA_1	307	313	PF00069	0.573
MOD_PKA_1	53	59	PF00069	0.665
MOD_PKA_1	533	539	PF00069	0.781
MOD_PKA_2	127	133	PF00069	0.584
MOD_PKA_2	159	165	PF00069	0.510
MOD_PKA_2	29	35	PF00069	0.686
MOD_PKA_2	307	313	PF00069	0.613
MOD_PKA_2	316	322	PF00069	0.722
MOD_PKA_2	424	430	PF00069	0.643
MOD_PKA_2	478	484	PF00069	0.587
MOD_PKA_2	53	59	PF00069	0.712
MOD_PKA_2	533	539	PF00069	0.781
MOD_PKB_1	531	539	PF00069	0.770
MOD_Plk_1	223	229	PF00069	0.592
MOD_Plk_1	294	300	PF00069	0.622
MOD_Plk_1	310	316	PF00069	0.520
MOD_Plk_1	343	349	PF00069	0.487
MOD_Plk_1	410	416	PF00069	0.632
MOD_Plk_2-3	194	200	PF00069	0.591
MOD_Plk_2-3	8	14	PF00069	0.654
MOD_Plk_4	120	126	PF00069	0.699
MOD_Plk_4	294	300	PF00069	0.672
MOD_Plk_4	381	387	PF00069	0.333
MOD_Plk_4	415	421	PF00069	0.583
MOD_Plk_4	509	515	PF00069	0.348
MOD_Plk_4	554	560	PF00069	0.624
MOD_ProDKin_1	118	124	PF00069	0.558
MOD_ProDKin_1	132	138	PF00069	0.741
MOD_ProDKin_1	231	237	PF00069	0.707
MOD_ProDKin_1	322	328	PF00069	0.690
MOD_ProDKin_1	336	342	PF00069	0.642
MOD_ProDKin_1	468	474	PF00069	0.511
MOD_ProDKin_1	552	558	PF00069	0.690
MOD_ProDKin_1	564	570	PF00069	0.576
MOD_ProDKin_1	667	673	PF00069	0.713
MOD_ProDKin_1	71	77	PF00069	0.648
MOD_SUMO_rev_2	647	652	PF00179	0.616
TRG_ENDOCYTIC_2	582	585	PF00928	0.679
TRG_ENDOCYTIC_2	596	599	PF00928	0.437
TRG_ENDOCYTIC_2	615	618	PF00928	0.582
TRG_ER_diArg_1	148	151	PF00400	0.608
TRG_ER_diArg_1	159	161	PF00400	0.524
TRG_ER_diArg_1	219	221	PF00400	0.719
TRG_ER_diArg_1	24	26	PF00400	0.578
TRG_ER_diArg_1	274	277	PF00400	0.784
TRG_ER_diArg_1	316	318	PF00400	0.675
TRG_ER_diArg_1	406	409	PF00400	0.531
TRG_ER_diArg_1	491	493	PF00400	0.659
TRG_ER_diArg_1	531	534	PF00400	0.747
TRG_ER_diArg_1	671	673	PF00400	0.615
TRG_Pf-PMV_PEXEL_1	219	224	PF00026	0.641
TRG_Pf-PMV_PEXEL_1	40	45	PF00026	0.670
TRG_Pf-PMV_PEXEL_1	600	605	PF00026	0.544

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I4E7	Leptomonas seymouri	28%	98%
A0A3S5H548	Leishmania donovani	81%	95%
A4H3L8	Leishmania braziliensis	58%	100%
E9ACK1	Leishmania major	78%	100%
E9AG45	Leishmania infantum	81%	95%