Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E9AJS9_LEIMU

TriTrypDb:

LmxM.03.0460

Length:

1050

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AJS9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AJS9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	550	554	PF00656	0.651
CLV_C14_Caspase3-7	90	94	PF00656	0.783
CLV_C14_Caspase3-7	966	970	PF00656	0.598
CLV_NRD_NRD_1	1025	1027	PF00675	0.539
CLV_NRD_NRD_1	126	128	PF00675	0.758
CLV_NRD_NRD_1	171	173	PF00675	0.563
CLV_NRD_NRD_1	205	207	PF00675	0.837
CLV_NRD_NRD_1	634	636	PF00675	0.542
CLV_NRD_NRD_1	915	917	PF00675	0.782
CLV_PCSK_FUR_1	632	636	PF00082	0.570
CLV_PCSK_FUR_1	913	917	PF00082	0.778
CLV_PCSK_KEX2_1	1025	1027	PF00082	0.544
CLV_PCSK_KEX2_1	126	128	PF00082	0.758
CLV_PCSK_KEX2_1	171	173	PF00082	0.563
CLV_PCSK_KEX2_1	205	207	PF00082	0.842
CLV_PCSK_KEX2_1	634	636	PF00082	0.542
CLV_PCSK_KEX2_1	915	917	PF00082	0.782
CLV_PCSK_PC7_1	201	207	PF00082	0.871
CLV_PCSK_SKI1_1	139	143	PF00082	0.855
CLV_PCSK_SKI1_1	172	176	PF00082	0.700
CLV_PCSK_SKI1_1	552	556	PF00082	0.828
CLV_PCSK_SKI1_1	564	568	PF00082	0.614
CLV_PCSK_SKI1_1	659	663	PF00082	0.624
CLV_PCSK_SKI1_1	915	919	PF00082	0.778
CLV_PCSK_SKI1_1	961	965	PF00082	0.509
CLV_PCSK_SKI1_1	997	1001	PF00082	0.722
DEG_Nend_Nbox_1	1	3	PF02207	0.792
DEG_SPOP_SBC_1	572	576	PF00917	0.721
DOC_CKS1_1	234	239	PF01111	0.859
DOC_CKS1_1	450	455	PF01111	0.797
DOC_CKS1_1	457	462	PF01111	0.763
DOC_CKS1_1	536	541	PF01111	0.812
DOC_CKS1_1	781	786	PF01111	0.815
DOC_CYCLIN_RxL_1	136	146	PF00134	0.848
DOC_CYCLIN_yCln2_LP_2	114	120	PF00134	0.570
DOC_CYCLIN_yCln2_LP_2	292	298	PF00134	0.485
DOC_MAPK_gen_1	205	216	PF00069	0.777
DOC_MAPK_MEF2A_6	209	218	PF00069	0.769
DOC_PP2B_LxvP_1	1000	1003	PF13499	0.788
DOC_PP2B_LxvP_1	132	135	PF13499	0.850
DOC_PP2B_LxvP_1	255	258	PF13499	0.735
DOC_PP2B_LxvP_1	486	489	PF13499	0.658
DOC_PP4_FxxP_1	100	103	PF00568	0.559
DOC_PP4_MxPP_1	245	248	PF00568	0.737
DOC_USP7_MATH_1	1009	1013	PF00917	0.493
DOC_USP7_MATH_1	137	141	PF00917	0.741
DOC_USP7_MATH_1	272	276	PF00917	0.848
DOC_USP7_MATH_1	523	527	PF00917	0.824
DOC_USP7_MATH_1	571	575	PF00917	0.744
DOC_USP7_MATH_1	594	598	PF00917	0.657
DOC_USP7_MATH_1	625	629	PF00917	0.798
DOC_USP7_MATH_1	683	687	PF00917	0.772
DOC_USP7_MATH_1	694	698	PF00917	0.722
DOC_WW_Pin1_4	109	114	PF00397	0.690
DOC_WW_Pin1_4	141	146	PF00397	0.555
DOC_WW_Pin1_4	233	238	PF00397	0.863
DOC_WW_Pin1_4	28	33	PF00397	0.811
DOC_WW_Pin1_4	334	339	PF00397	0.723
DOC_WW_Pin1_4	368	373	PF00397	0.575
DOC_WW_Pin1_4	384	389	PF00397	0.535
DOC_WW_Pin1_4	399	404	PF00397	0.596
DOC_WW_Pin1_4	423	428	PF00397	0.793
DOC_WW_Pin1_4	445	450	PF00397	0.834
DOC_WW_Pin1_4	456	461	PF00397	0.634
DOC_WW_Pin1_4	502	507	PF00397	0.777
DOC_WW_Pin1_4	512	517	PF00397	0.673
DOC_WW_Pin1_4	535	540	PF00397	0.813
DOC_WW_Pin1_4	678	683	PF00397	0.737
DOC_WW_Pin1_4	690	695	PF00397	0.664
DOC_WW_Pin1_4	699	704	PF00397	0.681
DOC_WW_Pin1_4	719	724	PF00397	0.521
DOC_WW_Pin1_4	760	765	PF00397	0.778
DOC_WW_Pin1_4	780	785	PF00397	0.813
DOC_WW_Pin1_4	797	802	PF00397	0.551
DOC_WW_Pin1_4	840	845	PF00397	0.805
DOC_WW_Pin1_4	860	865	PF00397	0.842
DOC_WW_Pin1_4	986	991	PF00397	0.670
DOC_WW_Pin1_4	99	104	PF00397	0.841
LIG_14-3-3_CanoR_1	1025	1029	PF00244	0.535
LIG_14-3-3_CanoR_1	1038	1044	PF00244	0.596
LIG_14-3-3_CanoR_1	11	18	PF00244	0.635
LIG_14-3-3_CanoR_1	126	136	PF00244	0.860
LIG_14-3-3_CanoR_1	139	144	PF00244	0.524
LIG_14-3-3_CanoR_1	171	181	PF00244	0.552
LIG_14-3-3_CanoR_1	209	215	PF00244	0.559
LIG_14-3-3_CanoR_1	375	383	PF00244	0.628
LIG_14-3-3_CanoR_1	433	438	PF00244	0.836
LIG_14-3-3_CanoR_1	587	596	PF00244	0.731
LIG_14-3-3_CanoR_1	659	665	PF00244	0.618
LIG_14-3-3_CanoR_1	687	696	PF00244	0.722
LIG_14-3-3_CanoR_1	739	747	PF00244	0.761
LIG_Actin_WH2_2	281	299	PF00022	0.514
LIG_BIR_III_4	190	194	PF00653	0.552
LIG_BIR_III_4	771	775	PF00653	0.719
LIG_deltaCOP1_diTrp_1	796	804	PF00928	0.670
LIG_EVH1_1	132	136	PF00568	0.846
LIG_FHA_1	10	16	PF00498	0.669
LIG_FHA_1	162	168	PF00498	0.797
LIG_FHA_1	371	377	PF00498	0.665
LIG_FHA_1	378	384	PF00498	0.786
LIG_FHA_1	536	542	PF00498	0.815
LIG_FHA_1	62	68	PF00498	0.551
LIG_FHA_1	650	656	PF00498	0.709
LIG_FHA_1	720	726	PF00498	0.808
LIG_FHA_1	846	852	PF00498	0.529
LIG_FHA_1	883	889	PF00498	0.832
LIG_FHA_1	954	960	PF00498	0.590
LIG_FHA_2	234	240	PF00498	0.779
LIG_FHA_2	503	509	PF00498	0.809
LIG_FHA_2	548	554	PF00498	0.742
LIG_Integrin_RGD_1	967	969	PF01839	0.601
LIG_LIR_Apic_2	399	403	PF02991	0.784
LIG_LIR_Apic_2	697	703	PF02991	0.804
LIG_LIR_Apic_2	796	801	PF02991	0.831
LIG_LIR_Apic_2	99	103	PF02991	0.563
LIG_LIR_Gen_1	896	904	PF02991	0.722
LIG_LIR_Nem_3	249	253	PF02991	0.727
LIG_LIR_Nem_3	300	306	PF02991	0.777
LIG_LIR_Nem_3	627	633	PF02991	0.694
LIG_LIR_Nem_3	843	849	PF02991	0.701
LIG_LIR_Nem_3	896	900	PF02991	0.725
LIG_LYPXL_yS_3	846	849	PF13949	0.532
LIG_MYND_1	318	322	PF01753	0.573
LIG_NRBOX	897	903	PF00104	0.718
LIG_PTAP_UEV_1	712	717	PF05743	0.537
LIG_SH2_NCK_1	650	654	PF00017	0.530
LIG_SH2_STAP1	650	654	PF00017	0.530
LIG_SH2_STAT3	701	704	PF00017	0.807
LIG_SH2_STAT5	323	326	PF00017	0.572
LIG_SH2_STAT5	630	633	PF00017	0.690
LIG_SH3_1	231	237	PF00018	0.667
LIG_SH3_1	35	41	PF00018	0.788
LIG_SH3_3	105	111	PF00018	0.690
LIG_SH3_3	130	136	PF00018	0.797
LIG_SH3_3	231	237	PF00018	0.745
LIG_SH3_3	302	308	PF00018	0.782
LIG_SH3_3	35	41	PF00018	0.749
LIG_SH3_3	447	453	PF00018	0.743
LIG_SH3_3	454	460	PF00018	0.828
LIG_SH3_3	465	471	PF00018	0.545
LIG_SH3_3	710	716	PF00018	0.536
LIG_SH3_3	720	726	PF00018	0.538
LIG_SH3_3	80	86	PF00018	0.670
LIG_SH3_3	841	847	PF00018	0.524
LIG_SH3_3	984	990	PF00018	0.718
LIG_SUMO_SIM_anti_2	835	841	PF11976	0.508
LIG_SUMO_SIM_anti_2	896	902	PF11976	0.720
LIG_SUMO_SIM_par_1	538	544	PF11976	0.525
LIG_SUMO_SIM_par_1	838	843	PF11976	0.525
LIG_SUMO_SIM_par_1	847	853	PF11976	0.593
LIG_SUMO_SIM_par_1	884	889	PF11976	0.828
LIG_TRAF2_1	185	188	PF00917	0.827
LIG_TRAF2_1	492	495	PF00917	0.697
LIG_TRAF2_2	806	811	PF00917	0.777
LIG_UBA3_1	292	297	PF00899	0.780
LIG_WRC_WIRS_1	488	493	PF05994	0.486
LIG_WW_1	247	250	PF00397	0.726
LIG_WW_1	85	88	PF00397	0.854
LIG_WW_3	36	40	PF00397	0.574
MOD_CDC14_SPxK_1	36	39	PF00782	0.572
MOD_CDK_SPK_2	104	109	PF00069	0.775
MOD_CDK_SPK_2	334	339	PF00069	0.663
MOD_CDK_SPK_2	456	461	PF00069	0.784
MOD_CDK_SPxK_1	33	39	PF00069	0.580
MOD_CDK_SPxK_1	449	455	PF00069	0.797
MOD_CDK_SPxK_1	760	766	PF00069	0.781
MOD_CDK_SPxxK_3	28	35	PF00069	0.732
MOD_CDK_SPxxK_3	368	375	PF00069	0.810
MOD_CDK_SPxxK_3	99	106	PF00069	0.779
MOD_CK1_1	277	283	PF00069	0.782
MOD_CK1_1	30	36	PF00069	0.756
MOD_CK1_1	448	454	PF00069	0.691
MOD_CK1_1	487	493	PF00069	0.674
MOD_CK1_1	592	598	PF00069	0.643
MOD_CK1_1	681	687	PF00069	0.811
MOD_CK1_1	690	696	PF00069	0.653
MOD_CK1_1	745	751	PF00069	0.755
MOD_CK1_1	838	844	PF00069	0.702
MOD_CK1_1	845	851	PF00069	0.753
MOD_CK1_1	882	888	PF00069	0.735
MOD_CK1_1	89	95	PF00069	0.708
MOD_CK1_1	985	991	PF00069	0.810
MOD_CK2_1	353	359	PF00069	0.742
MOD_CK2_1	502	508	PF00069	0.808
MOD_CK2_1	868	874	PF00069	0.836
MOD_CK2_1	93	99	PF00069	0.780
MOD_GlcNHglycan	1011	1014	PF01048	0.680
MOD_GlcNHglycan	1039	1042	PF01048	0.713
MOD_GlcNHglycan	355	358	PF01048	0.762
MOD_GlcNHglycan	393	396	PF01048	0.715
MOD_GlcNHglycan	569	572	PF01048	0.726
MOD_GlcNHglycan	592	595	PF01048	0.743
MOD_GlcNHglycan	596	599	PF01048	0.803
MOD_GlcNHglycan	627	630	PF01048	0.793
MOD_GlcNHglycan	713	716	PF01048	0.747
MOD_GlcNHglycan	751	754	PF01048	0.663
MOD_GlcNHglycan	785	788	PF01048	0.764
MOD_GlcNHglycan	910	913	PF01048	0.735
MOD_GlcNHglycan	95	98	PF01048	0.686
MOD_GlcNHglycan	969	973	PF01048	0.703
MOD_GlcNHglycan	984	987	PF01048	0.625
MOD_GSK3_1	109	116	PF00069	0.761
MOD_GSK3_1	137	144	PF00069	0.776
MOD_GSK3_1	205	212	PF00069	0.656
MOD_GSK3_1	272	279	PF00069	0.837
MOD_GSK3_1	351	358	PF00069	0.670
MOD_GSK3_1	422	429	PF00069	0.834
MOD_GSK3_1	433	440	PF00069	0.722
MOD_GSK3_1	445	452	PF00069	0.614
MOD_GSK3_1	537	544	PF00069	0.528
MOD_GSK3_1	556	563	PF00069	0.642
MOD_GSK3_1	567	574	PF00069	0.656
MOD_GSK3_1	585	592	PF00069	0.561
MOD_GSK3_1	6	13	PF00069	0.735
MOD_GSK3_1	683	690	PF00069	0.789
MOD_GSK3_1	695	702	PF00069	0.574
MOD_GSK3_1	711	718	PF00069	0.684
MOD_GSK3_1	738	745	PF00069	0.671
MOD_GSK3_1	779	786	PF00069	0.754
MOD_GSK3_1	838	845	PF00069	0.682
MOD_GSK3_1	89	96	PF00069	0.720
MOD_GSK3_1	943	950	PF00069	0.543
MOD_GSK3_1	982	989	PF00069	0.772
MOD_LATS_1	125	131	PF00433	0.873
MOD_LATS_1	203	209	PF00433	0.870
MOD_LATS_1	866	872	PF00433	0.756
MOD_N-GLC_1	731	736	PF02516	0.544
MOD_N-GLC_1	908	913	PF02516	0.729
MOD_NEK2_1	10	15	PF00069	0.701
MOD_NEK2_1	391	396	PF00069	0.659
MOD_NEK2_1	405	410	PF00069	0.500
MOD_NEK2_1	432	437	PF00069	0.840
MOD_NEK2_1	555	560	PF00069	0.824
MOD_NEK2_1	567	572	PF00069	0.607
MOD_NEK2_1	590	595	PF00069	0.517
MOD_NEK2_1	623	628	PF00069	0.800
MOD_NEK2_1	765	770	PF00069	0.710
MOD_NEK2_2	428	433	PF00069	0.549
MOD_PIKK_1	277	283	PF00454	0.841
MOD_PIKK_1	742	748	PF00454	0.836
MOD_PIKK_1	879	885	PF00454	0.849
MOD_PK_1	433	439	PF00069	0.836
MOD_PKA_1	205	211	PF00069	0.836
MOD_PKA_2	10	16	PF00069	0.645
MOD_PKA_2	1024	1030	PF00069	0.545
MOD_PKA_2	1037	1043	PF00069	0.636
MOD_PKA_2	128	134	PF00069	0.863
MOD_PKA_2	204	210	PF00069	0.831
MOD_PKA_2	3	9	PF00069	0.627
MOD_PKA_2	376	382	PF00069	0.531
MOD_PKA_2	432	438	PF00069	0.837
MOD_PKA_2	586	592	PF00069	0.728
MOD_PKA_2	738	744	PF00069	0.763
MOD_PKA_2	765	771	PF00069	0.710
MOD_PKB_1	375	383	PF00069	0.531
MOD_Plk_1	731	737	PF00069	0.544
MOD_Plk_1	877	883	PF00069	0.798
MOD_Plk_2-3	884	890	PF00069	0.527
MOD_Plk_4	378	384	PF00069	0.547
MOD_Plk_4	515	521	PF00069	0.537
MOD_Plk_4	537	543	PF00069	0.814
MOD_Plk_4	577	583	PF00069	0.520
MOD_Plk_4	695	701	PF00069	0.724
MOD_Plk_4	835	841	PF00069	0.581
MOD_Plk_4	949	955	PF00069	0.682
MOD_ProDKin_1	109	115	PF00069	0.689
MOD_ProDKin_1	141	147	PF00069	0.554
MOD_ProDKin_1	233	239	PF00069	0.862
MOD_ProDKin_1	28	34	PF00069	0.812
MOD_ProDKin_1	334	340	PF00069	0.721
MOD_ProDKin_1	368	374	PF00069	0.574
MOD_ProDKin_1	384	390	PF00069	0.535
MOD_ProDKin_1	399	405	PF00069	0.598
MOD_ProDKin_1	423	429	PF00069	0.793
MOD_ProDKin_1	445	451	PF00069	0.837
MOD_ProDKin_1	456	462	PF00069	0.634
MOD_ProDKin_1	502	508	PF00069	0.808
MOD_ProDKin_1	512	518	PF00069	0.673
MOD_ProDKin_1	535	541	PF00069	0.811
MOD_ProDKin_1	678	684	PF00069	0.740
MOD_ProDKin_1	690	696	PF00069	0.662
MOD_ProDKin_1	699	705	PF00069	0.680
MOD_ProDKin_1	719	725	PF00069	0.522
MOD_ProDKin_1	760	766	PF00069	0.781
MOD_ProDKin_1	780	786	PF00069	0.814
MOD_ProDKin_1	797	803	PF00069	0.551
MOD_ProDKin_1	840	846	PF00069	0.806
MOD_ProDKin_1	860	866	PF00069	0.843
MOD_ProDKin_1	986	992	PF00069	0.667
MOD_ProDKin_1	99	105	PF00069	0.841
TRG_DiLeu_BaEn_1	896	901	PF01217	0.722
TRG_ENDOCYTIC_2	846	849	PF00928	0.745
TRG_ER_diArg_1	1024	1026	PF00400	0.622
TRG_ER_diArg_1	1029	1032	PF00400	0.680
TRG_ER_diArg_1	1036	1039	PF00400	0.583
TRG_ER_diArg_1	126	128	PF00400	0.875
TRG_ER_diArg_1	171	173	PF00400	0.566
TRG_ER_diArg_1	374	377	PF00400	0.542
TRG_ER_diArg_1	633	635	PF00400	0.590
TRG_ER_diArg_1	913	916	PF00400	0.776
TRG_Pf-PMV_PEXEL_1	916	920	PF00026	0.779

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A451EJP7	Leishmania donovani	78%	99%
A4H3R6	Leishmania braziliensis	59%	97%
E9ACJ1	Leishmania major	79%	100%
E9AG35	Leishmania infantum	77%	99%