These Kinetoplastid-specific proteins have an unclear topology and structure. Might not be even embedded into the membrane.
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 10 |
| NetGPI | no | yes: 0, no: 10 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0016020 | membrane | 2 | 1 |
| GO:0110165 | cellular anatomical entity | 1 | 1 |
Related structures:
AlphaFold database: E9AJQ9
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_NRD_NRD_1 | 21 | 23 | PF00675 | 0.482 |
| CLV_NRD_NRD_1 | 77 | 79 | PF00675 | 0.401 |
| CLV_PCSK_FUR_1 | 19 | 23 | PF00082 | 0.466 |
| CLV_PCSK_KEX2_1 | 143 | 145 | PF00082 | 0.556 |
| CLV_PCSK_KEX2_1 | 19 | 21 | PF00082 | 0.487 |
| CLV_PCSK_KEX2_1 | 77 | 79 | PF00082 | 0.401 |
| CLV_PCSK_PC1ET2_1 | 143 | 145 | PF00082 | 0.534 |
| CLV_PCSK_SKI1_1 | 21 | 25 | PF00082 | 0.269 |
| DOC_CYCLIN_RxL_1 | 18 | 26 | PF00134 | 0.615 |
| DOC_PP2B_LxvP_1 | 112 | 115 | PF13499 | 0.652 |
| DOC_PP4_FxxP_1 | 44 | 47 | PF00568 | 0.416 |
| DOC_USP7_MATH_1 | 137 | 141 | PF00917 | 0.731 |
| LIG_14-3-3_CanoR_1 | 120 | 128 | PF00244 | 0.707 |
| LIG_BIR_III_4 | 26 | 30 | PF00653 | 0.447 |
| LIG_eIF4E_1 | 59 | 65 | PF01652 | 0.408 |
| LIG_FHA_1 | 88 | 94 | PF00498 | 0.753 |
| LIG_LIR_Apic_2 | 42 | 47 | PF02991 | 0.418 |
| LIG_LIR_Gen_1 | 108 | 117 | PF02991 | 0.671 |
| LIG_LIR_Nem_3 | 108 | 114 | PF02991 | 0.688 |
| LIG_NRBOX | 32 | 38 | PF00104 | 0.434 |
| LIG_PCNA_yPIPBox_3 | 30 | 38 | PF02747 | 0.214 |
| LIG_Rb_pABgroove_1 | 35 | 43 | PF01858 | 0.480 |
| LIG_SH2_CRK | 61 | 65 | PF00017 | 0.319 |
| LIG_SH2_NCK_1 | 25 | 29 | PF00017 | 0.378 |
| LIG_SH2_STAT5 | 98 | 101 | PF00017 | 0.694 |
| LIG_SH3_4 | 101 | 108 | PF00018 | 0.658 |
| LIG_TRAF2_1 | 69 | 72 | PF00917 | 0.710 |
| LIG_UBA3_1 | 36 | 45 | PF00899 | 0.685 |
| MOD_CK1_1 | 129 | 135 | PF00069 | 0.734 |
| MOD_CK1_1 | 4 | 10 | PF00069 | 0.767 |
| MOD_CK1_1 | 83 | 89 | PF00069 | 0.551 |
| MOD_CK2_1 | 66 | 72 | PF00069 | 0.663 |
| MOD_Cter_Amidation | 75 | 78 | PF01082 | 0.424 |
| MOD_GlcNHglycan | 133 | 136 | PF01048 | 0.513 |
| MOD_GlcNHglycan | 6 | 9 | PF01048 | 0.534 |
| MOD_GSK3_1 | 122 | 129 | PF00069 | 0.689 |
| MOD_GSK3_1 | 83 | 90 | PF00069 | 0.549 |
| MOD_NEK2_1 | 1 | 6 | PF00069 | 0.788 |
| MOD_PKA_2 | 4 | 10 | PF00069 | 0.759 |
| MOD_PKA_2 | 87 | 93 | PF00069 | 0.665 |
| MOD_Plk_1 | 129 | 135 | PF00069 | 0.752 |
| MOD_SUMO_rev_2 | 140 | 145 | PF00179 | 0.729 |
| MOD_SUMO_rev_2 | 42 | 47 | PF00179 | 0.498 |
| TRG_DiLeu_BaLyEn_6 | 19 | 24 | PF01217 | 0.617 |
| TRG_ENDOCYTIC_2 | 41 | 44 | PF00928 | 0.464 |
| TRG_ENDOCYTIC_2 | 61 | 64 | PF00928 | 0.150 |
| TRG_ER_diArg_1 | 19 | 22 | PF00400 | 0.681 |
| TRG_ER_diArg_1 | 77 | 79 | PF00400 | 0.629 |
| TRG_Pf-PMV_PEXEL_1 | 104 | 108 | PF00026 | 0.511 |
| TRG_Pf-PMV_PEXEL_1 | 21 | 26 | PF00026 | 0.289 |
| TRG_Pf-PMV_PEXEL_1 | 77 | 82 | PF00026 | 0.381 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N0P4K8 | Leptomonas seymouri | 72% | 94% |
| A0A0S4JRA9 | Bodo saltans | 43% | 95% |
| A0A1X0P915 | Trypanosomatidae | 49% | 94% |
| A0A422NQR6 | Trypanosoma rangeli | 53% | 94% |
| A0A451EJM8 | Leishmania donovani | 93% | 94% |
| A4H3J6 | Leishmania braziliensis | 84% | 100% |
| A4HRT5 | Leishmania infantum | 94% | 94% |
| D0A236 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 47% | 94% |
| E9ACH1 | Leishmania major | 93% | 100% |