Protein kinase domain-containing protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

protein kinase, putative

Species:

Leishmania mexicana

UniProt:

E9AJQ6_LEIMU

TriTrypDb:

LmxM.03.0210

Length:

287

Annotations

LeishMANIAdb annotations

Acyltransferase involved in GPI anchor remodelling (homologue of yeast GUP1)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0005737	cytoplasm	2	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9AJQ6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AJQ6

Function

Biological processes
Term	Name	Level	Count
GO:0006468	protein phosphorylation	5	12
GO:0006793	phosphorus metabolic process	3	12
GO:0006796	phosphate-containing compound metabolic process	4	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0016310	phosphorylation	5	12
GO:0019538	protein metabolic process	3	12
GO:0036211	protein modification process	4	12
GO:0043170	macromolecule metabolic process	3	12
GO:0043412	macromolecule modification	4	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0071704	organic substance metabolic process	2	12
GO:1901564	organonitrogen compound metabolic process	3	12
GO:0007165	signal transduction	2	1
GO:0035556	intracellular signal transduction	3	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0065007	biological regulation	1	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003824	catalytic activity	1	12
GO:0004672	protein kinase activity	3	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0016301	kinase activity	4	12
GO:0016740	transferase activity	2	12
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	12
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140096	catalytic activity, acting on a protein	2	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12
GO:0004674	protein serine/threonine kinase activity	4	1
GO:0004707	MAP kinase activity	5	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	117	119	PF00675	0.307
CLV_NRD_NRD_1	170	172	PF00675	0.298
CLV_PCSK_KEX2_1	117	119	PF00082	0.317
CLV_PCSK_KEX2_1	170	172	PF00082	0.302
CLV_PCSK_KEX2_1	213	215	PF00082	0.386
CLV_PCSK_KEX2_1	261	263	PF00082	0.515
CLV_PCSK_PC1ET2_1	213	215	PF00082	0.363
CLV_PCSK_PC1ET2_1	261	263	PF00082	0.515
CLV_PCSK_SKI1_1	118	122	PF00082	0.301
CLV_PCSK_SKI1_1	144	148	PF00082	0.383
CLV_PCSK_SKI1_1	25	29	PF00082	0.326
CLV_PCSK_SKI1_1	51	55	PF00082	0.301
DEG_Nend_UBRbox_2	1	3	PF02207	0.157
DOC_CDC14_PxL_1	181	189	PF14671	0.358
DOC_CDC14_PxL_1	192	200	PF14671	0.358
DOC_CKS1_1	139	144	PF01111	0.317
DOC_CYCLIN_RxL_1	115	125	PF00134	0.358
DOC_MAPK_gen_1	261	269	PF00069	0.531
DOC_PP4_FxxP_1	71	74	PF00568	0.301
DOC_USP7_MATH_1	122	126	PF00917	0.324
DOC_USP7_MATH_1	149	153	PF00917	0.343
DOC_USP7_MATH_1	172	176	PF00917	0.412
DOC_USP7_MATH_1	283	287	PF00917	0.702
DOC_USP7_MATH_2	74	80	PF00917	0.301
DOC_WW_Pin1_4	138	143	PF00397	0.288
LIG_14-3-3_CanoR_1	155	163	PF00244	0.314
LIG_14-3-3_CanoR_1	25	33	PF00244	0.336
LIG_APCC_ABBA_1	267	272	PF00400	0.509
LIG_BRCT_BRCA1_1	58	62	PF00533	0.308
LIG_BRCT_BRCA1_1	68	72	PF00533	0.287
LIG_Clathr_ClatBox_1	206	210	PF01394	0.386
LIG_eIF4E_1	26	32	PF01652	0.317
LIG_FHA_1	181	187	PF00498	0.356
LIG_FHA_1	26	32	PF00498	0.336
LIG_FHA_1	48	54	PF00498	0.317
LIG_FHA_2	16	22	PF00498	0.436
LIG_GBD_Chelix_1	198	206	PF00786	0.189
LIG_GBD_Chelix_1	23	31	PF00786	0.392
LIG_LIR_Apic_2	69	74	PF02991	0.301
LIG_LIR_Apic_2	84	90	PF02991	0.301
LIG_LIR_Nem_3	79	83	PF02991	0.301
LIG_MLH1_MIPbox_1	68	72	PF16413	0.278
LIG_NRBOX	110	116	PF00104	0.386
LIG_NRBOX	176	182	PF00104	0.336
LIG_PCNA_yPIPBox_3	253	262	PF02747	0.582
LIG_Pex14_2	62	66	PF04695	0.317
LIG_SH2_NCK_1	163	167	PF00017	0.421
LIG_SH2_SRC	3	6	PF00017	0.386
LIG_SH2_STAP1	100	104	PF00017	0.389
LIG_SH2_STAP1	163	167	PF00017	0.301
LIG_SH2_STAT3	57	60	PF00017	0.336
LIG_SH2_STAT5	167	170	PF00017	0.358
LIG_SH2_STAT5	26	29	PF00017	0.301
LIG_SH2_STAT5	3	6	PF00017	0.300
LIG_SH3_3	136	142	PF00018	0.317
MOD_CDK_SPxK_1	138	144	PF00069	0.386
MOD_CK1_1	125	131	PF00069	0.333
MOD_CK1_1	99	105	PF00069	0.421
MOD_CK2_1	15	21	PF00069	0.421
MOD_CK2_1	213	219	PF00069	0.336
MOD_GlcNHglycan	127	130	PF01048	0.317
MOD_GlcNHglycan	215	218	PF01048	0.421
MOD_GSK3_1	15	22	PF00069	0.349
MOD_GSK3_1	99	106	PF00069	0.421
MOD_N-GLC_1	125	130	PF02516	0.317
MOD_NEK2_1	180	185	PF00069	0.386
MOD_NEK2_1	187	192	PF00069	0.386
MOD_NEK2_1	19	24	PF00069	0.405
MOD_NEK2_1	248	253	PF00069	0.562
MOD_NEK2_1	66	71	PF00069	0.301
MOD_PIKK_1	154	160	PF00454	0.416
MOD_PIKK_1	246	252	PF00454	0.621
MOD_PIKK_1	56	62	PF00454	0.301
MOD_PIKK_1	81	87	PF00454	0.301
MOD_PKA_1	213	219	PF00069	0.421
MOD_PKA_2	154	160	PF00069	0.301
MOD_PKA_2	213	219	PF00069	0.291
MOD_Plk_1	149	155	PF00069	0.421
MOD_Plk_1	19	25	PF00069	0.284
MOD_Plk_1	6	12	PF00069	0.308
MOD_Plk_4	173	179	PF00069	0.349
MOD_Plk_4	19	25	PF00069	0.319
MOD_Plk_4	7	13	PF00069	0.313
MOD_ProDKin_1	138	144	PF00069	0.288
TRG_ER_diArg_1	116	118	PF00400	0.317
TRG_ER_diArg_1	170	172	PF00400	0.352
TRG_NES_CRM1_1	257	273	PF08389	0.488

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2E2	Leptomonas seymouri	30%	75%
A0A0N0P2X9	Leptomonas seymouri	32%	88%
A0A0N0P3Z9	Leptomonas seymouri	28%	81%
A0A0N0P407	Leptomonas seymouri	27%	77%
A0A0N0P4P4	Leptomonas seymouri	29%	72%
A0A0N0P7D2	Leptomonas seymouri	35%	92%
A0A0N1HS61	Leptomonas seymouri	32%	95%
A0A0N1I0G1	Leptomonas seymouri	34%	97%
A0A0N1I3G0	Leptomonas seymouri	35%	71%
A0A0N1I8S3	Leptomonas seymouri	33%	79%
A0A0N1I9B7	Leptomonas seymouri	36%	79%
A0A0N1IHY4	Leptomonas seymouri	36%	71%
A0A0N1II59	Leptomonas seymouri	29%	69%
A0A0N1IIU9	Leptomonas seymouri	33%	73%
A0A0N1IL28	Leptomonas seymouri	31%	80%
A0A0N1IM47	Leptomonas seymouri	30%	78%
A0A0N1PC32	Leptomonas seymouri	30%	74%
A0A0N1PCH4	Leptomonas seymouri	34%	87%
A0A0N1PDA9	Leptomonas seymouri	30%	78%
A0A0N1PDG8	Leptomonas seymouri	88%	75%
A0A0S4IJI2	Bodo saltans	30%	96%
A0A0S4IKC2	Bodo saltans	30%	76%
A0A0S4IKY7	Bodo saltans	36%	83%
A0A0S4ILC2	Bodo saltans	30%	68%
A0A0S4IV16	Bodo saltans	32%	75%
A0A0S4IXW3	Bodo saltans	32%	66%
A0A0S4IXX8	Bodo saltans	29%	73%
A0A0S4IYA6	Bodo saltans	32%	93%
A0A0S4J3Y5	Bodo saltans	26%	67%
A0A0S4J8L6	Bodo saltans	29%	77%
A0A0S4JCK3	Bodo saltans	35%	73%
A0A0S4JCQ9	Bodo saltans	56%	76%
A0A0S4JFD4	Bodo saltans	32%	95%
A0A0S4JFM9	Bodo saltans	32%	73%
A0A0S4JIA9	Bodo saltans	33%	96%
A0A0S4JMF5	Bodo saltans	31%	77%
A0A0S4JQ66	Bodo saltans	31%	78%
A0A0S4JTQ2	Bodo saltans	34%	71%
A0A0S4JXW9	Bodo saltans	36%	72%
A0A0S4JZV2	Bodo saltans	35%	86%
A0A0S4KFI2	Bodo saltans	30%	85%
A0A0S4KHR9	Bodo saltans	27%	87%
A0A0S4KHS0	Bodo saltans	31%	73%
A0A1X0NJZ1	Trypanosomatidae	28%	70%
A0A1X0NLN7	Trypanosomatidae	36%	85%
A0A1X0NM44	Trypanosomatidae	29%	83%
A0A1X0NQM7	Trypanosomatidae	31%	71%
A0A1X0NQT9	Trypanosomatidae	31%	82%
A0A1X0NSJ7	Trypanosomatidae	29%	98%
A0A1X0NVV9	Trypanosomatidae	28%	71%
A0A1X0NYE4	Trypanosomatidae	32%	95%
A0A1X0P020	Trypanosomatidae	27%	74%
A0A1X0P1E8	Trypanosomatidae	31%	74%
A0A1X0P246	Trypanosomatidae	29%	66%
A0A1X0P2I7	Trypanosomatidae	36%	68%
A0A1X0P3B9	Trypanosomatidae	35%	75%
A0A1X0P3X8	Trypanosomatidae	34%	88%
A0A1X0P692	Trypanosomatidae	29%	79%
A0A1X0P6E7	Trypanosomatidae	36%	73%
A0A1X0P6U6	Trypanosomatidae	31%	79%
A0A1X0P6Z5	Trypanosomatidae	29%	81%
A0A1X0P798	Trypanosomatidae	31%	82%
A0A1X0P8A0	Trypanosomatidae	35%	92%
A0A1X0P8R6	Trypanosomatidae	67%	77%
A0A1X0P935	Trypanosomatidae	27%	78%
A0A3Q8IAQ1	Leishmania donovani	30%	80%
A0A3Q8IB74	Leishmania donovani	35%	71%
A0A3Q8IH39	Leishmania donovani	33%	71%
A0A3Q8II44	Leishmania donovani	34%	80%
A0A3Q8IIY5	Leishmania donovani	27%	67%
A0A3Q8INS5	Leishmania donovani	33%	97%
A0A3Q8IPR6	Leishmania donovani	34%	88%
A0A3Q8ITZ9	Leishmania donovani	35%	70%
A0A3R7K7W6	Trypanosoma rangeli	36%	69%
A0A3R7KDC2	Trypanosoma rangeli	31%	82%
A0A3R7L9Q6	Trypanosoma rangeli	29%	81%
A0A3R7M0A0	Trypanosoma rangeli	35%	68%
A0A3R7M1U6	Trypanosoma rangeli	25%	77%
A0A3R7MSS9	Trypanosoma rangeli	27%	71%
A0A3R7MWP2	Trypanosoma rangeli	31%	79%
A0A3R7NK21	Trypanosoma rangeli	29%	83%
A0A3S5H528	Leishmania donovani	99%	76%
A0A3S5H725	Leishmania donovani	29%	81%
A0A3S5H7N7	Leishmania donovani	32%	74%
A0A3S5IRK9	Trypanosoma rangeli	27%	89%
A0A3S5IRQ5	Trypanosoma rangeli	31%	68%
A0A3S7WP41	Leishmania donovani	33%	91%
A0A3S7WR45	Leishmania donovani	30%	74%
A0A3S7WRG1	Leishmania donovani	27%	72%
A0A3S7WWL1	Leishmania donovani	32%	95%
A0A3S7X2Z6	Leishmania donovani	30%	70%
A0A3S7X933	Leishmania donovani	29%	77%
A0A3S7XA45	Leishmania donovani	31%	73%
A0A422N0M4	Trypanosoma rangeli	31%	73%
A0A422N9H2	Trypanosoma rangeli	28%	76%
A0A422NCX4	Trypanosoma rangeli	33%	73%
A0A422NDD2	Trypanosoma rangeli	36%	83%
A0A422NQJ6	Trypanosoma rangeli	65%	77%
A0A422NWI9	Trypanosoma rangeli	31%	95%
A0A422P0N6	Trypanosoma rangeli	28%	92%
A0A422P292	Trypanosoma rangeli	33%	92%
A0A422P3I6	Trypanosoma rangeli	33%	67%
A0A451EJH2	Leishmania donovani	25%	75%
A1CAF0	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	36%	76%
A1CL96	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	35%	67%
A1CPG7	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	38%	79%
A1D2C9	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	38%	78%
A1D624	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	35%	67%
A1DES4	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	37%	76%
A1IVT7	Botryotinia fuckeliana (strain B05.10)	37%	81%
A2QN07	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	34%	72%
A2QRF6	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	38%	79%
A2QU77	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	35%	67%
A2XFC8	Oryza sativa subsp. indica	35%	78%
A2Y4B6	Oryza sativa subsp. indica	32%	68%
A3EZ53	Wallemia muriae	35%	100%
A3EZ54	Wallemia sebi	35%	100%
A3EZ55	Wallemia ichthyophaga (strain EXF-994 / CBS 113033)	37%	79%
A3LN91	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	37%	75%
A3LUB9	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	33%	67%
A4H3D2	Leishmania braziliensis	26%	76%
A4H3J3	Leishmania braziliensis	94%	100%
A4H4A1	Leishmania braziliensis	31%	100%
A4H601	Leishmania braziliensis	34%	71%
A4H641	Leishmania braziliensis	29%	74%
A4H9D1	Leishmania braziliensis	29%	81%
A4H9X5	Leishmania braziliensis	36%	71%
A4HA94	Leishmania braziliensis	34%	100%
A4HBW8	Leishmania braziliensis	32%	100%
A4HCE6	Leishmania braziliensis	30%	80%
A4HED7	Leishmania braziliensis	27%	74%
A4HEL2	Leishmania braziliensis	33%	97%
A4HFI2	Leishmania braziliensis	34%	88%
A4HHL5	Leishmania braziliensis	26%	67%
A4HHY4	Leishmania braziliensis	30%	100%
A4HIM5	Leishmania braziliensis	34%	74%
A4HLJ9	Leishmania braziliensis	32%	70%
A4HMJ3	Leishmania braziliensis	29%	77%
A4HNG3	Leishmania braziliensis	31%	73%
A4HNR5	Leishmania braziliensis	36%	100%
A4HQG8	Leishmania braziliensis	34%	100%
A4HRN3	Leishmania infantum	25%	75%
A4HRT2	Leishmania infantum	99%	76%
A4HSH7	Leishmania infantum	33%	91%
A4HUC8	Leishmania infantum	33%	71%
A4HUG1	Leishmania infantum	30%	74%
A4HUS3	Leishmania infantum	27%	72%
A4HXQ3	Leishmania infantum	30%	81%
A4HYH4	Leishmania infantum	36%	79%
A4HZW8	Leishmania infantum	30%	80%
A4I1U3	Leishmania infantum	33%	97%
A4I564	Leishmania infantum	30%	70%
A4I5X0	Leishmania infantum	32%	74%
A4I910	Leishmania infantum	35%	70%
A4IB73	Leishmania infantum	29%	77%
A4IC54	Leishmania infantum	31%	73%
A4ICA4	Leishmania infantum	34%	80%
A4ICT0	Leishmania infantum	35%	92%
A4IIW7	Xenopus tropicalis	31%	68%
A8WIP6	Danio rerio	31%	83%
A8X5H5	Caenorhabditis briggsae	29%	80%
A8XA58	Caenorhabditis briggsae	33%	88%
A9S9Q8	Physcomitrium patens	37%	76%
A9T142	Physcomitrium patens	39%	77%
B0XR80	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	38%	78%
B0Y462	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	37%	76%
B0Y4X4	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	36%	68%
B0Y8W7	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	38%	81%
B2MVY4	Ovis aries	36%	95%
B6DTC0	Bodo saltans	33%	74%
B6DTE5	Bodo saltans	30%	82%
B6DTK9	Bodo saltans	27%	79%
B6F107	Oryza sativa subsp. japonica	29%	86%
C4YGK0	Candida albicans (strain WO-1)	34%	69%
C9ZJ15	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	77%
C9ZLG9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	67%
C9ZLJ4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	77%
C9ZQJ0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	70%
C9ZR94	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	76%
C9ZS83	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	98%
C9ZUD1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	83%
C9ZVD8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	77%
C9ZVG3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	70%
C9ZYF0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	79%
C9ZZI2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	71%
D0A032	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	82%
D0A0D6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	74%
D0A0U8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	79%
D0A1B0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	95%
D0A230	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	60%	77%
D0A2M5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	92%
D0A3L9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	82%
D0A509	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	69%
D0A5Q8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	88%
D0A7P0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	72%
E8NHS0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9ACB1	Leishmania major	26%	75%
E9ACG8	Leishmania major	97%	100%
E9AD33	Leishmania major	35%	88%
E9AE77	Leishmania major	27%	67%
E9AEZ4	Leishmania major	29%	77%
E9AFX4	Leishmania major	30%	73%
E9AGS0	Leishmania infantum	35%	71%
E9AGX6	Leishmania infantum	32%	95%
E9AHC6	Leishmania infantum	36%	88%
E9AJJ9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	75%
E9AKG1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	90%
E9ALK8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	67%
E9AN28	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	71%
E9AN59	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	74%
E9ANF7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	72%
E9ARG4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	81%
E9ARW9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	71%
E9AS98	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	79%
E9ASH4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	92%
E9AV92	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	95%
E9AXY7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	97%
E9AYV7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	88%
E9B0G1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	70%
E9B164	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	74%
E9B3X5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	70%
E9B650	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	77%
E9B727	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	73%
G4N0Z0	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	36%	81%
G4N374	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	36%	69%
G5ECH7	Caenorhabditis elegans	34%	98%
G5EFV5	Caenorhabditis elegans	34%	87%
M1T7M3	Wallemia ichthyophaga (strain EXF-994 / CBS 113033)	36%	78%
O02812	Canis lupus familiaris	34%	80%
O08911	Mus musculus	33%	78%
O13352	Magnaporthe oryzae	36%	69%
O13958	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	78%
O15264	Homo sapiens	31%	79%
O23145	Arabidopsis thaliana	32%	67%
O23236	Arabidopsis thaliana	36%	80%
O42099	Cyprinus carpio	32%	67%
O42376	Danio rerio	34%	79%
O42781	Pneumocystis carinii	38%	82%
O44408	Caenorhabditis elegans	31%	74%
O54833	Mus musculus	28%	82%
O55076	Cricetulus griseus	34%	96%
O59853	Zygosaccharomyces rouxii	36%	68%
O59854	Zygosaccharomyces rouxii	36%	71%
O60145	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	72%
O61443	Drosophila melanogaster	33%	79%
O62618	Drosophila melanogaster	35%	78%
O64816	Arabidopsis thaliana	31%	66%
O74456	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	33%	100%
O76484	Spodoptera frugiperda	28%	81%
O93982	Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229)	36%	67%
O94737	Pneumocystis carinii	37%	78%
O96526	Leishmania major	35%	100%
O96821	Plasmodium knowlesi (strain H)	30%	100%
P00546	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	30%	96%
P04551	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	97%
P06493	Homo sapiens	35%	97%
P08181	Drosophila melanogaster	29%	85%
P0C431	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	34%	80%
P0CP66	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	35%	78%
P0CP67	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	35%	78%
P0CP68	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	36%	79%
P0CP69	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	36%	79%
P11440	Mus musculus	35%	97%
P11802	Homo sapiens	36%	95%
P13863	Gallus gallus	36%	95%
P14681	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	38%	78%
P15790	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	29%	77%
P16892	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	38%	81%
P17157	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	94%
P19784	Homo sapiens	28%	82%
P20427	Bos taurus	28%	82%
P20911	Xenopus laevis	31%	82%
P21708	Rattus norvegicus	32%	76%
P21868	Gallus gallus	28%	73%
P21869	Gallus gallus	28%	82%
P23111	Zea mays	33%	98%
P23437	Xenopus laevis	35%	97%
P23572	Drosophila melanogaster	31%	97%
P23573	Drosophila melanogaster	34%	91%
P24033	Xenopus laevis	35%	95%
P24100	Arabidopsis thaliana	35%	98%
P24923	Medicago sativa	34%	99%
P24941	Homo sapiens	34%	96%
P25859	Arabidopsis thaliana	31%	93%
P26696	Xenopus laevis	32%	80%
P27361	Homo sapiens	32%	76%
P27638	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	38%	77%
P28020	Xenopus laevis	28%	73%
P28482	Homo sapiens	32%	80%
P28523	Zea mays	30%	86%
P28547	Theileria parva	28%	82%
P29618	Oryza sativa subsp. japonica	32%	98%
P29619	Oryza sativa subsp. japonica	32%	98%
P29620	Oryza sativa subsp. japonica	32%	68%
P30285	Mus musculus	35%	95%
P33674	Oryctolagus cuniculus	27%	73%
P34112	Dictyostelium discoideum	32%	97%
P34117	Dictyostelium discoideum	30%	98%
P34556	Caenorhabditis elegans	33%	86%
P35426	Rattus norvegicus	35%	95%
P35567	Xenopus laevis	35%	95%
P36005	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	31%	66%
P38973	Trypanosoma brucei brucei	32%	95%
P39951	Rattus norvegicus	35%	97%
P40417	Drosophila melanogaster	33%	76%
P41808	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	31%	74%
P43063	Candida albicans (strain SC5314 / ATCC MYA-2876)	33%	91%
P43288	Arabidopsis thaliana	33%	71%
P43289	Arabidopsis thaliana	33%	70%
P43450	Carassius auratus	33%	96%
P45983	Homo sapiens	32%	67%
P45984	Homo sapiens	32%	68%
P46196	Bos taurus	32%	80%
P47811	Mus musculus	33%	80%
P47812	Xenopus laevis	32%	80%
P48609	Drosophila melanogaster	37%	98%
P48734	Bos taurus	33%	97%
P48963	Mesocricetus auratus	35%	96%
P49185	Rattus norvegicus	32%	70%
P49186	Rattus norvegicus	32%	68%
P49615	Mus musculus	36%	98%
P49841	Homo sapiens	30%	68%
P50613	Homo sapiens	33%	83%
P50750	Homo sapiens	30%	77%
P51137	Medicago sativa	33%	70%
P51138	Medicago sativa	31%	70%
P51139	Medicago sativa	31%	70%
P51166	Xenopus laevis	35%	98%
P51952	Rattus norvegicus	33%	87%
P51953	Carassius auratus	31%	83%
P51958	Carassius auratus	35%	95%
P52389	Vigna unguiculata	32%	98%
P53778	Homo sapiens	33%	78%
P54119	Ajellomyces capsulatus	34%	89%
P54664	Trypanosoma congolense	32%	95%
P54665	Trypanosoma brucei brucei	36%	83%
P54666	Trypanosoma brucei brucei	36%	92%
P54685	Dictyostelium discoideum	32%	80%
P61075	Plasmodium falciparum (isolate 3D7)	30%	100%
P63085	Mus musculus	32%	80%
P63086	Rattus norvegicus	32%	80%
P68399	Bos taurus	27%	73%
P68400	Homo sapiens	27%	73%
P70618	Rattus norvegicus	33%	80%
P79432	Sus scrofa	36%	95%
P79996	Gallus gallus	32%	75%
P83100	Drosophila melanogaster	33%	81%
P92208	Drosophila melanogaster	31%	77%
P93101	Oxybasis rubra	33%	98%
Q00526	Homo sapiens	33%	94%
Q00532	Homo sapiens	31%	80%
Q00534	Homo sapiens	34%	88%
Q00535	Homo sapiens	35%	98%
Q00646	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	33%	89%
Q00859	Fusarium vanettenii	36%	81%
Q02399	Bos taurus	36%	98%
Q02720	Dictyostelium discoideum	28%	85%
Q03114	Rattus norvegicus	36%	98%
Q03147	Mus musculus	33%	83%
Q04770	Entamoeba histolytica	35%	99%
Q05006	Medicago sativa	32%	98%
Q06060	Pisum sativum	38%	73%
Q06309	Leishmania mexicana	32%	95%
Q07176	Medicago sativa	37%	74%
Q07785	Plasmodium falciparum (isolate K1 / Thailand)	30%	100%
Q09892	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	82%
Q0CIC7	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	33%	78%
Q0D0P5	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	37%	79%
Q0J4I1	Oryza sativa subsp. japonica	32%	88%
Q0U4L8	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	38%	81%
Q10452	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	74%
Q10N20	Oryza sativa subsp. japonica	35%	78%
Q12126	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	31%	86%
Q15131	Homo sapiens	32%	80%
Q15759	Homo sapiens	36%	79%
Q16539	Homo sapiens	33%	80%
Q17446	Caenorhabditis elegans	30%	76%
Q1DUU8	Coccidioides immitis (strain RS)	37%	79%
Q1KTF2	Zymoseptoria tritici (strain CBS 115943 / IPO323)	37%	80%
Q1L5Z8	Torulaspora delbrueckii	36%	67%
Q1RLU9	Danio rerio	31%	69%
Q26671	Theileria annulata	32%	96%
Q27032	Theileria parva	33%	96%
Q2H332	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	37%	80%
Q2PQN9	Glossina morsitans morsitans	35%	98%
Q2TBL8	Bos taurus	33%	80%
Q2U469	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	35%	83%
Q2UC58	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	36%	69%
Q2V419	Arabidopsis thaliana	33%	92%
Q2WFL5	Cochliobolus miyabeanus	37%	81%
Q2WGK3	Trichoderma harzianum	36%	81%
Q32KY4	Bos taurus	36%	95%
Q336X9	Oryza sativa subsp. japonica	37%	76%
Q38772	Antirrhinum majus	34%	98%
Q38773	Antirrhinum majus	34%	100%
Q38775	Antirrhinum majus	32%	92%
Q38HL5	Aspergillus glaucus	38%	78%
Q39010	Arabidopsis thaliana	31%	70%
Q39011	Arabidopsis thaliana	29%	76%
Q39012	Arabidopsis thaliana	31%	71%
Q39019	Arabidopsis thaliana	29%	68%
Q39021	Arabidopsis thaliana	37%	78%
Q39022	Arabidopsis thaliana	36%	76%
Q39023	Arabidopsis thaliana	36%	78%
Q39024	Arabidopsis thaliana	37%	76%
Q39025	Arabidopsis thaliana	36%	76%
Q39026	Arabidopsis thaliana	36%	73%
Q39027	Arabidopsis thaliana	37%	78%
Q3T0N5	Bos taurus	31%	78%
Q3TZA2	Mus musculus	27%	84%
Q3UMM4	Mus musculus	32%	80%
Q3V3A1	Mus musculus	32%	66%
Q40353	Medicago sativa	38%	77%
Q40517	Nicotiana tabacum	39%	77%
Q40518	Nicotiana tabacum	32%	70%
Q40531	Nicotiana tabacum	39%	77%
Q40532	Nicotiana tabacum	38%	73%
Q40884	Petunia hybrida	38%	75%
Q41639	Vigna aconitifolia	34%	98%
Q4KM34	Rattus norvegicus	30%	83%
Q4KM47	Rattus norvegicus	32%	80%
Q4PC06	Ustilago maydis (strain 521 / FGSC 9021)	36%	80%
Q4Q0B0	Leishmania major	34%	100%
Q4Q204	Leishmania major	35%	67%
Q4Q449	Leishmania major	35%	70%
Q4Q701	Leishmania major	33%	74%
Q4Q7S2	Leishmania major	30%	70%
Q4Q9I7	Leishmania major	34%	97%
Q4Q9K2	Leishmania major	28%	74%
Q4QBQ2	Leishmania major	27%	80%
Q4QC88	Leishmania major	32%	100%
Q4QD66	Leishmania major	35%	100%
Q4QDK3	Leishmania major	35%	71%
Q4QE15	Leishmania major	30%	81%
Q4QH69	Leishmania major	27%	72%
Q4QHG6	Leishmania major	30%	74%
Q4QHJ8	Leishmania major	33%	71%
Q4QJE7	Leishmania major	32%	100%
Q4U925	Theileria annulata	28%	82%
Q4W6D3	Cochliobolus heterostrophus	37%	81%
Q4WQR3	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	36%	68%
Q4WSF6	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	38%	78%
Q4WUN7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	37%	76%
Q4WYR6	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	35%	67%
Q4Y4B1	Plasmodium chabaudi	31%	100%
Q4Z6R1	Plasmodium berghei (strain Anka)	31%	100%
Q52PH6	Alternaria brassicicola	37%	81%
Q54QB1	Dictyostelium discoideum	36%	78%
Q54RB2	Dictyostelium discoideum	33%	80%
Q55GS4	Dictyostelium discoideum	34%	78%
Q56R42	Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)	36%	79%
Q5A1D3	Candida albicans (strain SC5314 / ATCC MYA-2876)	34%	68%
Q5BAE1	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	35%	67%
Q5E9Y0	Bos taurus	34%	96%
Q5EAB2	Bos taurus	31%	77%
Q5I6M2	Setosphaeria turcica	37%	87%
Q5J4W4	Oryza sativa subsp. japonica	35%	73%
Q5R7I7	Pongo abelii	29%	83%
Q5RCH1	Pongo abelii	35%	97%
Q5YJC2	Spermophilus citellus	30%	68%
Q5Z7J0	Oryza sativa subsp. japonica	30%	71%
Q5Z859	Oryza sativa subsp. japonica	40%	78%
Q5ZKN1	Gallus gallus	30%	77%
Q60EZ2	Oryza sativa subsp. japonica	33%	71%
Q63538	Rattus norvegicus	33%	78%
Q63699	Rattus norvegicus	35%	96%
Q63844	Mus musculus	32%	76%
Q64261	Mus musculus	31%	88%
Q66HE7	Rattus norvegicus	31%	82%
Q6AXJ9	Danio rerio	32%	82%
Q6BRY2	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	36%	87%
Q6C4M9	Yarrowia lipolytica (strain CLIB 122 / E 150)	36%	74%
Q6C7U8	Yarrowia lipolytica (strain CLIB 122 / E 150)	36%	98%
Q6CCB0	Yarrowia lipolytica (strain CLIB 122 / E 150)	30%	71%
Q6FKD4	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	35%	95%
Q6PWX2	Beauveria bassiana	36%	80%
Q6XKY3	Hypocrea atroviridis	36%	80%
Q6Z437	Oryza sativa subsp. japonica	40%	78%
Q6ZAG3	Oryza sativa subsp. japonica	34%	89%
Q702W0	Blastobotrys adeninivorans	36%	72%
Q751E8	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	34%	95%
Q75Q66	Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422)	34%	80%
Q7RM49	Plasmodium yoelii yoelii	31%	99%
Q7SXE8	Danio rerio	29%	77%
Q80YP0	Mus musculus	33%	94%
Q84SN3	Oryza sativa subsp. japonica	33%	66%
Q84UI5	Oryza sativa subsp. japonica	37%	72%
Q875L0	Cryphonectria parasitica	37%	80%
Q8CEQ0	Mus musculus	33%	82%
Q8GYQ5	Arabidopsis thaliana	36%	77%
Q8IZL9	Homo sapiens	31%	83%
Q8L4P8	Oryza sativa subsp. japonica	32%	95%
Q8LF80	Arabidopsis thaliana	33%	92%
Q8LG64	Arabidopsis thaliana	31%	91%
Q8MXI4	Caenorhabditis elegans	33%	68%
Q8NJT7	Hortaea werneckii	37%	80%
Q8QHK8	Xenopus laevis	32%	67%
Q8SQU8	Encephalitozoon cuniculi (strain GB-M1)	32%	91%
Q8SQW2	Encephalitozoon cuniculi (strain GB-M1)	27%	87%
Q8SR86	Encephalitozoon cuniculi (strain GB-M1)	34%	97%
Q8SRU0	Encephalitozoon cuniculi (strain GB-M1)	32%	90%
Q8SW92	Encephalitozoon cuniculi (strain GB-M1)	30%	93%
Q8TG13	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	30%	85%
Q8TGA9	Blumeria graminis	36%	80%
Q8VZD5	Arabidopsis thaliana	32%	70%
Q8WQ45	Leishmania donovani	35%	92%
Q90327	Cyprinus carpio	30%	67%
Q90336	Cyprinus carpio	34%	80%
Q91727	Xenopus laevis	33%	90%
Q91Y86	Mus musculus	32%	75%
Q92207	Candida albicans (strain SC5314 / ATCC MYA-2876)	37%	76%
Q92241	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	37%	94%
Q92246	Magnaporthe oryzae	36%	81%
Q92398	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	37%	68%
Q95NE7	Pan troglodytes	33%	80%
Q95YH0	Dictyostelium discoideum	30%	76%
Q966Y3	Suberites domuncula	30%	80%
Q96TL5	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	37%	80%
Q9AR27	Oryza sativa subsp. indica	29%	86%
Q9C9M7	Arabidopsis thaliana	30%	82%
Q9C9U2	Arabidopsis thaliana	34%	72%
Q9DG98	Oryzias luzonensis	33%	95%
Q9DGA2	Oryzias javanicus	36%	95%
Q9DGA5	Oryzias curvinotus	34%	95%
Q9DGD3	Oryzias latipes	33%	95%
Q9DGD9	Danio rerio	33%	75%
Q9DGE1	Danio rerio	35%	82%
Q9DGE2	Danio rerio	33%	80%
Q9FVS6	Arabidopsis thaliana	31%	68%
Q9GRU1	Leishmania mexicana	34%	79%
Q9HG11	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	36%	69%
Q9HGY5	Candida albicans	34%	88%
Q9I958	Cyprinus carpio	34%	80%
Q9JHU3	Mus musculus	29%	83%
Q9LMM5	Arabidopsis thaliana	37%	78%
Q9LMT0	Arabidopsis thaliana	30%	73%
Q9LQQ9	Arabidopsis thaliana	37%	79%
Q9LWN0	Oryza sativa subsp. japonica	32%	71%
Q9M1Z5	Arabidopsis thaliana	39%	73%
Q9N272	Pan troglodytes	31%	79%
Q9U2Q9	Caenorhabditis elegans	28%	79%
Q9U6D2	Ancylostoma caninum	33%	76%
Q9U6V4	Leishmania donovani	36%	79%
Q9URT9	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	75%
Q9UV50	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	37%	74%
Q9UV51	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	37%	80%
Q9W739	Rana dybowskii	35%	95%
Q9WTU6	Mus musculus	32%	68%
Q9WTY9	Rattus norvegicus	30%	78%
Q9WUI1	Mus musculus	37%	79%
Q9WV60	Mus musculus	30%	68%
Q9XTR1	Caenorhabditis elegans	31%	71%
Q9XZD6	Plasmodium vivax	30%	100%
Q9Z1B7	Mus musculus	30%	78%
V5AYC9	Trypanosoma cruzi	27%	85%
V5B6E9	Trypanosoma cruzi	27%	81%
V5B8U8	Trypanosoma cruzi	34%	79%
V5BA65	Trypanosoma cruzi	29%	77%
V5BCX5	Trypanosoma cruzi	29%	71%
V5BJT8	Trypanosoma cruzi	35%	87%
V5BLT9	Trypanosoma cruzi	36%	69%
V5BPE2	Trypanosoma cruzi	30%	79%
V5BSG8	Trypanosoma cruzi	32%	73%
V5BTL4	Trypanosoma cruzi	29%	83%
V5BV49	Trypanosoma cruzi	34%	92%
V5BW58	Trypanosoma cruzi	27%	71%
V5BX61	Trypanosoma cruzi	27%	77%
V5CZ20	Trypanosoma cruzi	65%	77%
V5D6X4	Trypanosoma cruzi	31%	95%
V5DA09	Trypanosoma cruzi	31%	71%
V5DDT1	Trypanosoma cruzi	34%	82%
V5DTI8	Trypanosoma cruzi	35%	73%