Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E9AJQ2_LEIMU

TriTrypDb:

LmxM.03.0170

Length:

193

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AJQ2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AJQ2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	70	74	PF00656	0.824
CLV_C14_Caspase3-7	85	89	PF00656	0.531
CLV_PCSK_KEX2_1	161	163	PF00082	0.668
CLV_PCSK_PC1ET2_1	161	163	PF00082	0.668
DOC_ANK_TNKS_1	113	120	PF00023	0.546
DOC_CDC14_PxL_1	178	186	PF14671	0.674
DOC_USP7_MATH_1	76	80	PF00917	0.723
DOC_USP7_MATH_1	84	88	PF00917	0.648
DOC_WW_Pin1_4	141	146	PF00397	0.665
DOC_WW_Pin1_4	77	82	PF00397	0.571
LIG_14-3-3_CanoR_1	51	57	PF00244	0.481
LIG_BIR_II_1	1	5	PF00653	0.808
LIG_CtBP_PxDLS_1	168	172	PF00389	0.748
LIG_FHA_1	47	53	PF00498	0.763
LIG_FHA_1	7	13	PF00498	0.663
LIG_FHA_1	97	103	PF00498	0.485
LIG_FHA_2	183	189	PF00498	0.498
LIG_LIR_Apic_2	2	8	PF02991	0.733
LIG_LIR_Nem_3	48	53	PF02991	0.764
LIG_PCNA_yPIPBox_3	95	109	PF02747	0.531
LIG_RPA_C_Fungi	109	121	PF08784	0.533
LIG_SH2_CRK	53	57	PF00017	0.482
LIG_SH2_SRC	101	104	PF00017	0.642
LIG_SH2_STAP1	103	107	PF00017	0.357
LIG_SH2_STAT5	101	104	PF00017	0.642
LIG_SH3_2	81	86	PF14604	0.527
LIG_SH3_3	1	7	PF00018	0.740
LIG_SH3_3	162	168	PF00018	0.539
LIG_SH3_3	78	84	PF00018	0.538
LIG_SUMO_SIM_anti_2	25	30	PF11976	0.586
LIG_TRAF2_1	138	141	PF00917	0.625
LIG_TRAF2_1	45	48	PF00917	0.759
MOD_CDK_SPxK_1	141	147	PF00069	0.666
MOD_CK1_1	65	71	PF00069	0.701
MOD_CK1_1	87	93	PF00069	0.674
MOD_CK2_1	182	188	PF00069	0.491
MOD_GlcNHglycan	122	125	PF01048	0.634
MOD_GlcNHglycan	155	158	PF01048	0.679
MOD_GSK3_1	153	160	PF00069	0.691
MOD_GSK3_1	58	65	PF00069	0.786
MOD_GSK3_1	6	13	PF00069	0.653
MOD_GSK3_1	84	91	PF00069	0.681
MOD_N-GLC_1	35	40	PF02516	0.709
MOD_PKA_2	120	126	PF00069	0.729
MOD_PKA_2	76	82	PF00069	0.832
MOD_ProDKin_1	141	147	PF00069	0.666
MOD_ProDKin_1	77	83	PF00069	0.569
MOD_SUMO_for_1	138	141	PF00179	0.542
TRG_DiLeu_BaEn_1	170	175	PF01217	0.448
TRG_ENDOCYTIC_2	53	56	PF00928	0.735

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A451EJM2	Leishmania donovani	82%	100%
A4H3I9	Leishmania braziliensis	65%	99%
A4HRS8	Leishmania infantum	81%	100%
E9ACG4	Leishmania major	82%	99%