LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AJP9_LEIMU
TriTrypDb:
LmxM.03.0140
Length:
139

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AJP9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AJP9

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 110 112 PF00675 0.622
CLV_NRD_NRD_1 121 123 PF00675 0.425
CLV_NRD_NRD_1 32 34 PF00675 0.528
CLV_PCSK_FUR_1 108 112 PF00082 0.617
CLV_PCSK_KEX2_1 110 112 PF00082 0.599
CLV_PCSK_KEX2_1 31 33 PF00082 0.527
CLV_PCSK_PC1ET2_1 31 33 PF00082 0.557
CLV_PCSK_SKI1_1 111 115 PF00082 0.537
DEG_APCC_DBOX_1 110 118 PF00400 0.610
DOC_MAPK_gen_1 120 129 PF00069 0.547
DOC_MAPK_MEF2A_6 62 69 PF00069 0.574
DOC_MAPK_NFAT4_5 62 70 PF00069 0.651
DOC_USP7_MATH_1 86 90 PF00917 0.703
DOC_USP7_MATH_1 92 96 PF00917 0.679
LIG_14-3-3_CanoR_1 110 118 PF00244 0.528
LIG_LIR_Gen_1 38 48 PF02991 0.525
LIG_LIR_Nem_3 38 44 PF02991 0.488
LIG_Rb_LxCxE_1 51 68 PF01857 0.442
LIG_SH2_CRK 23 27 PF00017 0.618
LIG_SH2_STAT5 13 16 PF00017 0.571
LIG_SH2_STAT5 43 46 PF00017 0.560
LIG_TRAF2_1 113 116 PF00917 0.613
MOD_CK1_1 6 12 PF00069 0.591
MOD_GlcNHglycan 5 8 PF01048 0.604
MOD_GlcNHglycan 88 91 PF01048 0.665
MOD_GlcNHglycan 93 97 PF01048 0.561
MOD_GSK3_1 76 83 PF00069 0.577
MOD_PKA_2 109 115 PF00069 0.517
MOD_PKA_2 9 15 PF00069 0.561
MOD_Plk_4 9 15 PF00069 0.599
TRG_ENDOCYTIC_2 23 26 PF00928 0.650
TRG_ER_diArg_1 62 65 PF00400 0.549

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IJS5 Leptomonas seymouri 57% 97%
A0A0S4JDM7 Bodo saltans 44% 100%
A0A1X0P8N0 Trypanosomatidae 47% 100%
A0A422N7L0 Trypanosoma rangeli 46% 100%
A0A451EJL9 Leishmania donovani 93% 100%
A4H3I6 Leishmania braziliensis 78% 100%
D0A221 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 43% 100%
E9ACG1 Leishmania major 91% 100%
E9AG33 Leishmania infantum 94% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS