Basal body protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Basal body protein

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AJN2_LEIMU

TriTrypDb:

LmxM.02.0700

Length:

937

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 13
NetGPI	no	yes: 0, no: 13

Cellular components
Term	Name	Level	Count
GO:0005856	cytoskeleton	5	2
GO:0005930	axoneme	2	1
GO:0043226	organelle	2	3
GO:0043228	non-membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043232	intracellular non-membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	3
GO:0005929	cilium	4	1
GO:0031514	motile cilium	5	1
GO:0042995	cell projection	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0120025	plasma membrane bounded cell projection	3	1

Expansion

Sequence features

E9AJN2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AJN2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	115	119	PF00656	0.523
CLV_NRD_NRD_1	107	109	PF00675	0.538
CLV_NRD_NRD_1	197	199	PF00675	0.648
CLV_NRD_NRD_1	226	228	PF00675	0.513
CLV_NRD_NRD_1	279	281	PF00675	0.527
CLV_NRD_NRD_1	345	347	PF00675	0.460
CLV_NRD_NRD_1	366	368	PF00675	0.512
CLV_NRD_NRD_1	380	382	PF00675	0.451
CLV_NRD_NRD_1	611	613	PF00675	0.474
CLV_NRD_NRD_1	646	648	PF00675	0.519
CLV_NRD_NRD_1	880	882	PF00675	0.607
CLV_PCSK_KEX2_1	170	172	PF00082	0.546
CLV_PCSK_KEX2_1	197	199	PF00082	0.648
CLV_PCSK_KEX2_1	226	228	PF00082	0.494
CLV_PCSK_KEX2_1	279	281	PF00082	0.491
CLV_PCSK_KEX2_1	345	347	PF00082	0.460
CLV_PCSK_KEX2_1	366	368	PF00082	0.485
CLV_PCSK_KEX2_1	380	382	PF00082	0.412
CLV_PCSK_KEX2_1	414	416	PF00082	0.621
CLV_PCSK_KEX2_1	455	457	PF00082	0.545
CLV_PCSK_KEX2_1	580	582	PF00082	0.477
CLV_PCSK_KEX2_1	611	613	PF00082	0.493
CLV_PCSK_KEX2_1	615	617	PF00082	0.491
CLV_PCSK_KEX2_1	646	648	PF00082	0.521
CLV_PCSK_KEX2_1	880	882	PF00082	0.610
CLV_PCSK_PC1ET2_1	170	172	PF00082	0.560
CLV_PCSK_PC1ET2_1	414	416	PF00082	0.620
CLV_PCSK_PC1ET2_1	455	457	PF00082	0.577
CLV_PCSK_PC1ET2_1	580	582	PF00082	0.540
CLV_PCSK_PC1ET2_1	615	617	PF00082	0.320
CLV_PCSK_PC7_1	611	617	PF00082	0.394
CLV_PCSK_SKI1_1	263	267	PF00082	0.569
CLV_PCSK_SKI1_1	367	371	PF00082	0.471
CLV_PCSK_SKI1_1	496	500	PF00082	0.487
CLV_PCSK_SKI1_1	583	587	PF00082	0.507
CLV_PCSK_SKI1_1	631	635	PF00082	0.560
CLV_PCSK_SKI1_1	660	664	PF00082	0.480
CLV_PCSK_SKI1_1	725	729	PF00082	0.542
CLV_PCSK_SKI1_1	802	806	PF00082	0.617
DEG_APCC_DBOX_1	860	868	PF00400	0.556
DEG_Nend_UBRbox_1	1	4	PF02207	0.565
DEG_SCF_FBW7_1	39	45	PF00400	0.615
DEG_SPOP_SBC_1	890	894	PF00917	0.476
DOC_CKS1_1	39	44	PF01111	0.668
DOC_MAPK_gen_1	380	387	PF00069	0.558
DOC_MAPK_gen_1	404	412	PF00069	0.355
DOC_MAPK_gen_1	455	461	PF00069	0.387
DOC_MAPK_gen_1	580	589	PF00069	0.516
DOC_MAPK_gen_1	774	783	PF00069	0.563
DOC_MAPK_MEF2A_6	580	589	PF00069	0.603
DOC_MAPK_MEF2A_6	720	728	PF00069	0.477
DOC_PP2B_LxvP_1	930	933	PF13499	0.660
DOC_PP4_FxxP_1	912	915	PF00568	0.625
DOC_USP7_MATH_1	17	21	PF00917	0.567
DOC_USP7_MATH_1	192	196	PF00917	0.596
DOC_USP7_MATH_1	360	364	PF00917	0.537
DOC_USP7_MATH_1	416	420	PF00917	0.396
DOC_USP7_MATH_1	795	799	PF00917	0.600
DOC_USP7_MATH_1	923	927	PF00917	0.683
DOC_WW_Pin1_4	2	7	PF00397	0.749
DOC_WW_Pin1_4	38	43	PF00397	0.649
DOC_WW_Pin1_4	891	896	PF00397	0.748
LIG_14-3-3_CanoR_1	108	117	PF00244	0.555
LIG_14-3-3_CanoR_1	147	155	PF00244	0.628
LIG_14-3-3_CanoR_1	2	6	PF00244	0.451
LIG_14-3-3_CanoR_1	215	220	PF00244	0.603
LIG_14-3-3_CanoR_1	543	553	PF00244	0.500
LIG_14-3-3_CanoR_1	563	567	PF00244	0.247
LIG_14-3-3_CanoR_1	665	673	PF00244	0.518
LIG_14-3-3_CanoR_1	677	683	PF00244	0.464
LIG_14-3-3_CanoR_1	863	871	PF00244	0.473
LIG_Actin_WH2_2	148	165	PF00022	0.602
LIG_APCC_ABBA_1	755	760	PF00400	0.665
LIG_BIR_III_4	621	625	PF00653	0.476
LIG_BRCT_BRCA1_1	58	62	PF00533	0.294
LIG_CaM_IQ_9	772	788	PF13499	0.586
LIG_Clathr_ClatBox_1	73	77	PF01394	0.463
LIG_FHA_1	209	215	PF00498	0.629
LIG_FHA_1	34	40	PF00498	0.428
LIG_FHA_1	730	736	PF00498	0.523
LIG_FHA_1	766	772	PF00498	0.539
LIG_FHA_1	923	929	PF00498	0.732
LIG_FHA_2	129	135	PF00498	0.519
LIG_FHA_2	215	221	PF00498	0.593
LIG_FHA_2	43	49	PF00498	0.557
LIG_FHA_2	465	471	PF00498	0.609
LIG_FHA_2	474	480	PF00498	0.562
LIG_FHA_2	521	527	PF00498	0.548
LIG_FHA_2	59	65	PF00498	0.478
LIG_LIR_Gen_1	51	57	PF02991	0.497
LIG_LIR_Gen_1	547	557	PF02991	0.527
LIG_LIR_Gen_1	66	76	PF02991	0.441
LIG_LIR_Gen_1	767	775	PF02991	0.603
LIG_LIR_Nem_3	317	322	PF02991	0.449
LIG_LIR_Nem_3	51	55	PF02991	0.479
LIG_LIR_Nem_3	547	553	PF02991	0.521
LIG_LIR_Nem_3	59	65	PF02991	0.487
LIG_LIR_Nem_3	66	72	PF02991	0.480
LIG_LIR_Nem_3	747	753	PF02991	0.614
LIG_LIR_Nem_3	767	772	PF02991	0.324
LIG_LIR_Nem_3	88	92	PF02991	0.458
LIG_NRBOX	563	569	PF00104	0.273
LIG_NRBOX	723	729	PF00104	0.589
LIG_OCRL_FandH_1	852	864	PF00620	0.585
LIG_PAM2_1	898	910	PF00658	0.440
LIG_PCNA_yPIPBox_3	288	300	PF02747	0.545
LIG_PCNA_yPIPBox_3	528	540	PF02747	0.470
LIG_REV1ctd_RIR_1	843	851	PF16727	0.570
LIG_SH2_CRK	319	323	PF00017	0.460
LIG_SH2_CRK	550	554	PF00017	0.470
LIG_SH2_CRK	702	706	PF00017	0.563
LIG_SH2_CRK	750	754	PF00017	0.713
LIG_SH2_CRK	769	773	PF00017	0.382
LIG_SH2_NCK_1	348	352	PF00017	0.516
LIG_SH2_SRC	69	72	PF00017	0.588
LIG_SH2_STAP1	348	352	PF00017	0.516
LIG_SH2_STAP1	546	550	PF00017	0.403
LIG_SH2_STAP1	65	69	PF00017	0.507
LIG_SH2_STAT3	65	68	PF00017	0.541
LIG_SH2_STAT3	690	693	PF00017	0.559
LIG_SH2_STAT5	368	371	PF00017	0.561
LIG_SH2_STAT5	481	484	PF00017	0.580
LIG_SH2_STAT5	546	549	PF00017	0.530
LIG_SH3_3	894	900	PF00018	0.755
LIG_SH3_3	910	916	PF00018	0.616
LIG_TRAF2_1	187	190	PF00917	0.662
LIG_TRAF2_1	332	335	PF00917	0.564
LIG_TRAF2_1	468	471	PF00917	0.523
LIG_TRAF2_1	876	879	PF00917	0.439
LIG_TYR_ITIM	700	705	PF00017	0.569
LIG_UBA3_1	504	511	PF00899	0.390
LIG_Vh1_VBS_1	106	124	PF01044	0.514
LIG_WRC_WIRS_1	466	471	PF05994	0.567
LIG_WW_3	914	918	PF00397	0.602
MOD_CDK_SPK_2	891	896	PF00069	0.770
MOD_CK1_1	233	239	PF00069	0.577
MOD_CK1_1	24	30	PF00069	0.722
MOD_CK1_1	464	470	PF00069	0.568
MOD_CK1_1	573	579	PF00069	0.570
MOD_CK1_1	921	927	PF00069	0.696
MOD_CK2_1	261	267	PF00069	0.477
MOD_CK2_1	42	48	PF00069	0.618
MOD_CK2_1	423	429	PF00069	0.713
MOD_CK2_1	464	470	PF00069	0.528
MOD_CK2_1	473	479	PF00069	0.511
MOD_CK2_1	503	509	PF00069	0.506
MOD_CK2_1	518	524	PF00069	0.415
MOD_CK2_1	58	64	PF00069	0.502
MOD_DYRK1A_RPxSP_1	2	6	PF00069	0.451
MOD_DYRK1A_RPxSP_1	896	900	PF00069	0.639
MOD_GlcNHglycan	19	22	PF01048	0.731
MOD_GlcNHglycan	23	26	PF01048	0.735
MOD_GlcNHglycan	235	238	PF01048	0.561
MOD_GlcNHglycan	418	421	PF01048	0.503
MOD_GlcNHglycan	762	765	PF01048	0.669
MOD_GlcNHglycan	925	928	PF01048	0.645
MOD_GSK3_1	108	115	PF00069	0.489
MOD_GSK3_1	142	149	PF00069	0.587
MOD_GSK3_1	17	24	PF00069	0.738
MOD_GSK3_1	283	290	PF00069	0.511
MOD_GSK3_1	29	36	PF00069	0.623
MOD_GSK3_1	38	45	PF00069	0.597
MOD_GSK3_1	416	423	PF00069	0.644
MOD_GSK3_1	461	468	PF00069	0.585
MOD_GSK3_1	570	577	PF00069	0.504
MOD_GSK3_1	660	667	PF00069	0.533
MOD_GSK3_1	885	892	PF00069	0.743
MOD_GSK3_1	896	903	PF00069	0.636
MOD_GSK3_1	915	922	PF00069	0.574
MOD_GSK3_1	92	99	PF00069	0.469
MOD_N-GLC_1	30	35	PF02516	0.681
MOD_N-GLC_1	729	734	PF02516	0.564
MOD_NEK2_1	1	6	PF00069	0.735
MOD_NEK2_1	162	167	PF00069	0.568
MOD_NEK2_1	199	204	PF00069	0.579
MOD_NEK2_1	214	219	PF00069	0.482
MOD_NEK2_1	221	226	PF00069	0.510
MOD_NEK2_1	231	236	PF00069	0.419
MOD_NEK2_1	535	540	PF00069	0.490
MOD_NEK2_1	574	579	PF00069	0.551
MOD_NEK2_1	845	850	PF00069	0.478
MOD_NEK2_1	867	872	PF00069	0.602
MOD_NEK2_1	919	924	PF00069	0.555
MOD_NEK2_1	92	97	PF00069	0.459
MOD_NEK2_2	192	197	PF00069	0.676
MOD_NEK2_2	360	365	PF00069	0.464
MOD_PIKK_1	208	214	PF00454	0.605
MOD_PIKK_1	221	227	PF00454	0.530
MOD_PIKK_1	283	289	PF00454	0.518
MOD_PIKK_1	481	487	PF00454	0.560
MOD_PIKK_1	675	681	PF00454	0.514
MOD_PIKK_1	845	851	PF00454	0.589
MOD_PKA_1	108	114	PF00069	0.510
MOD_PKA_2	1	7	PF00069	0.565
MOD_PKA_2	134	140	PF00069	0.637
MOD_PKA_2	146	152	PF00069	0.532
MOD_PKA_2	214	220	PF00069	0.580
MOD_PKA_2	273	279	PF00069	0.497
MOD_PKA_2	542	548	PF00069	0.492
MOD_PKA_2	562	568	PF00069	0.248
MOD_PKA_2	574	580	PF00069	0.353
MOD_PKA_2	610	616	PF00069	0.482
MOD_PKA_2	664	670	PF00069	0.560
MOD_PKA_2	862	868	PF00069	0.416
MOD_PKA_2	879	885	PF00069	0.657
MOD_Plk_1	128	134	PF00069	0.540
MOD_Plk_2-3	112	118	PF00069	0.591
MOD_Plk_2-3	261	267	PF00069	0.425
MOD_Plk_2-3	58	64	PF00069	0.540
MOD_Plk_4	461	467	PF00069	0.636
MOD_Plk_4	535	541	PF00069	0.494
MOD_Plk_4	562	568	PF00069	0.371
MOD_Plk_4	678	684	PF00069	0.468
MOD_Plk_4	92	98	PF00069	0.469
MOD_ProDKin_1	2	8	PF00069	0.751
MOD_ProDKin_1	38	44	PF00069	0.639
MOD_ProDKin_1	891	897	PF00069	0.742
MOD_SUMO_for_1	141	144	PF00179	0.574
MOD_SUMO_for_1	169	172	PF00179	0.584
MOD_SUMO_for_1	585	588	PF00179	0.527
MOD_SUMO_rev_2	255	265	PF00179	0.387
MOD_SUMO_rev_2	506	513	PF00179	0.518
MOD_SUMO_rev_2	582	587	PF00179	0.374
TRG_DiLeu_BaEn_1	723	728	PF01217	0.533
TRG_DiLeu_BaEn_1	767	772	PF01217	0.627
TRG_DiLeu_BaEn_4	429	435	PF01217	0.532
TRG_DiLeu_BaEn_4	625	631	PF01217	0.274
TRG_DiLeu_BaLyEn_6	102	107	PF01217	0.459
TRG_ENDOCYTIC_2	319	322	PF00928	0.444
TRG_ENDOCYTIC_2	550	553	PF00928	0.454
TRG_ENDOCYTIC_2	69	72	PF00928	0.576
TRG_ENDOCYTIC_2	702	705	PF00928	0.567
TRG_ENDOCYTIC_2	750	753	PF00928	0.686
TRG_ENDOCYTIC_2	758	761	PF00928	0.695
TRG_ENDOCYTIC_2	769	772	PF00928	0.543
TRG_ENDOCYTIC_2	89	92	PF00928	0.446
TRG_ENDOCYTIC_2	909	912	PF00928	0.629
TRG_ER_diArg_1	196	198	PF00400	0.667
TRG_ER_diArg_1	226	228	PF00400	0.514
TRG_ER_diArg_1	279	281	PF00400	0.561
TRG_ER_diArg_1	345	347	PF00400	0.460
TRG_ER_diArg_1	366	368	PF00400	0.601
TRG_ER_diArg_1	880	883	PF00400	0.602
TRG_NLS_MonoExtN_4	612	619	PF00514	0.394
TRG_Pf-PMV_PEXEL_1	197	201	PF00026	0.655
TRG_Pf-PMV_PEXEL_1	733	738	PF00026	0.462
TRG_Pf-PMV_PEXEL_1	780	784	PF00026	0.523

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZ56	Leptomonas seymouri	65%	100%
A0A0N1I2V1	Leptomonas seymouri	25%	91%
A0A0S4JMK5	Bodo saltans	26%	100%
A0A0S4KGN1	Bodo saltans	33%	98%
A0A1X0NJT4	Trypanosomatidae	38%	100%
A0A381MLP4	Leishmania infantum	91%	100%
A0A3Q8IAS8	Leishmania donovani	91%	100%
A0A422NB26	Trypanosoma rangeli	36%	100%
A0A451EJK4	Leishmania donovani	91%	100%
A4H3K2	Leishmania braziliensis	25%	99%
A4HG33	Leishmania braziliensis	76%	100%
A8HUA1	Chlamydomonas reinhardtii	27%	100%
B2RW38	Mus musculus	27%	100%
C9ZJ55	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	91%
E9ACE4	Leishmania major	92%	100%
E9ACX3	Leishmania major	92%	100%
Q5T655	Homo sapiens	27%	100%
V5D614	Trypanosoma cruzi	38%	100%