LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania mexicana
UniProt:
E9AJL7_LEIMU
TriTrypDb:
LmxM.02.0550
Length:
163

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 4
Forrest at al. (procyclic) no yes: 8
Silverman et al. no yes: 0
Pissara et al. yes yes: 30
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 24
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 20
NetGPI no yes: 0, no: 20
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AJL7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AJL7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 25 29 PF00656 0.554
CLV_PCSK_SKI1_1 52 56 PF00082 0.551
DOC_CYCLIN_RxL_1 46 57 PF00134 0.691
DOC_MAPK_gen_1 104 113 PF00069 0.437
DOC_MAPK_gen_1 151 160 PF00069 0.590
DOC_MAPK_MEF2A_6 123 130 PF00069 0.450
DOC_MAPK_NFAT4_5 123 131 PF00069 0.467
DOC_PP4_FxxP_1 10 13 PF00568 0.434
DOC_USP7_MATH_1 13 17 PF00917 0.366
DOC_USP7_MATH_1 90 94 PF00917 0.648
DOC_WW_Pin1_4 86 91 PF00397 0.702
LIG_14-3-3_CanoR_1 142 148 PF00244 0.541
LIG_Actin_WH2_2 127 144 PF00022 0.434
LIG_Clathr_ClatBox_1 128 132 PF01394 0.462
LIG_FHA_1 142 148 PF00498 0.525
LIG_FHA_1 153 159 PF00498 0.506
LIG_FHA_1 37 43 PF00498 0.601
LIG_LIR_Apic_2 7 13 PF02991 0.430
LIG_SH2_STAT3 117 120 PF00017 0.466
LIG_SH2_STAT5 117 120 PF00017 0.455
LIG_SH3_2 47 52 PF14604 0.553
LIG_SH3_3 44 50 PF00018 0.573
LIG_SUMO_SIM_par_1 127 132 PF11976 0.546
LIG_TRAF2_1 133 136 PF00917 0.549
MOD_CK1_1 41 47 PF00069 0.595
MOD_GlcNHglycan 56 59 PF01048 0.663
MOD_GlcNHglycan 73 76 PF01048 0.794
MOD_GSK3_1 37 44 PF00069 0.518
MOD_GSK3_1 86 93 PF00069 0.820
MOD_N-GLC_1 91 96 PF02516 0.633
MOD_NEK2_1 141 146 PF00069 0.503
MOD_NEK2_1 53 58 PF00069 0.561
MOD_PIKK_1 153 159 PF00454 0.607
MOD_PIKK_1 41 47 PF00454 0.685
MOD_PKA_2 141 147 PF00069 0.504
MOD_Plk_1 153 159 PF00069 0.524
MOD_Plk_4 143 149 PF00069 0.631
MOD_ProDKin_1 86 92 PF00069 0.703
MOD_SUMO_rev_2 101 108 PF00179 0.511
TRG_DiLeu_BaEn_2 48 54 PF01217 0.542
TRG_DiLeu_BaEn_4 136 142 PF01217 0.564
TRG_NES_CRM1_1 119 135 PF08389 0.547
TRG_Pf-PMV_PEXEL_1 32 37 PF00026 0.618

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P2D0 Leptomonas seymouri 67% 100%
A0A0N1HW96 Leptomonas seymouri 28% 100%
A0A0S4IPF2 Bodo saltans 29% 100%
A0A0S4JFI1 Bodo saltans 32% 100%
A0A1X0NKC2 Trypanosomatidae 34% 100%
A0A1X0P259 Trypanosomatidae 31% 100%
A0A3R7K0R9 Trypanosoma rangeli 28% 100%
A0A3S5H506 Leishmania donovani 93% 100%
A0A3S7X3W3 Leishmania donovani 30% 100%
A0A422NFX4 Trypanosoma rangeli 36% 100%
A4H3E5 Leishmania braziliensis 78% 99%
A4HIL9 Leishmania braziliensis 30% 70%
A4HRQ0 Leishmania infantum 93% 100%
A4I5W4 Leishmania infantum 30% 100%
C9ZR85 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
E9ACC9 Leishmania major 91% 100%
E9B159 Leishmania mexicana (strain MHOM/GT/2001/U1103) 31% 100%
Q4Q707 Leishmania major 30% 70%
V5BMX8 Trypanosoma cruzi 29% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS