DUF3340 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AJL3_LEIMU

TriTrypDb:

LmxM.02.0510

Length:

170

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AJL3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AJL3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	58	60	PF00675	0.605
CLV_PCSK_KEX2_1	58	60	PF00082	0.605
CLV_PCSK_SKI1_1	109	113	PF00082	0.578
CLV_PCSK_SKI1_1	15	19	PF00082	0.465
CLV_PCSK_SKI1_1	58	62	PF00082	0.471
CLV_PCSK_SKI1_1	7	11	PF00082	0.456
DEG_Nend_Nbox_1	1	3	PF02207	0.589
DOC_CYCLIN_yCln2_LP_2	112	118	PF00134	0.602
DOC_USP7_MATH_1	28	32	PF00917	0.508
DOC_USP7_MATH_1	85	89	PF00917	0.606
DOC_WW_Pin1_4	120	125	PF00397	0.418
DOC_WW_Pin1_4	69	74	PF00397	0.639
LIG_Actin_WH2_2	44	60	PF00022	0.652
LIG_BIR_III_4	117	121	PF00653	0.617
LIG_DCNL_PONY_1	1	4	PF03556	0.452
LIG_deltaCOP1_diTrp_1	107	111	PF00928	0.567
LIG_FHA_1	12	18	PF00498	0.541
LIG_FHA_1	28	34	PF00498	0.463
LIG_FHA_1	62	68	PF00498	0.532
LIG_FHA_1	76	82	PF00498	0.549
LIG_FHA_2	143	149	PF00498	0.570
LIG_FHA_2	161	167	PF00498	0.612
LIG_FHA_2	91	97	PF00498	0.610
LIG_LIR_Nem_3	107	111	PF02991	0.681
LIG_PTAP_UEV_1	76	81	PF05743	0.425
LIG_SH2_STAT3	161	164	PF00017	0.588
LIG_SH3_3	16	22	PF00018	0.613
LIG_SH3_3	74	80	PF00018	0.432
LIG_TRAF2_1	93	96	PF00917	0.611
LIG_TRAF2_1	99	102	PF00917	0.544
MOD_CDK_SPK_2	122	127	PF00069	0.423
MOD_CDK_SPxxK_3	120	127	PF00069	0.425
MOD_CK2_1	142	148	PF00069	0.619
MOD_CK2_1	23	29	PF00069	0.640
MOD_CK2_1	90	96	PF00069	0.618
MOD_GSK3_1	128	135	PF00069	0.420
MOD_GSK3_1	23	30	PF00069	0.602
MOD_GSK3_1	43	50	PF00069	0.617
MOD_GSK3_1	59	66	PF00069	0.496
MOD_GSK3_1	69	76	PF00069	0.545
MOD_GSK3_1	7	14	PF00069	0.502
MOD_NEK2_1	2	7	PF00069	0.537
MOD_NEK2_1	47	52	PF00069	0.632
MOD_PIKK_1	160	166	PF00454	0.611
MOD_PKA_2	90	96	PF00069	0.557
MOD_Plk_1	28	34	PF00069	0.467
MOD_Plk_4	28	34	PF00069	0.484
MOD_ProDKin_1	120	126	PF00069	0.421
MOD_ProDKin_1	69	75	PF00069	0.638
MOD_SUMO_rev_2	94	99	PF00179	0.423
TRG_DiLeu_BaEn_2	106	112	PF01217	0.572
TRG_ER_diArg_1	57	59	PF00400	0.609
TRG_Pf-PMV_PEXEL_1	137	141	PF00026	0.596
TRG_Pf-PMV_PEXEL_1	151	155	PF00026	0.416
TRG_Pf-PMV_PEXEL_1	45	49	PF00026	0.654

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A451EJI7	Leishmania donovani	81%	100%
A4H3E2	Leishmania braziliensis	67%	100%
A4HRP6	Leishmania infantum	81%	100%
E9ACC5	Leishmania major	78%	100%