LeishMANIAdb
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Secreted protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Secreted protein
Gene product:
hypothetical protein
Species:
Leishmania mexicana
UniProt:
E9AJK3_LEIMU
TriTrypDb:
LmxM.02.0400
Length:
59

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Cellular components
Term Name Level Count
GO:0016020 membrane 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

E9AJK3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AJK3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_MEL_PAP_1 30 36 PF00089 0.558
CLV_NRD_NRD_1 32 34 PF00675 0.562
CLV_PCSK_KEX2_1 32 34 PF00082 0.562
CLV_PCSK_SKI1_1 4 8 PF00082 0.422
CLV_PCSK_SKI1_1 49 53 PF00082 0.324
DEG_APCC_DBOX_1 3 11 PF00400 0.538
DOC_CYCLIN_RxL_1 46 56 PF00134 0.394
DOC_CYCLIN_yCln2_LP_2 19 25 PF00134 0.394
DOC_MAPK_gen_1 32 38 PF00069 0.429
DOC_MAPK_MEF2A_6 4 13 PF00069 0.455
DOC_MAPK_NFAT4_5 4 12 PF00069 0.455
DOC_MAPK_RevD_3 17 33 PF00069 0.420
DOC_SPAK_OSR1_1 33 37 PF12202 0.356
DOC_USP7_MATH_1 25 29 PF00917 0.359
DOC_WW_Pin1_4 18 23 PF00397 0.394
DOC_WW_Pin1_4 53 58 PF00397 0.421
LIG_BIR_II_1 1 5 PF00653 0.546
LIG_BRCT_BRCA1_1 40 44 PF00533 0.394
LIG_EH1_1 7 15 PF00400 0.277
LIG_FHA_1 25 31 PF00498 0.455
LIG_LIR_Nem_3 41 47 PF02991 0.394
LIG_NRBOX 15 21 PF00104 0.361
LIG_NRBOX 47 53 PF00104 0.510
LIG_NRBOX 8 14 PF00104 0.359
LIG_SH3_3 19 25 PF00018 0.275
LIG_Sin3_3 3 10 PF02671 0.455
LIG_SUMO_SIM_par_1 15 21 PF11976 0.394
MOD_CDC14_SPxK_1 56 59 PF00782 0.576
MOD_CDK_SPxK_1 53 59 PF00069 0.432
MOD_GlcNHglycan 1 4 PF01048 0.470
MOD_GlcNHglycan 40 43 PF01048 0.395
MOD_NEK2_1 38 43 PF00069 0.417
MOD_PK_1 32 38 PF00069 0.357
MOD_PKA_1 32 38 PF00069 0.357
MOD_PKA_2 32 38 PF00069 0.403
MOD_Plk_4 25 31 PF00069 0.435
MOD_ProDKin_1 18 24 PF00069 0.394
MOD_ProDKin_1 53 59 PF00069 0.432
TRG_ER_diArg_1 31 33 PF00400 0.364

Homologs

Protein Taxonomy Sequence identity Coverage
A0A451EJH6 Leishmania donovani 71% 100%
A4HRN7 Leishmania infantum 71% 100%
E9ACB5 Leishmania major 74% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS