Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E9AJG5_LEIMU

TriTrypDb:

LmxM.01.0790

Length:

513

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AJG5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AJG5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	78	82	PF00656	0.663
CLV_NRD_NRD_1	111	113	PF00675	0.739
CLV_NRD_NRD_1	193	195	PF00675	0.722
CLV_NRD_NRD_1	329	331	PF00675	0.746
CLV_NRD_NRD_1	369	371	PF00675	0.726
CLV_NRD_NRD_1	460	462	PF00675	0.702
CLV_NRD_NRD_1	87	89	PF00675	0.558
CLV_PCSK_KEX2_1	111	113	PF00082	0.744
CLV_PCSK_KEX2_1	193	195	PF00082	0.722
CLV_PCSK_KEX2_1	324	326	PF00082	0.710
CLV_PCSK_KEX2_1	328	330	PF00082	0.751
CLV_PCSK_KEX2_1	369	371	PF00082	0.726
CLV_PCSK_KEX2_1	460	462	PF00082	0.702
CLV_PCSK_KEX2_1	467	469	PF00082	0.520
CLV_PCSK_KEX2_1	87	89	PF00082	0.558
CLV_PCSK_PC1ET2_1	324	326	PF00082	0.542
CLV_PCSK_PC1ET2_1	467	469	PF00082	0.603
CLV_PCSK_PC7_1	325	331	PF00082	0.540
CLV_PCSK_SKI1_1	139	143	PF00082	0.590
CLV_PCSK_SKI1_1	495	499	PF00082	0.651
DEG_Nend_Nbox_1	1	3	PF02207	0.658
DEG_SCF_FBW7_1	180	187	PF00400	0.624
DEG_SPOP_SBC_1	406	410	PF00917	0.747
DOC_CKS1_1	309	314	PF01111	0.541
DOC_CKS1_1	45	50	PF01111	0.537
DOC_CKS1_1	77	82	PF01111	0.547
DOC_MAPK_gen_1	260	269	PF00069	0.617
DOC_MAPK_gen_1	369	376	PF00069	0.721
DOC_MAPK_gen_1	467	474	PF00069	0.597
DOC_PP1_RVXF_1	471	477	PF00149	0.596
DOC_USP7_MATH_1	125	129	PF00917	0.693
DOC_USP7_MATH_1	148	152	PF00917	0.581
DOC_USP7_MATH_1	184	188	PF00917	0.736
DOC_USP7_MATH_1	237	241	PF00917	0.692
DOC_USP7_MATH_1	304	308	PF00917	0.666
DOC_USP7_MATH_1	353	357	PF00917	0.768
DOC_USP7_MATH_1	406	410	PF00917	0.747
DOC_USP7_MATH_1	423	427	PF00917	0.648
DOC_USP7_MATH_1	477	481	PF00917	0.629
DOC_USP7_MATH_1	64	68	PF00917	0.704
DOC_USP7_MATH_1	95	99	PF00917	0.741
DOC_WW_Pin1_4	117	122	PF00397	0.747
DOC_WW_Pin1_4	180	185	PF00397	0.785
DOC_WW_Pin1_4	216	221	PF00397	0.775
DOC_WW_Pin1_4	284	289	PF00397	0.782
DOC_WW_Pin1_4	30	35	PF00397	0.545
DOC_WW_Pin1_4	308	313	PF00397	0.583
DOC_WW_Pin1_4	389	394	PF00397	0.729
DOC_WW_Pin1_4	44	49	PF00397	0.519
DOC_WW_Pin1_4	59	64	PF00397	0.545
DOC_WW_Pin1_4	72	77	PF00397	0.568
DOC_WW_Pin1_4	88	93	PF00397	0.665
LIG_14-3-3_CanoR_1	111	121	PF00244	0.776
LIG_14-3-3_CanoR_1	407	417	PF00244	0.843
LIG_14-3-3_CanoR_1	438	445	PF00244	0.700
LIG_14-3-3_CanoR_1	446	452	PF00244	0.593
LIG_14-3-3_CanoR_1	495	500	PF00244	0.651
LIG_14-3-3_CanoR_1	87	92	PF00244	0.697
LIG_14-3-3_CanoR_1	9	17	PF00244	0.545
LIG_BIR_III_4	377	381	PF00653	0.690
LIG_BRCT_BRCA1_1	54	58	PF00533	0.553
LIG_FHA_1	23	29	PF00498	0.614
LIG_FHA_1	304	310	PF00498	0.538
LIG_FHA_1	394	400	PF00498	0.693
LIG_FHA_1	413	419	PF00498	0.844
LIG_FHA_1	492	498	PF00498	0.652
LIG_FHA_2	198	204	PF00498	0.694
LIG_LIR_Apic_2	144	150	PF02991	0.602
LIG_LIR_Apic_2	450	454	PF02991	0.661
LIG_LIR_Gen_1	151	160	PF02991	0.533
LIG_LIR_Nem_3	151	155	PF02991	0.618
LIG_LIR_Nem_3	156	162	PF02991	0.512
LIG_LIR_Nem_3	381	387	PF02991	0.708
LIG_SH2_CRK	4	8	PF00017	0.483
LIG_SH2_CRK	434	438	PF00017	0.653
LIG_SH2_PTP2	256	259	PF00017	0.577
LIG_SH2_SRC	451	454	PF00017	0.662
LIG_SH2_STAT5	256	259	PF00017	0.549
LIG_SH2_STAT5	451	454	PF00017	0.641
LIG_SH3_1	282	288	PF00018	0.701
LIG_SH3_3	219	225	PF00018	0.741
LIG_SH3_3	282	288	PF00018	0.785
LIG_SH3_3	306	312	PF00018	0.541
LIG_SH3_3	42	48	PF00018	0.708
LIG_SH3_3	74	80	PF00018	0.546
LIG_TRAF2_1	200	203	PF00917	0.694
MOD_CDK_SPxxK_3	30	37	PF00069	0.547
MOD_CDK_SPxxK_3	308	315	PF00069	0.544
MOD_CK1_1	117	123	PF00069	0.745
MOD_CK1_1	128	134	PF00069	0.486
MOD_CK1_1	18	24	PF00069	0.634
MOD_CK1_1	238	244	PF00069	0.494
MOD_CK1_1	409	415	PF00069	0.752
MOD_CK1_1	426	432	PF00069	0.666
MOD_CK1_1	441	447	PF00069	0.566
MOD_CK1_1	480	486	PF00069	0.649
MOD_CK1_1	52	58	PF00069	0.736
MOD_CK1_1	59	65	PF00069	0.547
MOD_CK1_1	8	14	PF00069	0.690
MOD_CK1_1	97	103	PF00069	0.704
MOD_CK2_1	197	203	PF00069	0.697
MOD_CK2_1	72	78	PF00069	0.551
MOD_Cter_Amidation	322	325	PF01082	0.554
MOD_GlcNHglycan	123	126	PF01048	0.746
MOD_GlcNHglycan	186	189	PF01048	0.760
MOD_GlcNHglycan	239	243	PF01048	0.654
MOD_GlcNHglycan	272	275	PF01048	0.767
MOD_GlcNHglycan	292	295	PF01048	0.774
MOD_GlcNHglycan	331	334	PF01048	0.788
MOD_GlcNHglycan	346	349	PF01048	0.652
MOD_GlcNHglycan	355	358	PF01048	0.721
MOD_GlcNHglycan	41	44	PF01048	0.685
MOD_GlcNHglycan	52	55	PF01048	0.638
MOD_GlcNHglycan	83	86	PF01048	0.761
MOD_GlcNHglycan	99	102	PF01048	0.603
MOD_GSK3_1	111	118	PF00069	0.755
MOD_GSK3_1	121	128	PF00069	0.626
MOD_GSK3_1	15	22	PF00069	0.724
MOD_GSK3_1	180	187	PF00069	0.762
MOD_GSK3_1	304	311	PF00069	0.594
MOD_GSK3_1	344	351	PF00069	0.547
MOD_GSK3_1	35	42	PF00069	0.757
MOD_GSK3_1	389	396	PF00069	0.729
MOD_GSK3_1	405	412	PF00069	0.617
MOD_GSK3_1	422	429	PF00069	0.654
MOD_GSK3_1	46	53	PF00069	0.627
MOD_GSK3_1	491	498	PF00069	0.650
MOD_GSK3_1	59	66	PF00069	0.750
MOD_GSK3_1	72	79	PF00069	0.602
MOD_GSK3_1	83	90	PF00069	0.625
MOD_N-GLC_1	50	55	PF02516	0.611
MOD_N-GLC_2	440	442	PF02516	0.522
MOD_NEK2_1	413	418	PF00069	0.538
MOD_NEK2_1	58	63	PF00069	0.666
MOD_NEK2_2	292	297	PF00069	0.633
MOD_OFUCOSY	436	442	PF10250	0.703
MOD_PIKK_1	105	111	PF00454	0.546
MOD_PIKK_1	304	310	PF00454	0.692
MOD_PIKK_1	480	486	PF00454	0.649
MOD_PKA_1	111	117	PF00069	0.630
MOD_PKA_1	329	335	PF00069	0.746
MOD_PKA_1	87	93	PF00069	0.543
MOD_PKA_2	111	117	PF00069	0.739
MOD_PKA_2	125	131	PF00069	0.606
MOD_PKA_2	329	335	PF00069	0.746
MOD_PKA_2	406	412	PF00069	0.749
MOD_PKA_2	8	14	PF00069	0.603
MOD_PKA_2	86	92	PF00069	0.639
MOD_PKB_1	37	45	PF00069	0.639
MOD_PKB_1	493	501	PF00069	0.653
MOD_Plk_1	197	203	PF00069	0.697
MOD_Plk_4	395	401	PF00069	0.700
MOD_Plk_4	413	419	PF00069	0.690
MOD_Plk_4	447	453	PF00069	0.673
MOD_Plk_4	477	483	PF00069	0.630
MOD_ProDKin_1	117	123	PF00069	0.745
MOD_ProDKin_1	180	186	PF00069	0.783
MOD_ProDKin_1	216	222	PF00069	0.777
MOD_ProDKin_1	284	290	PF00069	0.783
MOD_ProDKin_1	30	36	PF00069	0.545
MOD_ProDKin_1	308	314	PF00069	0.583
MOD_ProDKin_1	389	395	PF00069	0.730
MOD_ProDKin_1	44	50	PF00069	0.519
MOD_ProDKin_1	59	65	PF00069	0.547
MOD_ProDKin_1	72	78	PF00069	0.571
MOD_ProDKin_1	88	94	PF00069	0.665
TRG_DiLeu_BaEn_1	239	244	PF01217	0.644
TRG_DiLeu_BaEn_1	470	475	PF01217	0.590
TRG_DiLeu_LyEn_5	470	475	PF01217	0.590
TRG_ENDOCYTIC_2	256	259	PF00928	0.656
TRG_ER_diArg_1	193	195	PF00400	0.722
TRG_ER_diArg_1	28	31	PF00400	0.554
TRG_ER_diArg_1	328	330	PF00400	0.757
TRG_ER_diArg_1	459	461	PF00400	0.667
TRG_ER_diArg_1	492	495	PF00400	0.659
TRG_NES_CRM1_1	153	168	PF08389	0.467
TRG_Pf-PMV_PEXEL_1	105	109	PF00026	0.695

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A451EJD3	Leishmania donovani	80%	97%
A4H394	Leishmania braziliensis	58%	98%
A4HRK2	Leishmania infantum	79%	97%
E9AC70	Leishmania major	81%	99%