Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AJG3_LEIMU

TriTrypDb:

LmxM.01.0760

Length:

324

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AJG3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AJG3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	223	227	PF00656	0.531
CLV_NRD_NRD_1	18	20	PF00675	0.582
CLV_PCSK_KEX2_1	17	19	PF00082	0.599
CLV_PCSK_PC7_1	14	20	PF00082	0.607
CLV_PCSK_SKI1_1	295	299	PF00082	0.502
DEG_SCF_FBW7_1	177	183	PF00400	0.390
DOC_CKS1_1	163	168	PF01111	0.524
DOC_CKS1_1	177	182	PF01111	0.361
DOC_MAPK_gen_1	51	60	PF00069	0.442
DOC_MAPK_MEF2A_6	244	253	PF00069	0.556
DOC_MAPK_MEF2A_6	96	103	PF00069	0.412
DOC_PP4_FxxP_1	236	239	PF00568	0.553
DOC_USP7_MATH_1	13	17	PF00917	0.620
DOC_USP7_MATH_1	145	149	PF00917	0.470
DOC_USP7_MATH_1	156	160	PF00917	0.499
DOC_USP7_MATH_1	180	184	PF00917	0.481
DOC_USP7_MATH_1	193	197	PF00917	0.655
DOC_USP7_MATH_1	204	208	PF00917	0.512
DOC_USP7_MATH_1	225	229	PF00917	0.663
DOC_USP7_MATH_1	91	95	PF00917	0.537
DOC_WW_Pin1_4	128	133	PF00397	0.412
DOC_WW_Pin1_4	162	167	PF00397	0.637
DOC_WW_Pin1_4	176	181	PF00397	0.365
DOC_WW_Pin1_4	191	196	PF00397	0.585
DOC_WW_Pin1_4	89	94	PF00397	0.634
LIG_14-3-3_CanoR_1	279	288	PF00244	0.585
LIG_APCC_ABBA_1	63	68	PF00400	0.395
LIG_BIR_II_1	1	5	PF00653	0.554
LIG_FHA_1	119	125	PF00498	0.482
LIG_FHA_1	131	137	PF00498	0.470
LIG_FHA_2	296	302	PF00498	0.480
LIG_LIR_Apic_2	233	239	PF02991	0.558
LIG_LIR_Gen_1	111	120	PF02991	0.450
LIG_LIR_Gen_1	174	181	PF02991	0.516
LIG_LIR_Gen_1	61	70	PF02991	0.406
LIG_LIR_Nem_3	111	115	PF02991	0.443
LIG_LIR_Nem_3	174	178	PF02991	0.502
LIG_LIR_Nem_3	179	184	PF02991	0.681
LIG_LIR_Nem_3	61	66	PF02991	0.401
LIG_LIR_Nem_3	67	72	PF02991	0.358
LIG_SH2_CRK	112	116	PF00017	0.449
LIG_SH2_CRK	175	179	PF00017	0.494
LIG_SH2_CRK	181	185	PF00017	0.539
LIG_SH2_CRK	25	29	PF00017	0.441
LIG_SH2_NCK_1	175	179	PF00017	0.494
LIG_SH2_NCK_1	181	185	PF00017	0.489
LIG_SH2_STAT3	23	26	PF00017	0.440
LIG_SH2_STAT3	307	310	PF00017	0.480
LIG_SH2_STAT5	280	283	PF00017	0.561
LIG_SH2_STAT5	307	310	PF00017	0.480
LIG_SH3_3	160	166	PF00018	0.603
LIG_SH3_3	174	180	PF00018	0.357
LIG_SH3_3	192	198	PF00018	0.623
LIG_SH3_3	317	323	PF00018	0.507
LIG_SH3_3	40	46	PF00018	0.416
LIG_SH3_3	87	93	PF00018	0.641
LIG_SH3_5	171	175	PF00018	0.392
LIG_SH3_CIN85_PxpxPR_1	164	169	PF14604	0.538
LIG_TRAF2_1	290	293	PF00917	0.534
LIG_TYR_ITSM	177	184	PF00017	0.521
MOD_CDK_SPxxK_3	128	135	PF00069	0.394
MOD_CDK_SPxxK_3	162	169	PF00069	0.571
MOD_CDK_SPxxK_3	89	96	PF00069	0.544
MOD_CK1_1	182	188	PF00069	0.555
MOD_CK1_1	191	197	PF00069	0.630
MOD_CK1_1	92	98	PF00069	0.462
MOD_CK2_1	242	248	PF00069	0.701
MOD_CK2_1	287	293	PF00069	0.573
MOD_CK2_1	295	301	PF00069	0.507
MOD_GlcNHglycan	1	4	PF01048	0.752
MOD_GlcNHglycan	215	218	PF01048	0.660
MOD_GlcNHglycan	226	230	PF01048	0.624
MOD_GlcNHglycan	233	236	PF01048	0.498
MOD_GlcNHglycan	28	31	PF01048	0.446
MOD_GSK3_1	120	127	PF00069	0.476
MOD_GSK3_1	145	152	PF00069	0.448
MOD_GSK3_1	176	183	PF00069	0.520
MOD_GSK3_1	187	194	PF00069	0.499
MOD_NEK2_1	124	129	PF00069	0.504
MOD_NEK2_1	151	156	PF00069	0.486
MOD_NEK2_1	231	236	PF00069	0.568
MOD_NEK2_1	270	275	PF00069	0.521
MOD_NEK2_2	156	161	PF00069	0.522
MOD_PKA_2	13	19	PF00069	0.575
MOD_PKA_2	219	225	PF00069	0.557
MOD_PKA_2	254	260	PF00069	0.661
MOD_Plk_1	149	155	PF00069	0.344
MOD_Plk_4	204	210	PF00069	0.487
MOD_ProDKin_1	128	134	PF00069	0.398
MOD_ProDKin_1	162	168	PF00069	0.631
MOD_ProDKin_1	176	182	PF00069	0.366
MOD_ProDKin_1	191	197	PF00069	0.586
MOD_ProDKin_1	89	95	PF00069	0.629
MOD_SUMO_rev_2	258	263	PF00179	0.551
TRG_ENDOCYTIC_2	112	115	PF00928	0.444
TRG_ENDOCYTIC_2	175	178	PF00928	0.495
TRG_ENDOCYTIC_2	181	184	PF00928	0.688
TRG_ENDOCYTIC_2	25	28	PF00928	0.440
TRG_ER_diArg_1	17	19	PF00400	0.599
TRG_ER_diArg_1	49	52	PF00400	0.406
TRG_Pf-PMV_PEXEL_1	279	283	PF00026	0.565

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A451EJC9	Leishmania donovani	79%	66%
E9AC67	Leishmania major	79%	100%