Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AJF4_LEIMU

TriTrypDb:

LmxM.01.0670

Length:

288

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AJF4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AJF4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	5	9	PF00656	0.475
CLV_PCSK_SKI1_1	16	20	PF00082	0.571
DEG_SPOP_SBC_1	234	238	PF00917	0.517
DOC_CKS1_1	138	143	PF01111	0.658
DOC_MAPK_gen_1	122	132	PF00069	0.627
DOC_PP1_RVXF_1	14	20	PF00149	0.552
DOC_PP4_FxxP_1	19	22	PF00568	0.527
DOC_USP7_MATH_1	121	125	PF00917	0.597
DOC_USP7_MATH_1	185	189	PF00917	0.622
DOC_USP7_MATH_1	234	238	PF00917	0.517
DOC_USP7_MATH_1	37	41	PF00917	0.721
DOC_WW_Pin1_4	137	142	PF00397	0.692
DOC_WW_Pin1_4	157	162	PF00397	0.628
DOC_WW_Pin1_4	198	203	PF00397	0.636
DOC_WW_Pin1_4	210	215	PF00397	0.680
DOC_WW_Pin1_4	222	227	PF00397	0.575
DOC_WW_Pin1_4	261	266	PF00397	0.651
DOC_WW_Pin1_4	63	68	PF00397	0.632
LIG_14-3-3_CanoR_1	125	130	PF00244	0.720
LIG_14-3-3_CanoR_1	279	288	PF00244	0.604
LIG_14-3-3_CanoR_1	50	55	PF00244	0.582
LIG_14-3-3_CanoR_1	81	89	PF00244	0.636
LIG_14-3-3_CanoR_1	91	101	PF00244	0.480
LIG_BRCT_BRCA1_1	281	285	PF00533	0.598
LIG_FHA_1	64	70	PF00498	0.516
LIG_FHA_2	175	181	PF00498	0.581
LIG_FHA_2	22	28	PF00498	0.661
LIG_LIR_Gen_1	171	181	PF02991	0.590
LIG_LIR_Gen_1	282	288	PF02991	0.593
LIG_LIR_Gen_1	45	54	PF02991	0.607
LIG_LIR_Gen_1	8	18	PF02991	0.454
LIG_LIR_LC3C_4	12	15	PF02991	0.445
LIG_LIR_Nem_3	171	176	PF02991	0.604
LIG_LIR_Nem_3	206	212	PF02991	0.583
LIG_LIR_Nem_3	282	288	PF02991	0.593
LIG_LIR_Nem_3	45	51	PF02991	0.606
LIG_LIR_Nem_3	8	13	PF02991	0.449
LIG_PDZ_Class_3	283	288	PF00595	0.660
LIG_SH2_CRK	193	197	PF00017	0.641
LIG_SH3_3	120	126	PF00018	0.494
LIG_Sin3_3	114	121	PF02671	0.493
LIG_SUMO_SIM_par_1	127	134	PF11976	0.637
LIG_TRAF2_1	177	180	PF00917	0.586
LIG_WRC_WIRS_1	170	175	PF05994	0.557
MOD_CDK_SPK_2	137	142	PF00069	0.662
MOD_CK1_1	124	130	PF00069	0.595
MOD_CK1_1	131	137	PF00069	0.605
MOD_CK1_1	155	161	PF00069	0.754
MOD_CK1_1	221	227	PF00069	0.700
MOD_CK1_1	235	241	PF00069	0.809
MOD_CK1_1	277	283	PF00069	0.620
MOD_CK1_1	40	46	PF00069	0.596
MOD_CK1_1	90	96	PF00069	0.584
MOD_CK2_1	174	180	PF00069	0.657
MOD_CK2_1	21	27	PF00069	0.606
MOD_CK2_1	278	284	PF00069	0.697
MOD_CK2_1	28	34	PF00069	0.657
MOD_GlcNHglycan	142	145	PF01048	0.685
MOD_GlcNHglycan	154	157	PF01048	0.760
MOD_GlcNHglycan	187	190	PF01048	0.608
MOD_GlcNHglycan	205	208	PF01048	0.776
MOD_GlcNHglycan	269	272	PF01048	0.635
MOD_GlcNHglycan	42	45	PF01048	0.594
MOD_GlcNHglycan	77	80	PF01048	0.618
MOD_GlcNHglycan	94	97	PF01048	0.607
MOD_GSK3_1	121	128	PF00069	0.629
MOD_GSK3_1	136	143	PF00069	0.596
MOD_GSK3_1	157	164	PF00069	0.707
MOD_GSK3_1	165	172	PF00069	0.677
MOD_GSK3_1	218	225	PF00069	0.650
MOD_GSK3_1	232	239	PF00069	0.705
MOD_GSK3_1	263	270	PF00069	0.634
MOD_GSK3_1	274	281	PF00069	0.614
MOD_GSK3_1	42	49	PF00069	0.587
MOD_GSK3_1	71	78	PF00069	0.701
MOD_GSK3_1	79	86	PF00069	0.689
MOD_GSK3_1	87	94	PF00069	0.480
MOD_N-GLC_1	136	141	PF02516	0.662
MOD_N-GLC_1	267	272	PF02516	0.665
MOD_N-GLC_1	40	45	PF02516	0.661
MOD_NEK2_1	152	157	PF00069	0.625
MOD_NEK2_1	253	258	PF00069	0.693
MOD_NEK2_1	80	85	PF00069	0.642
MOD_NEK2_2	255	260	PF00069	0.522
MOD_PIKK_1	155	161	PF00454	0.695
MOD_PIKK_1	263	269	PF00454	0.671
MOD_PIKK_1	274	280	PF00454	0.618
MOD_PIKK_1	42	48	PF00454	0.579
MOD_PK_1	125	131	PF00069	0.627
MOD_PKA_2	121	127	PF00069	0.675
MOD_PKA_2	274	280	PF00069	0.616
MOD_PKA_2	80	86	PF00069	0.671
MOD_PKA_2	90	96	PF00069	0.504
MOD_Plk_4	125	131	PF00069	0.600
MOD_Plk_4	169	175	PF00069	0.629
MOD_ProDKin_1	137	143	PF00069	0.692
MOD_ProDKin_1	157	163	PF00069	0.629
MOD_ProDKin_1	198	204	PF00069	0.639
MOD_ProDKin_1	210	216	PF00069	0.679
MOD_ProDKin_1	222	228	PF00069	0.574
MOD_ProDKin_1	261	267	PF00069	0.652
MOD_ProDKin_1	63	69	PF00069	0.635
TRG_ENDOCYTIC_2	193	196	PF00928	0.642

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I318	Leptomonas seymouri	43%	89%
A0A3S5H4W5	Leishmania donovani	85%	96%
A4H385	Leishmania braziliensis	65%	93%
A4HRJ0	Leishmania infantum	84%	95%
E9AC58	Leishmania major	81%	100%