Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Beat-regulation protein

Species:

Leishmania mexicana

UniProt:

E9AJE9_LEIMU

TriTrypDb:

LmxM.01.0620

Length:

566

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AJE9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AJE9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	2	6	PF00656	0.450
CLV_C14_Caspase3-7	229	233	PF00656	0.392
CLV_C14_Caspase3-7	294	298	PF00656	0.498
CLV_NRD_NRD_1	306	308	PF00675	0.725
CLV_NRD_NRD_1	341	343	PF00675	0.608
CLV_NRD_NRD_1	432	434	PF00675	0.622
CLV_NRD_NRD_1	548	550	PF00675	0.580
CLV_PCSK_FUR_1	538	542	PF00082	0.499
CLV_PCSK_KEX2_1	305	307	PF00082	0.740
CLV_PCSK_KEX2_1	340	342	PF00082	0.611
CLV_PCSK_KEX2_1	432	434	PF00082	0.622
CLV_PCSK_KEX2_1	471	473	PF00082	0.672
CLV_PCSK_KEX2_1	540	542	PF00082	0.502
CLV_PCSK_KEX2_1	546	548	PF00082	0.510
CLV_PCSK_PC1ET2_1	471	473	PF00082	0.672
CLV_PCSK_PC1ET2_1	540	542	PF00082	0.502
CLV_PCSK_PC1ET2_1	546	548	PF00082	0.510
CLV_PCSK_PC7_1	536	542	PF00082	0.496
CLV_PCSK_SKI1_1	112	116	PF00082	0.370
CLV_PCSK_SKI1_1	342	346	PF00082	0.515
CLV_PCSK_SKI1_1	374	378	PF00082	0.503
DEG_APCC_DBOX_1	111	119	PF00400	0.377
DEG_APCC_DBOX_1	136	144	PF00400	0.370
DEG_APCC_DBOX_1	317	325	PF00400	0.530
DEG_APCC_DBOX_1	535	543	PF00400	0.584
DEG_SCF_FBW7_1	325	332	PF00400	0.685
DEG_SCF_FBW7_1	376	381	PF00400	0.506
DEG_SCF_FBW7_1	402	408	PF00400	0.587
DEG_SCF_FBW7_2	405	412	PF00400	0.393
DOC_CDC14_PxL_1	76	84	PF14671	0.438
DOC_CKS1_1	402	407	PF01111	0.592
DOC_CYCLIN_RxL_1	142	153	PF00134	0.243
DOC_MAPK_gen_1	132	140	PF00069	0.394
DOC_MAPK_MEF2A_6	235	243	PF00069	0.392
DOC_MAPK_MEF2A_6	520	529	PF00069	0.521
DOC_PP2B_LxvP_1	403	406	PF13499	0.546
DOC_PP4_FxxP_1	510	513	PF00568	0.590
DOC_USP7_MATH_1	168	172	PF00917	0.575
DOC_USP7_MATH_1	398	402	PF00917	0.634
DOC_USP7_MATH_1	461	465	PF00917	0.595
DOC_USP7_MATH_1	476	480	PF00917	0.639
DOC_USP7_MATH_1	513	517	PF00917	0.624
DOC_USP7_UBL2_3	546	550	PF12436	0.556
DOC_WW_Pin1_4	325	330	PF00397	0.760
DOC_WW_Pin1_4	350	355	PF00397	0.634
DOC_WW_Pin1_4	358	363	PF00397	0.623
DOC_WW_Pin1_4	374	379	PF00397	0.503
DOC_WW_Pin1_4	401	406	PF00397	0.606
DOC_WW_Pin1_4	447	452	PF00397	0.485
DOC_WW_Pin1_4	49	54	PF00397	0.647
DOC_WW_Pin1_4	520	525	PF00397	0.598
LIG_14-3-3_CanoR_1	305	314	PF00244	0.726
LIG_14-3-3_CanoR_1	320	325	PF00244	0.516
LIG_14-3-3_CanoR_1	330	335	PF00244	0.604
LIG_14-3-3_CanoR_1	340	345	PF00244	0.525
LIG_14-3-3_CanoR_1	486	494	PF00244	0.540
LIG_14-3-3_CanoR_1	530	539	PF00244	0.504
LIG_14-3-3_CanoR_1	89	98	PF00244	0.398
LIG_APCC_ABBA_1	421	426	PF00400	0.416
LIG_BRCT_BRCA1_1	24	28	PF00533	0.587
LIG_BRCT_BRCA1_1	271	275	PF00533	0.431
LIG_DLG_GKlike_1	330	338	PF00625	0.591
LIG_FHA_1	142	148	PF00498	0.446
LIG_FHA_1	238	244	PF00498	0.411
LIG_FHA_1	247	253	PF00498	0.402
LIG_FHA_1	326	332	PF00498	0.613
LIG_FHA_1	59	65	PF00498	0.453
LIG_FHA_2	227	233	PF00498	0.393
LIG_FHA_2	271	277	PF00498	0.643
LIG_FHA_2	311	317	PF00498	0.492
LIG_FHA_2	409	415	PF00498	0.561
LIG_GSK3_LRP6_1	405	411	PF00069	0.476
LIG_LIR_Apic_2	420	425	PF02991	0.447
LIG_LIR_Apic_2	509	513	PF02991	0.593
LIG_LIR_Apic_2	516	522	PF02991	0.554
LIG_LIR_Gen_1	144	154	PF02991	0.457
LIG_LIR_Gen_1	262	268	PF02991	0.386
LIG_LIR_Gen_1	92	98	PF02991	0.397
LIG_LIR_Nem_3	144	149	PF02991	0.448
LIG_LIR_Nem_3	262	266	PF02991	0.367
LIG_LIR_Nem_3	426	431	PF02991	0.441
LIG_LIR_Nem_3	92	97	PF02991	0.404
LIG_NRBOX	320	326	PF00104	0.583
LIG_Pex14_2	263	267	PF04695	0.373
LIG_SH2_CRK	428	432	PF00017	0.464
LIG_SH2_CRK	519	523	PF00017	0.517
LIG_SH2_STAT3	380	383	PF00017	0.514
LIG_SH2_STAT5	146	149	PF00017	0.349
LIG_SH2_STAT5	260	263	PF00017	0.381
LIG_SH2_STAT5	422	425	PF00017	0.447
LIG_SH3_3	183	189	PF00018	0.545
LIG_SH3_3	403	409	PF00018	0.548
LIG_SH3_3	515	521	PF00018	0.563
LIG_SUMO_SIM_par_1	139	144	PF11976	0.453
LIG_SUMO_SIM_par_1	239	245	PF11976	0.409
LIG_SUMO_SIM_par_1	411	420	PF11976	0.528
LIG_TRAF2_1	411	414	PF00917	0.567
LIG_UBA3_1	71	78	PF00899	0.489
LIG_WW_3	511	515	PF00397	0.476
MOD_CDK_SPK_2	325	330	PF00069	0.685
MOD_CK1_1	19	25	PF00069	0.518
MOD_CK1_1	270	276	PF00069	0.609
MOD_CK1_1	309	315	PF00069	0.614
MOD_CK1_1	352	358	PF00069	0.630
MOD_CK1_1	401	407	PF00069	0.715
MOD_CK1_1	464	470	PF00069	0.578
MOD_CK1_1	474	480	PF00069	0.664
MOD_CK1_1	58	64	PF00069	0.449
MOD_CK1_1	92	98	PF00069	0.487
MOD_CK2_1	120	126	PF00069	0.388
MOD_CK2_1	270	276	PF00069	0.629
MOD_CK2_1	408	414	PF00069	0.484
MOD_DYRK1A_RPxSP_1	520	524	PF00069	0.520
MOD_GlcNHglycan	10	13	PF01048	0.564
MOD_GlcNHglycan	170	173	PF01048	0.655
MOD_GlcNHglycan	174	177	PF01048	0.611
MOD_GlcNHglycan	219	224	PF01048	0.412
MOD_GlcNHglycan	254	257	PF01048	0.396
MOD_GlcNHglycan	294	297	PF01048	0.529
MOD_GlcNHglycan	334	337	PF01048	0.524
MOD_GlcNHglycan	464	467	PF01048	0.603
MOD_GlcNHglycan	476	479	PF01048	0.782
MOD_GlcNHglycan	480	483	PF01048	0.631
MOD_GlcNHglycan	497	500	PF01048	0.658
MOD_GlcNHglycan	94	97	PF01048	0.485
MOD_GSK3_1	168	175	PF00069	0.611
MOD_GSK3_1	18	25	PF00069	0.540
MOD_GSK3_1	242	249	PF00069	0.485
MOD_GSK3_1	267	274	PF00069	0.502
MOD_GSK3_1	305	312	PF00069	0.730
MOD_GSK3_1	320	327	PF00069	0.511
MOD_GSK3_1	358	365	PF00069	0.591
MOD_GSK3_1	368	375	PF00069	0.503
MOD_GSK3_1	401	408	PF00069	0.504
MOD_GSK3_1	474	481	PF00069	0.723
MOD_GSK3_1	49	56	PF00069	0.631
MOD_GSK3_1	525	532	PF00069	0.516
MOD_GSK3_1	85	92	PF00069	0.424
MOD_LATS_1	469	475	PF00433	0.522
MOD_N-GLC_1	495	500	PF02516	0.664
MOD_N-GLC_1	530	535	PF02516	0.512
MOD_N-GLC_2	42	44	PF02516	0.499
MOD_NEK2_1	184	189	PF00069	0.577
MOD_NEK2_1	190	195	PF00069	0.576
MOD_NEK2_1	226	231	PF00069	0.468
MOD_NEK2_1	268	273	PF00069	0.379
MOD_NEK2_1	314	319	PF00069	0.686
MOD_NEK2_1	324	329	PF00069	0.571
MOD_NEK2_1	368	373	PF00069	0.541
MOD_NEK2_1	462	467	PF00069	0.516
MOD_NEK2_1	494	499	PF00069	0.671
MOD_NEK2_1	525	530	PF00069	0.545
MOD_PIKK_1	342	348	PF00454	0.693
MOD_PIKK_1	486	492	PF00454	0.541
MOD_PIKK_1	558	564	PF00454	0.640
MOD_PKA_1	305	311	PF00069	0.720
MOD_PKA_1	340	346	PF00069	0.614
MOD_PKA_1	471	477	PF00069	0.673
MOD_PKA_2	292	298	PF00069	0.654
MOD_PKA_2	305	311	PF00069	0.573
MOD_PKA_2	329	335	PF00069	0.599
MOD_PKA_2	340	346	PF00069	0.616
MOD_PKA_2	471	477	PF00069	0.673
MOD_PKA_2	513	519	PF00069	0.611
MOD_PKA_2	529	535	PF00069	0.508
MOD_PKB_1	318	326	PF00069	0.489
MOD_PKB_1	340	348	PF00069	0.591
MOD_PKB_1	484	492	PF00069	0.567
MOD_Plk_1	205	211	PF00069	0.418
MOD_Plk_1	530	536	PF00069	0.487
MOD_Plk_1	85	91	PF00069	0.491
MOD_Plk_4	242	248	PF00069	0.481
MOD_Plk_4	320	326	PF00069	0.589
MOD_Plk_4	398	404	PF00069	0.626
MOD_ProDKin_1	325	331	PF00069	0.760
MOD_ProDKin_1	350	356	PF00069	0.634
MOD_ProDKin_1	358	364	PF00069	0.622
MOD_ProDKin_1	374	380	PF00069	0.507
MOD_ProDKin_1	401	407	PF00069	0.598
MOD_ProDKin_1	447	453	PF00069	0.488
MOD_ProDKin_1	49	55	PF00069	0.647
MOD_ProDKin_1	520	526	PF00069	0.597
TRG_DiLeu_BaEn_1	413	418	PF01217	0.438
TRG_ENDOCYTIC_2	146	149	PF00928	0.349
TRG_ENDOCYTIC_2	260	263	PF00928	0.381
TRG_ENDOCYTIC_2	428	431	PF00928	0.518
TRG_ER_diArg_1	304	307	PF00400	0.753
TRG_ER_diArg_1	318	321	PF00400	0.524
TRG_ER_diArg_1	339	342	PF00400	0.658
TRG_ER_diArg_1	431	433	PF00400	0.564
TRG_ER_diArg_1	535	538	PF00400	0.490
TRG_NES_CRM1_1	103	117	PF08389	0.378
TRG_Pf-PMV_PEXEL_1	540	544	PF00026	0.499

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P577	Leptomonas seymouri	44%	89%
A0A451EJB6	Leishmania donovani	76%	95%
A4H333	Leishmania braziliensis	61%	100%
A4HRI5	Leishmania infantum	76%	96%
E9AC53	Leishmania major	75%	100%