Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AJA9_LEIMU

TriTrypDb:

LmxM.01.0230

Length:

138

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9AJA9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AJA9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	69	73	PF00082	0.563
CLV_Separin_Metazoa	77	81	PF03568	0.705
DEG_MDM2_SWIB_1	51	58	PF02201	0.611
DEG_Nend_Nbox_1	1	3	PF02207	0.686
DOC_MAPK_MEF2A_6	3	10	PF00069	0.609
DOC_PP4_FxxP_1	62	65	PF00568	0.719
LIG_14-3-3_CanoR_1	120	128	PF00244	0.681
LIG_14-3-3_CanoR_1	129	137	PF00244	0.654
LIG_14-3-3_CanoR_1	69	78	PF00244	0.480
LIG_BRCT_BRCA1_1	47	51	PF00533	0.692
LIG_FHA_1	20	26	PF00498	0.606
LIG_FHA_1	70	76	PF00498	0.520
LIG_FHA_2	68	74	PF00498	0.643
LIG_LIR_Apic_2	19	24	PF02991	0.596
LIG_LIR_Apic_2	61	65	PF02991	0.724
LIG_LIR_Gen_1	91	100	PF02991	0.435
LIG_LIR_Nem_3	22	26	PF02991	0.577
LIG_LIR_Nem_3	48	54	PF02991	0.601
LIG_LIR_Nem_3	91	95	PF02991	0.459
LIG_LYPXL_yS_3	23	26	PF13949	0.600
LIG_Pex14_2	51	55	PF04695	0.729
LIG_SH2_CRK	121	125	PF00017	0.619
LIG_SH2_CRK	21	25	PF00017	0.595
LIG_SH2_STAT5	110	113	PF00017	0.609
LIG_SH2_STAT5	21	24	PF00017	0.595
LIG_TYR_ITIM	119	124	PF00017	0.436
LIG_WRC_WIRS_1	89	94	PF05994	0.454
MOD_CK1_1	105	111	PF00069	0.675
MOD_CK1_1	45	51	PF00069	0.601
MOD_GlcNHglycan	104	107	PF01048	0.559
MOD_GlcNHglycan	47	50	PF01048	0.573
MOD_GlcNHglycan	51	54	PF01048	0.554
MOD_GlcNHglycan	86	89	PF01048	0.570
MOD_GlcNHglycan	95	98	PF01048	0.691
MOD_GSK3_1	28	35	PF00069	0.681
MOD_GSK3_1	37	44	PF00069	0.624
MOD_GSK3_1	45	52	PF00069	0.603
MOD_GSK3_1	54	61	PF00069	0.666
MOD_GSK3_1	84	91	PF00069	0.578
MOD_N-GLC_1	129	134	PF02516	0.749
MOD_NEK2_1	1	6	PF00069	0.583
MOD_NEK2_1	102	107	PF00069	0.386
MOD_NEK2_1	16	21	PF00069	0.605
MOD_NEK2_1	54	59	PF00069	0.738
MOD_NEK2_1	78	83	PF00069	0.604
MOD_NEK2_1	90	95	PF00069	0.618
MOD_PIKK_1	119	125	PF00454	0.437
MOD_PIKK_1	16	22	PF00454	0.605
MOD_PKA_2	119	125	PF00069	0.717
MOD_PKB_1	127	135	PF00069	0.653
MOD_Plk_1	67	73	PF00069	0.650
MOD_Plk_4	105	111	PF00069	0.593
TRG_ENDOCYTIC_2	121	124	PF00928	0.617
TRG_ENDOCYTIC_2	23	26	PF00928	0.548
TRG_ENDOCYTIC_2	27	30	PF00928	0.563
TRG_Pf-PMV_PEXEL_1	69	73	PF00026	0.567

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6P0	Leptomonas seymouri	51%	100%
A0A3S5H4T9	Leishmania donovani	92%	100%
A4H348	Leishmania braziliensis	79%	100%
E9AC12	Leishmania major	87%	100%