Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AJ98_LEIMU

TriTrypDb:

LmxM.01.0120

Length:

402

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AJ98

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AJ98

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	368	372	PF00656	0.623
CLV_NRD_NRD_1	102	104	PF00675	0.745
CLV_PCSK_KEX2_1	102	104	PF00082	0.745
CLV_PCSK_KEX2_1	390	392	PF00082	0.814
CLV_PCSK_KEX2_1	64	66	PF00082	0.685
CLV_PCSK_PC1ET2_1	390	392	PF00082	0.814
CLV_PCSK_PC1ET2_1	64	66	PF00082	0.685
CLV_PCSK_PC7_1	98	104	PF00082	0.618
CLV_PCSK_SKI1_1	110	114	PF00082	0.634
CLV_PCSK_SKI1_1	390	394	PF00082	0.578
DEG_Nend_UBRbox_1	1	4	PF02207	0.576
DEG_SPOP_SBC_1	163	167	PF00917	0.641
DEG_SPOP_SBC_1	220	224	PF00917	0.833
DEG_SPOP_SBC_1	93	97	PF00917	0.600
DOC_CKS1_1	58	63	PF01111	0.687
DOC_MAPK_gen_1	17	25	PF00069	0.794
DOC_PP2B_LxvP_1	214	217	PF13499	0.616
DOC_SPAK_OSR1_1	391	395	PF12202	0.812
DOC_USP7_MATH_1	115	119	PF00917	0.858
DOC_USP7_MATH_1	183	187	PF00917	0.762
DOC_USP7_MATH_1	188	192	PF00917	0.809
DOC_USP7_MATH_1	204	208	PF00917	0.559
DOC_USP7_MATH_1	220	224	PF00917	0.553
DOC_USP7_MATH_1	277	281	PF00917	0.812
DOC_USP7_MATH_1	346	350	PF00917	0.641
DOC_USP7_MATH_1	36	40	PF00917	0.719
DOC_USP7_MATH_1	365	369	PF00917	0.531
DOC_USP7_MATH_1	375	379	PF00917	0.697
DOC_USP7_MATH_1	93	97	PF00917	0.600
DOC_WW_Pin1_4	111	116	PF00397	0.858
DOC_WW_Pin1_4	141	146	PF00397	0.631
DOC_WW_Pin1_4	153	158	PF00397	0.687
DOC_WW_Pin1_4	196	201	PF00397	0.579
DOC_WW_Pin1_4	209	214	PF00397	0.630
DOC_WW_Pin1_4	265	270	PF00397	0.845
DOC_WW_Pin1_4	27	32	PF00397	0.766
DOC_WW_Pin1_4	291	296	PF00397	0.860
DOC_WW_Pin1_4	316	321	PF00397	0.781
DOC_WW_Pin1_4	326	331	PF00397	0.767
DOC_WW_Pin1_4	57	62	PF00397	0.691
LIG_14-3-3_CanoR_1	336	341	PF00244	0.627
LIG_BRCT_BRCA1_1	185	189	PF00533	0.827
LIG_BRCT_BRCA1_1	224	228	PF00533	0.577
LIG_FHA_1	306	312	PF00498	0.627
LIG_FHA_2	238	244	PF00498	0.608
LIG_FHA_2	58	64	PF00498	0.608
LIG_FHA_2	74	80	PF00498	0.700
LIG_LIR_Apic_2	83	89	PF02991	0.803
LIG_LIR_Nem_3	387	392	PF02991	0.587
LIG_LIR_Nem_3	63	69	PF02991	0.692
LIG_MYND_1	213	217	PF01753	0.613
LIG_PDZ_Class_1	397	402	PF00595	0.580
LIG_SH2_CRK	229	233	PF00017	0.828
LIG_SH2_CRK	86	90	PF00017	0.806
LIG_SH2_NCK_1	86	90	PF00017	0.806
LIG_SH2_SRC	84	87	PF00017	0.817
LIG_SH2_STAP1	229	233	PF00017	0.828
LIG_SH2_STAT5	58	61	PF00017	0.604
LIG_SH2_STAT5	66	69	PF00017	0.531
LIG_SH3_1	293	299	PF00018	0.622
LIG_SH3_1	328	334	PF00018	0.611
LIG_SH3_2	145	150	PF14604	0.632
LIG_SH3_2	197	202	PF14604	0.588
LIG_SH3_2	331	336	PF14604	0.606
LIG_SH3_3	109	115	PF00018	0.625
LIG_SH3_3	142	148	PF00018	0.765
LIG_SH3_3	154	160	PF00018	0.752
LIG_SH3_3	194	200	PF00018	0.582
LIG_SH3_3	214	220	PF00018	0.490
LIG_SH3_3	292	298	PF00018	0.846
LIG_SH3_3	328	334	PF00018	0.623
LIG_SH3_3	353	359	PF00018	0.622
LIG_SH3_3	85	91	PF00018	0.806
LIG_SUMO_SIM_anti_2	41	49	PF11976	0.464
LIG_TRAF2_1	60	63	PF00917	0.689
LIG_WW_3	333	337	PF00397	0.607
MOD_CDC14_SPxK_1	114	117	PF00782	0.625
MOD_CDC14_SPxK_1	199	202	PF00782	0.589
MOD_CDK_SPxK_1	111	117	PF00069	0.628
MOD_CDK_SPxK_1	196	202	PF00069	0.584
MOD_CDK_SPxK_1	265	271	PF00069	0.845
MOD_CDK_SPxxK_3	57	64	PF00069	0.681
MOD_CK1_1	181	187	PF00069	0.590
MOD_CK1_1	275	281	PF00069	0.800
MOD_CK1_1	315	321	PF00069	0.632
MOD_CK1_1	349	355	PF00069	0.688
MOD_CK1_1	96	102	PF00069	0.835
MOD_CK2_1	204	210	PF00069	0.842
MOD_CK2_1	254	260	PF00069	0.631
MOD_CK2_1	316	322	PF00069	0.630
MOD_CK2_1	32	38	PF00069	0.496
MOD_CK2_1	57	63	PF00069	0.690
MOD_CK2_1	73	79	PF00069	0.700
MOD_GlcNHglycan	179	183	PF01048	0.764
MOD_GlcNHglycan	185	188	PF01048	0.787
MOD_GlcNHglycan	190	193	PF01048	0.709
MOD_GlcNHglycan	274	277	PF01048	0.606
MOD_GlcNHglycan	283	286	PF01048	0.550
MOD_GlcNHglycan	314	317	PF01048	0.643
MOD_GlcNHglycan	34	37	PF01048	0.491
MOD_GlcNHglycan	348	351	PF01048	0.645
MOD_GlcNHglycan	371	375	PF01048	0.790
MOD_GlcNHglycan	98	101	PF01048	0.616
MOD_GSK3_1	111	118	PF00069	0.592
MOD_GSK3_1	162	169	PF00069	0.642
MOD_GSK3_1	177	184	PF00069	0.624
MOD_GSK3_1	237	244	PF00069	0.688
MOD_GSK3_1	277	284	PF00069	0.720
MOD_GSK3_1	287	294	PF00069	0.804
MOD_GSK3_1	312	319	PF00069	0.639
MOD_GSK3_1	32	39	PF00069	0.494
MOD_GSK3_1	322	329	PF00069	0.578
MOD_GSK3_1	345	352	PF00069	0.766
MOD_GSK3_1	354	361	PF00069	0.799
MOD_GSK3_1	393	400	PF00069	0.808
MOD_GSK3_1	92	99	PF00069	0.771
MOD_N-GLC_1	171	176	PF02516	0.622
MOD_N-GLC_1	350	355	PF02516	0.639
MOD_NEK2_1	116	121	PF00069	0.639
MOD_NEK2_1	164	169	PF00069	0.653
MOD_NEK2_1	228	233	PF00069	0.827
MOD_NEK2_1	73	78	PF00069	0.697
MOD_PIKK_1	222	228	PF00454	0.586
MOD_PIKK_1	299	305	PF00454	0.628
MOD_PIKK_1	358	364	PF00454	0.815
MOD_PK_1	336	342	PF00069	0.624
MOD_PKA_2	116	122	PF00069	0.639
MOD_PKA_2	13	19	PF00069	0.546
MOD_PKA_2	335	341	PF00069	0.623
MOD_Plk_1	241	247	PF00069	0.621
MOD_Plk_4	228	234	PF00069	0.607
MOD_ProDKin_1	111	117	PF00069	0.861
MOD_ProDKin_1	141	147	PF00069	0.632
MOD_ProDKin_1	153	159	PF00069	0.681
MOD_ProDKin_1	196	202	PF00069	0.584
MOD_ProDKin_1	209	215	PF00069	0.633
MOD_ProDKin_1	265	271	PF00069	0.845
MOD_ProDKin_1	27	33	PF00069	0.762
MOD_ProDKin_1	291	297	PF00069	0.861
MOD_ProDKin_1	316	322	PF00069	0.782
MOD_ProDKin_1	326	332	PF00069	0.767
MOD_ProDKin_1	57	63	PF00069	0.690
MOD_SUMO_rev_2	373	382	PF00179	0.695
TRG_DiLeu_BaEn_4	62	68	PF01217	0.695
TRG_DiLeu_LyEn_5	210	215	PF01217	0.616
TRG_ENDOCYTIC_2	229	232	PF00928	0.831
TRG_ENDOCYTIC_2	66	69	PF00928	0.706
TRG_Pf-PMV_PEXEL_1	391	395	PF00026	0.579
TRG_Pf-PMV_PEXEL_1	65	70	PF00026	0.708

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4H327	Leishmania braziliensis	51%	100%