Plus3 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AJ92_LEIMU

TriTrypDb:

LmxM.01.0060

Length:

251

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 7
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AJ92

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AJ92

PDB structure(s): 7aih_As , 7am2_As , 7ane_As

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	157	159	PF00675	0.500
CLV_NRD_NRD_1	185	187	PF00675	0.642
CLV_NRD_NRD_1	199	201	PF00675	0.594
CLV_NRD_NRD_1	2	4	PF00675	0.592
CLV_NRD_NRD_1	59	61	PF00675	0.442
CLV_PCSK_FUR_1	158	162	PF00082	0.488
CLV_PCSK_KEX2_1	160	162	PF00082	0.478
CLV_PCSK_KEX2_1	180	182	PF00082	0.303
CLV_PCSK_KEX2_1	2	4	PF00082	0.567
CLV_PCSK_KEX2_1	59	61	PF00082	0.442
CLV_PCSK_PC1ET2_1	160	162	PF00082	0.478
CLV_PCSK_PC1ET2_1	180	182	PF00082	0.303
CLV_PCSK_SKI1_1	196	200	PF00082	0.568
DEG_APCC_DBOX_1	59	67	PF00400	0.445
DEG_Nend_UBRbox_1	1	4	PF02207	0.570
DOC_CDC14_PxL_1	1	9	PF14671	0.548
DOC_CKS1_1	133	138	PF01111	0.477
DOC_MAPK_gen_1	59	66	PF00069	0.439
DOC_USP7_MATH_1	17	21	PF00917	0.689
DOC_USP7_MATH_1	175	179	PF00917	0.546
DOC_USP7_MATH_1	36	40	PF00917	0.424
DOC_USP7_UBL2_3	202	206	PF12436	0.503
DOC_WW_Pin1_4	132	137	PF00397	0.467
DOC_WW_Pin1_4	208	213	PF00397	0.576
DOC_WW_Pin1_4	70	75	PF00397	0.422
LIG_14-3-3_CanoR_1	174	178	PF00244	0.622
LIG_14-3-3_CanoR_1	46	54	PF00244	0.512
LIG_Clathr_ClatBox_1	63	67	PF01394	0.456
LIG_FHA_1	7	13	PF00498	0.511
LIG_FHA_1	87	93	PF00498	0.449
LIG_FHA_2	174	180	PF00498	0.573
LIG_FHA_2	53	59	PF00498	0.462
LIG_LIR_Nem_3	58	64	PF02991	0.437
LIG_SH3_3	32	38	PF00018	0.544
LIG_UBA3_1	133	138	PF00899	0.525
LIG_UBA3_1	154	160	PF00899	0.537
LIG_WW_3	247	251	PF00397	0.801
MOD_CDK_SPxK_1	132	138	PF00069	0.474
MOD_CK1_1	20	26	PF00069	0.642
MOD_GlcNHglycan	141	145	PF01048	0.563
MOD_GlcNHglycan	19	22	PF01048	0.690
MOD_GlcNHglycan	243	246	PF01048	0.732
MOD_GlcNHglycan	25	28	PF01048	0.741
MOD_GlcNHglycan	38	41	PF01048	0.440
MOD_GlcNHglycan	50	53	PF01048	0.567
MOD_GSK3_1	145	152	PF00069	0.640
MOD_GSK3_1	15	22	PF00069	0.691
MOD_GSK3_1	48	55	PF00069	0.488
MOD_NEK2_1	188	193	PF00069	0.567
MOD_PIKK_1	145	151	PF00454	0.699
MOD_PKA_2	173	179	PF00069	0.581
MOD_PKA_2	188	194	PF00069	0.459
MOD_PKA_2	216	222	PF00069	0.657
MOD_PKA_2	223	229	PF00069	0.715
MOD_PKA_2	241	247	PF00069	0.555
MOD_PKA_2	52	58	PF00069	0.472
MOD_Plk_1	181	187	PF00069	0.496
MOD_Plk_2-3	173	179	PF00069	0.624
MOD_Plk_4	73	79	PF00069	0.426
MOD_ProDKin_1	132	138	PF00069	0.474
MOD_ProDKin_1	208	214	PF00069	0.582
MOD_ProDKin_1	70	76	PF00069	0.418
TRG_DiLeu_BaLyEn_6	7	12	PF01217	0.520
TRG_ER_diArg_1	1	3	PF00400	0.599
TRG_ER_diArg_1	59	61	PF00400	0.442
TRG_Pf-PMV_PEXEL_1	161	166	PF00026	0.559
TRG_Pf-PMV_PEXEL_1	186	190	PF00026	0.513
TRG_Pf-PMV_PEXEL_1	201	205	PF00026	0.609
TRG_Pf-PMV_PEXEL_1	90	94	PF00026	0.432

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6N8	Leptomonas seymouri	77%	100%
A0A0S4JMA4	Bodo saltans	63%	100%
A0A451EJ64	Leishmania donovani	92%	100%
A4H340	Leishmania braziliensis	76%	94%
A4HRC7	Leishmania infantum	92%	100%
C9ZXG9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	73%	100%
E9ABZ5	Leishmania major	87%	99%