Putative serine palmitoyltransferase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

serine palmitoyltransferase, putative

Species:

Leishmania braziliensis

UniProt:

E9AIW0_LEIBR

TriTrypDb:

LbrM.34.0360 , LBRM2903_340008500

Length:

540

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0002178	palmitoyltransferase complex	4	1
GO:0005783	endoplasmic reticulum	5	1
GO:0017059	serine C-palmitoyltransferase complex	4	1
GO:0031211	endoplasmic reticulum palmitoyltransferase complex	3	1
GO:0032991	protein-containing complex	1	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	7
GO:0140534	endoplasmic reticulum protein-containing complex	2	1
GO:1902494	catalytic complex	2	1
GO:1990234	transferase complex	3	1
GO:0016020	membrane	2	6

Expansion

Sequence features

E9AIW0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AIW0

Function

Biological processes
Term	Name	Level	Count
GO:0008152	metabolic process	1	12
GO:0009058	biosynthetic process	2	12
GO:0006066	alcohol metabolic process	3	1
GO:0006629	lipid metabolic process	3	1
GO:0006643	membrane lipid metabolic process	4	1
GO:0006665	sphingolipid metabolic process	4	1
GO:0006670	sphingosine metabolic process	6	1
GO:0006672	ceramide metabolic process	4	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008610	lipid biosynthetic process	4	1
GO:0009987	cellular process	1	1
GO:0019751	polyol metabolic process	4	1
GO:0030148	sphingolipid biosynthetic process	5	1
GO:0034311	diol metabolic process	5	1
GO:0034312	diol biosynthetic process	6	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0043603	amide metabolic process	3	1
GO:0043604	amide biosynthetic process	4	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044249	cellular biosynthetic process	3	1
GO:0044255	cellular lipid metabolic process	3	1
GO:0044271	cellular nitrogen compound biosynthetic process	4	1
GO:0044281	small molecule metabolic process	2	1
GO:0044283	small molecule biosynthetic process	3	1
GO:0046165	alcohol biosynthetic process	4	1
GO:0046173	polyol biosynthetic process	5	1
GO:0046467	membrane lipid biosynthetic process	4	1
GO:0046512	sphingosine biosynthetic process	5	1
GO:0046513	ceramide biosynthetic process	5	1
GO:0046519	sphingoid metabolic process	5	1
GO:0046520	sphingoid biosynthetic process	6	1
GO:0071704	organic substance metabolic process	2	1
GO:1901564	organonitrogen compound metabolic process	3	1
GO:1901566	organonitrogen compound biosynthetic process	4	1
GO:1901576	organic substance biosynthetic process	3	1
GO:1901615	organic hydroxy compound metabolic process	3	1
GO:1901617	organic hydroxy compound biosynthetic process	4	1

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	12
GO:0004758	serine C-palmitoyltransferase activity	7	8
GO:0005488	binding	1	12
GO:0016408	C-acyltransferase activity	5	8
GO:0016409	palmitoyltransferase activity	5	8
GO:0016454	C-palmitoyltransferase activity	6	8
GO:0016740	transferase activity	2	12
GO:0016746	acyltransferase activity	3	8
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	4	8
GO:0019842	vitamin binding	3	12
GO:0030170	pyridoxal phosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0070279	vitamin B6 binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	187	191	PF00656	0.512
CLV_C14_Caspase3-7	34	38	PF00656	0.474
CLV_MEL_PAP_1	145	151	PF00089	0.277
CLV_NRD_NRD_1	125	127	PF00675	0.297
CLV_NRD_NRD_1	448	450	PF00675	0.510
CLV_PCSK_KEX2_1	125	127	PF00082	0.297
CLV_PCSK_KEX2_1	24	26	PF00082	0.625
CLV_PCSK_KEX2_1	306	308	PF00082	0.528
CLV_PCSK_KEX2_1	326	328	PF00082	0.353
CLV_PCSK_KEX2_1	435	437	PF00082	0.439
CLV_PCSK_KEX2_1	448	450	PF00082	0.467
CLV_PCSK_PC1ET2_1	24	26	PF00082	0.625
CLV_PCSK_PC1ET2_1	306	308	PF00082	0.519
CLV_PCSK_PC1ET2_1	326	328	PF00082	0.353
CLV_PCSK_PC1ET2_1	435	437	PF00082	0.446
CLV_PCSK_PC7_1	121	127	PF00082	0.277
CLV_PCSK_SKI1_1	248	252	PF00082	0.440
CLV_PCSK_SKI1_1	336	340	PF00082	0.557
CLV_PCSK_SKI1_1	422	426	PF00082	0.533
CLV_PCSK_SKI1_1	438	442	PF00082	0.512
CLV_PCSK_SKI1_1	449	453	PF00082	0.513
CLV_PCSK_SKI1_1	527	531	PF00082	0.530
DEG_APCC_DBOX_1	447	455	PF00400	0.276
DEG_ODPH_VHL_1	409	420	PF01847	0.312
DEG_SPOP_SBC_1	57	61	PF00917	0.351
DOC_CDC14_PxL_1	239	247	PF14671	0.243
DOC_CKS1_1	497	502	PF01111	0.219
DOC_CYCLIN_RxL_1	332	343	PF00134	0.255
DOC_CYCLIN_RxL_1	419	428	PF00134	0.145
DOC_CYCLIN_RxL_1	446	453	PF00134	0.153
DOC_MAPK_gen_1	286	294	PF00069	0.311
DOC_MAPK_gen_1	303	312	PF00069	0.271
DOC_MAPK_gen_1	332	340	PF00069	0.209
DOC_MAPK_gen_1	448	456	PF00069	0.280
DOC_MAPK_MEF2A_6	162	169	PF00069	0.513
DOC_MAPK_MEF2A_6	303	312	PF00069	0.276
DOC_MAPK_MEF2A_6	448	456	PF00069	0.276
DOC_MAPK_NFAT4_5	449	457	PF00069	0.276
DOC_PP1_RVXF_1	334	341	PF00149	0.255
DOC_PP1_RVXF_1	503	509	PF00149	0.219
DOC_PP2B_LxvP_1	409	412	PF13499	0.220
DOC_PP4_FxxP_1	131	134	PF00568	0.496
DOC_SPAK_OSR1_1	507	511	PF12202	0.209
DOC_USP7_MATH_1	134	138	PF00917	0.477
DOC_USP7_MATH_1	198	202	PF00917	0.433
DOC_USP7_UBL2_3	332	336	PF12436	0.255
DOC_WW_Pin1_4	13	18	PF00397	0.448
DOC_WW_Pin1_4	178	183	PF00397	0.429
DOC_WW_Pin1_4	43	48	PF00397	0.529
DOC_WW_Pin1_4	461	466	PF00397	0.214
DOC_WW_Pin1_4	496	501	PF00397	0.219
LIG_14-3-3_CanoR_1	476	483	PF00244	0.293
LIG_ActinCP_TwfCPI_2	131	141	PF01115	0.579
LIG_APCC_ABBA_1	402	407	PF00400	0.219
LIG_APCC_ABBAyCdc20_2	336	342	PF00400	0.255
LIG_APCC_ABBAyCdc20_2	530	536	PF00400	0.326
LIG_BIR_II_1	1	5	PF00653	0.437
LIG_BRCT_BRCA1_1	39	43	PF00533	0.476
LIG_BRCT_BRCA1_1	443	447	PF00533	0.233
LIG_BRCT_BRCA1_2	39	45	PF00533	0.468
LIG_Clathr_ClatBox_1	338	342	PF01394	0.209
LIG_deltaCOP1_diTrp_1	116	123	PF00928	0.481
LIG_eIF4E_1	496	502	PF01652	0.202
LIG_FHA_1	1	7	PF00498	0.453
LIG_FHA_1	158	164	PF00498	0.432
LIG_FHA_1	179	185	PF00498	0.415
LIG_FHA_1	399	405	PF00498	0.362
LIG_FHA_1	497	503	PF00498	0.243
LIG_FHA_1	520	526	PF00498	0.276
LIG_FHA_2	513	519	PF00498	0.211
LIG_FHA_2	57	63	PF00498	0.479
LIG_LIR_Apic_2	129	134	PF02991	0.474
LIG_LIR_Gen_1	171	178	PF02991	0.411
LIG_LIR_Gen_1	216	223	PF02991	0.476
LIG_LIR_Gen_1	279	288	PF02991	0.172
LIG_LIR_Gen_1	69	78	PF02991	0.253
LIG_LIR_Gen_1	91	98	PF02991	0.534
LIG_LIR_LC3C_4	453	458	PF02991	0.255
LIG_LIR_Nem_3	114	118	PF02991	0.581
LIG_LIR_Nem_3	171	177	PF02991	0.411
LIG_LIR_Nem_3	216	222	PF02991	0.498
LIG_LIR_Nem_3	237	242	PF02991	0.263
LIG_LIR_Nem_3	279	284	PF02991	0.218
LIG_LIR_Nem_3	301	305	PF02991	0.317
LIG_LIR_Nem_3	376	382	PF02991	0.218
LIG_LIR_Nem_3	69	74	PF02991	0.248
LIG_LIR_Nem_3	75	81	PF02991	0.248
LIG_LIR_Nem_3	91	96	PF02991	0.471
LIG_MLH1_MIPbox_1	443	447	PF16413	0.233
LIG_NRBOX	420	426	PF00104	0.312
LIG_Pex14_1	119	123	PF04695	0.475
LIG_Pex14_2	115	119	PF04695	0.474
LIG_Pex14_2	235	239	PF04695	0.243
LIG_Pex14_2	375	379	PF04695	0.209
LIG_PTB_Apo_2	117	124	PF02174	0.558
LIG_PTB_Apo_2	528	535	PF02174	0.205
LIG_PTB_Phospho_1	528	534	PF10480	0.208
LIG_REV1ctd_RIR_1	444	453	PF16727	0.233
LIG_SH2_CRK	108	112	PF00017	0.541
LIG_SH2_CRK	124	128	PF00017	0.470
LIG_SH2_CRK	172	176	PF00017	0.409
LIG_SH2_CRK	305	309	PF00017	0.322
LIG_SH2_CRK	335	339	PF00017	0.209
LIG_SH2_CRK	93	97	PF00017	0.614
LIG_SH2_GRB2like	118	121	PF00017	0.561
LIG_SH2_SRC	108	111	PF00017	0.649
LIG_SH2_STAT5	159	162	PF00017	0.537
LIG_SH2_STAT5	174	177	PF00017	0.409
LIG_SH2_STAT5	287	290	PF00017	0.243
LIG_SH2_STAT5	385	388	PF00017	0.213
LIG_SH2_STAT5	395	398	PF00017	0.327
LIG_SH2_STAT5	532	535	PF00017	0.369
LIG_SH2_STAT5	77	80	PF00017	0.277
LIG_SH2_STAT5	93	96	PF00017	0.560
LIG_SH3_3	405	411	PF00018	0.255
LIG_SH3_3	41	47	PF00018	0.511
LIG_SH3_3	462	468	PF00018	0.209
LIG_SH3_3	491	497	PF00018	0.209
LIG_SUMO_SIM_anti_2	367	372	PF11976	0.208
LIG_SUMO_SIM_anti_2	522	528	PF11976	0.276
LIG_SUMO_SIM_par_1	307	313	PF11976	0.210
LIG_SUMO_SIM_par_1	455	464	PF11976	0.312
LIG_TRAF2_1	202	205	PF00917	0.495
LIG_TRAF2_1	28	31	PF00917	0.442
LIG_TRAF2_1	98	101	PF00917	0.496
LIG_WRC_WIRS_1	372	377	PF05994	0.209
LIG_WRPW_2	302	305	PF00400	0.312
MOD_CDK_SPK_2	13	18	PF00069	0.359
MOD_CK1_1	137	143	PF00069	0.471
MOD_CK1_1	378	384	PF00069	0.233
MOD_CK1_1	478	484	PF00069	0.320
MOD_CK1_1	69	75	PF00069	0.400
MOD_CK1_1	76	82	PF00069	0.415
MOD_CK2_1	295	301	PF00069	0.283
MOD_CK2_1	56	62	PF00069	0.469
MOD_GlcNHglycan	200	203	PF01048	0.233
MOD_GlcNHglycan	268	271	PF01048	0.433
MOD_GlcNHglycan	477	480	PF01048	0.521
MOD_GlcNHglycan	510	513	PF01048	0.409
MOD_GSK3_1	153	160	PF00069	0.499
MOD_GSK3_1	178	185	PF00069	0.429
MOD_GSK3_1	253	260	PF00069	0.214
MOD_GSK3_1	371	378	PF00069	0.240
MOD_GSK3_1	43	50	PF00069	0.497
MOD_GSK3_1	508	515	PF00069	0.216
MOD_GSK3_1	69	76	PF00069	0.261
MOD_GSK3_1	7	14	PF00069	0.374
MOD_N-GLC_1	153	158	PF02516	0.285
MOD_N-GLC_1	257	262	PF02516	0.426
MOD_N-GLC_1	37	42	PF02516	0.717
MOD_N-GLC_1	442	447	PF02516	0.512
MOD_NEK2_1	1	6	PF00069	0.362
MOD_NEK2_1	11	16	PF00069	0.505
MOD_NEK2_1	157	162	PF00069	0.533
MOD_NEK2_1	206	211	PF00069	0.516
MOD_NEK2_1	253	258	PF00069	0.219
MOD_NEK2_1	371	376	PF00069	0.215
MOD_NEK2_1	508	513	PF00069	0.217
MOD_NEK2_1	535	540	PF00069	0.339
MOD_PIKK_1	37	43	PF00454	0.423
MOD_PKA_2	137	143	PF00069	0.471
MOD_PKA_2	147	153	PF00069	0.485
MOD_PKA_2	266	272	PF00069	0.209
MOD_PKA_2	475	481	PF00069	0.255
MOD_Plk_1	153	159	PF00069	0.519
MOD_Plk_1	257	263	PF00069	0.233
MOD_Plk_1	37	43	PF00069	0.486
MOD_Plk_1	397	403	PF00069	0.271
MOD_Plk_1	441	447	PF00069	0.219
MOD_Plk_4	207	213	PF00069	0.494
MOD_Plk_4	258	264	PF00069	0.235
MOD_Plk_4	416	422	PF00069	0.276
MOD_Plk_4	442	448	PF00069	0.296
MOD_Plk_4	66	72	PF00069	0.223
MOD_Plk_4	73	79	PF00069	0.270
MOD_ProDKin_1	13	19	PF00069	0.444
MOD_ProDKin_1	178	184	PF00069	0.429
MOD_ProDKin_1	43	49	PF00069	0.529
MOD_ProDKin_1	461	467	PF00069	0.214
MOD_ProDKin_1	496	502	PF00069	0.219
MOD_SUMO_for_1	23	26	PF00179	0.478
MOD_SUMO_rev_2	297	304	PF00179	0.255
MOD_SUMO_rev_2	31	40	PF00179	0.498
MOD_SUMO_rev_2	359	368	PF00179	0.218
TRG_DiLeu_BaEn_2	217	223	PF01217	0.512
TRG_DiLeu_BaLyEn_6	388	393	PF01217	0.153
TRG_DiLeu_BaLyEn_6	497	502	PF01217	0.212
TRG_ENDOCYTIC_2	108	111	PF00928	0.575
TRG_ENDOCYTIC_2	124	127	PF00928	0.477
TRG_ENDOCYTIC_2	172	175	PF00928	0.409
TRG_ENDOCYTIC_2	305	308	PF00928	0.306
TRG_ENDOCYTIC_2	335	338	PF00928	0.209
TRG_ENDOCYTIC_2	532	535	PF00928	0.369
TRG_ENDOCYTIC_2	77	80	PF00928	0.260
TRG_ENDOCYTIC_2	93	96	PF00928	0.456
TRG_ER_diArg_1	124	126	PF00400	0.467
TRG_ER_diArg_1	447	449	PF00400	0.304
TRG_ER_diArg_1	505	508	PF00400	0.251
TRG_NES_CRM1_1	524	536	PF08389	0.298
TRG_NLS_MonoExtC_3	331	336	PF00514	0.255
TRG_NLS_MonoExtN_4	332	337	PF00514	0.255
TRG_Pf-PMV_PEXEL_1	286	290	PF00026	0.476
TRG_Pf-PMV_PEXEL_1	438	442	PF00026	0.467
TRG_Pf-PMV_PEXEL_1	449	453	PF00026	0.435

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0H3C7E9	Caulobacter vibrioides (strain NA1000 / CB15N)	31%	100%
A0A0N0P413	Leptomonas seymouri	81%	100%
A0A0S4JWE9	Bodo saltans	57%	100%
A0A0S4KHT5	Bodo saltans	30%	100%
A0A1X0NJD6	Trypanosomatidae	62%	96%
A0A1X0NWE6	Trypanosomatidae	29%	100%
A0A3G9HHK2	Alternaria alternata	26%	67%
A0A3Q8IP00	Leishmania donovani	87%	100%
A0A3R7MV02	Trypanosoma rangeli	29%	100%
A0A422NN79	Trypanosoma rangeli	67%	97%
A0KIC7	Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049)	30%	100%
A0L3L7	Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1)	30%	100%
A0QX65	Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)	25%	100%
A0RIB9	Bacillus thuringiensis (strain Al Hakam)	30%	100%
A1A918	Escherichia coli O1:K1 / APEC	27%	100%
A1JS67	Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)	28%	100%
A1K6Q1	Azoarcus sp. (strain BH72)	23%	100%
A1TTV0	Acidovorax citrulli (strain AAC00-1)	25%	100%
A1U4B1	Marinobacter nauticus (strain ATCC 700491 / DSM 11845 / VT8)	27%	100%
A1UHM3	Mycobacterium sp. (strain KMS)	26%	100%
A1V819	Burkholderia mallei (strain SAVP1)	29%	100%
A1VUJ6	Polaromonas naphthalenivorans (strain CJ2)	26%	100%
A2S7R1	Burkholderia mallei (strain NCTC 10229)	29%	100%
A3MNG3	Burkholderia mallei (strain NCTC 10247)	29%	100%
A3N522	Burkholderia pseudomallei (strain 668)	29%	100%
A3NQS3	Burkholderia pseudomallei (strain 1106a)	29%	100%
A3Q146	Mycobacterium sp. (strain JLS)	26%	100%
A4IAT3	Leishmania infantum	87%	100%
A4SPR6	Aeromonas salmonicida (strain A449)	29%	100%
A4T9L3	Mycolicibacterium gilvum (strain PYR-GCK)	24%	100%
A4TNQ5	Yersinia pestis (strain Pestoides F)	24%	100%
A4VR87	Pseudomonas stutzeri (strain A1501)	28%	100%
A6QLI6	Bos taurus	26%	83%
A6SU64	Janthinobacterium sp. (strain Marseille)	27%	100%
A6T6L6	Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)	26%	100%
A6TU88	Alkaliphilus metalliredigens (strain QYMF)	32%	100%
A6UQL9	Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)	24%	100%
A6UYW1	Pseudomonas aeruginosa (strain PA7)	27%	100%
A7BFV8	Bacteriovorax stolpii	32%	100%
A7FKM8	Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)	24%	100%
A7GSE1	Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)	31%	100%
A7HG96	Anaeromyxobacter sp. (strain Fw109-5)	29%	100%
A7LXM2	Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153)	30%	100%
A7MJ02	Cronobacter sakazakii (strain ATCC BAA-894)	26%	100%
A7Z4X1	Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42)	30%	100%
A7Z5B4	Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42)	28%	100%
A7ZJI5	Escherichia coli O139:H28 (strain E24377A / ETEC)	27%	100%
A7ZY32	Escherichia coli O9:H4 (strain HS)	28%	100%
A8AJ11	Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)	26%	100%
A8FDG9	Bacillus pumilus (strain SAFR-032)	28%	100%
A8GBC6	Serratia proteamaculans (strain 568)	27%	100%
A8MEX7	Alkaliphilus oremlandii (strain OhILAs)	29%	100%
A9BGL0	Petrotoga mobilis (strain DSM 10674 / SJ95)	31%	100%
A9BV10	Delftia acidovorans (strain DSM 14801 / SPH-1)	27%	100%
A9HVE9	Bordetella petrii (strain ATCC BAA-461 / DSM 12804 / CCUG 43448)	26%	100%
A9MJE5	Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)	28%	100%
A9MTI7	Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)	27%	100%
A9R3C9	Yersinia pestis bv. Antiqua (strain Angola)	24%	100%
A9VG56	Bacillus mycoides (strain KBAB4)	30%	100%
A9W106	Methylorubrum extorquens (strain PA1)	27%	100%
B0C205	Acaryochloris marina (strain MBIC 11017)	28%	100%
B0JQZ0	Microcystis aeruginosa (strain NIES-843 / IAM M-2473)	28%	100%
B0SZS9	Caulobacter sp. (strain K31)	24%	100%
B0UKC8	Methylobacterium sp. (strain 4-46)	28%	100%
B1IXJ2	Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)	28%	100%
B1JE54	Pseudomonas putida (strain W619)	27%	100%
B1JSS3	Yersinia pseudotuberculosis serotype O:3 (strain YPIII)	24%	100%
B1LM67	Escherichia coli (strain SMS-3-5 / SECEC)	27%	100%
B1X7A6	Escherichia coli (strain K12 / DH10B)	27%	100%
B1XL23	Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6)	28%	100%
B1YMC6	Exiguobacterium sibiricum (strain DSM 17290 / CIP 109462 / JCM 13490 / 255-15)	31%	100%
B2AG98	Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CCUG 44338 / CIP 107171 / LMG 19424 / R1)	27%	100%
B2FLM5	Stenotrophomonas maltophilia (strain K279a)	26%	100%
B2J1W1	Nostoc punctiforme (strain ATCC 29133 / PCC 73102)	27%	100%
B2JKH6	Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815)	26%	100%
B2K8T1	Yersinia pseudotuberculosis serotype IB (strain PB1/+)	24%	100%
B2SWS7	Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN)	27%	100%
B2TVF4	Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)	27%	100%
B2VBT8	Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99)	26%	100%
B3PI88	Cellvibrio japonicus (strain Ueda107)	29%	100%
B4ESU4	Proteus mirabilis (strain HI4320)	24%	100%
B4SM82	Stenotrophomonas maltophilia (strain R551-3)	25%	100%
B4SZJ8	Salmonella newport (strain SL254)	26%	100%
B4TC49	Salmonella heidelberg (strain SL476)	27%	100%
B4TQU0	Salmonella schwarzengrund (strain CVM19633)	26%	100%
B4UCB1	Anaeromyxobacter sp. (strain K)	29%	100%
B5BC30	Salmonella paratyphi A (strain AKU_12601)	26%	100%
B5ELF7	Acidithiobacillus ferrooxidans (strain ATCC 53993 / BNL-5-31)	27%	100%
B5EUP9	Aliivibrio fischeri (strain MJ11)	26%	100%
B5F073	Salmonella agona (strain SL483)	27%	100%
B5FP62	Salmonella dublin (strain CT_02021853)	26%	100%
B5QX66	Salmonella enteritidis PT4 (strain P125109)	26%	100%
B5R762	Salmonella gallinarum (strain 287/91 / NCTC 13346)	26%	100%
B5YRL5	Escherichia coli O157:H7 (strain EC4115 / EHEC)	27%	100%
B6ESC6	Aliivibrio salmonicida (strain LFI1238)	27%	100%
B6I7T0	Escherichia coli (strain SE11)	27%	100%
B7HAZ0	Bacillus cereus (strain B4264)	29%	100%
B7HNN4	Bacillus cereus (strain AH187)	31%	100%
B7IWN1	Bacillus cereus (strain G9842)	29%	100%
B7J3Y7	Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455)	27%	100%
B7JLX2	Bacillus cereus (strain AH820)	30%	100%
B7K0L9	Rippkaea orientalis (strain PCC 8801)	28%	100%
B7KD70	Gloeothece citriformis (strain PCC 7424)	28%	100%
B7L0L2	Methylorubrum extorquens (strain CM4 / NCIMB 13688)	27%	100%
B7LC58	Escherichia coli (strain 55989 / EAEC)	27%	100%
B7LJY7	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)	27%	100%
B7M748	Escherichia coli O8 (strain IAI1)	26%	100%
B7MGN4	Escherichia coli O45:K1 (strain S88 / ExPEC)	27%	100%
B7MQM9	Escherichia coli O81 (strain ED1a)	27%	100%
B7ULX3	Escherichia coli O127:H6 (strain E2348/69 / EPEC)	28%	100%
B7V486	Pseudomonas aeruginosa (strain LESB58)	27%	100%
B7VH15	Vibrio atlanticus (strain LGP32)	25%	100%
B8IBW2	Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060)	29%	100%
B9IWY0	Bacillus cereus (strain Q1)	31%	100%
C0PWY3	Salmonella paratyphi C (strain RKS4594)	26%	100%
C4LK80	Corynebacterium kroppenstedtii (strain DSM 44385 / JCM 11950 / CIP 105744 / CCUG 35717)	26%	75%
C9ZW82	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	100%
D0A2C6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	58%	97%
D4A2H2	Rattus norvegicus	26%	100%
D4H9Y2	Cutibacterium acnes (strain SK137)	26%	81%
E9AEK9	Leishmania major	86%	100%
E9B5S0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
O15269	Homo sapiens	26%	100%
O15270	Homo sapiens	48%	96%
O31777	Bacillus subtilis (strain 168)	31%	100%
O35704	Mus musculus	26%	100%
O54694	Cricetulus griseus	47%	96%
O54695	Cricetulus griseus	26%	100%
O59682	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	28%	100%
O75600	Homo sapiens	29%	100%
O88986	Mus musculus	29%	100%
O94069	Candida albicans (strain SC5314 / ATCC MYA-2876)	28%	96%
P07997	Gallus gallus	26%	85%
P08080	Rhizobium meliloti (strain 1021)	28%	100%
P09950	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	99%
P0AB77	Escherichia coli (strain K12)	31%	100%
P0AB78	Escherichia coli O157:H7	31%	100%
P0AB79	Shigella flexneri	31%	100%
P12998	Escherichia coli (strain K12)	27%	100%
P13195	Rattus norvegicus	24%	84%
P13196	Homo sapiens	26%	84%
P18079	Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)	27%	100%
P18080	Gallus gallus	28%	100%
P22806	Lysinibacillus sphaericus	27%	100%
P26505	Rhizobium radiobacter	26%	100%
P36570	Serratia marcescens	25%	100%
P37419	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	31%	100%
P38092	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	26%	83%
P40970	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	43%	96%
P43089	Paracoccus denitrificans (strain Pd 1222)	28%	100%
P43090	Opsanus tau	27%	93%
P43091	Opsanus tau	25%	86%
P48241	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	41%	96%
P53556	Bacillus subtilis (strain 168)	27%	100%
P74770	Synechocystis sp. (strain PCC 6803 / Kazusa)	28%	100%
P78698	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	27%	95%
P97363	Mus musculus	47%	96%
Q02TR5	Pseudomonas aeruginosa (strain UCBPP-PA14)	27%	100%
Q04512	Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.)	28%	100%
Q06965	Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.)	26%	100%
Q09925	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	39%	90%
Q0AE73	Nitrosomonas eutropha (strain DSM 101675 / C91 / Nm57)	27%	100%
Q0APZ9	Maricaulis maris (strain MCS10)	27%	100%
Q0BUV6	Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)	24%	100%
Q0KF88	Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)	26%	100%
Q0P5L8	Bos taurus	28%	100%
Q0T6I4	Shigella flexneri serotype 5b (strain 8401)	27%	100%
Q0TJS2	Escherichia coli O6:K15:H31 (strain 536 / UPEC)	27%	100%
Q0VMD1	Alcanivorax borkumensis (strain ATCC 700651 / DSM 11573 / NCIMB 13689 / SK2)	26%	100%
Q10P01	Oryza sativa subsp. japonica	26%	100%
Q119K2	Trichodesmium erythraeum (strain IMS101)	27%	100%
Q12D74	Polaromonas sp. (strain JS666 / ATCC BAA-500)	24%	100%
Q12F38	Polaromonas sp. (strain JS666 / ATCC BAA-500)	26%	100%
Q146K3	Paraburkholderia xenovorans (strain LB400)	27%	100%
Q1B7F0	Mycobacterium sp. (strain MCS)	26%	100%
Q1C946	Yersinia pestis bv. Antiqua (strain Antiqua)	24%	100%
Q1CFQ4	Yersinia pestis bv. Antiqua (strain Nepal516)	24%	100%
Q1DCV8	Myxococcus xanthus (strain DK1622)	29%	100%
Q1GZA7	Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875)	25%	100%
Q1I3N7	Pseudomonas entomophila (strain L48)	28%	100%
Q1LS75	Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)	26%	100%
Q1QYD6	Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11)	27%	100%
Q1REF4	Escherichia coli (strain UTI89 / UPEC)	27%	100%
Q20375	Caenorhabditis elegans	45%	97%
Q21FY4	Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024)	29%	100%
Q2R3K3	Oryza sativa subsp. japonica	46%	100%
Q2SBD5	Hahella chejuensis (strain KCTC 2396)	28%	100%
Q2W3L2	Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)	30%	100%
Q31E54	Hydrogenovibrio crunogenus (strain DSM 25203 / XCL-2)	28%	100%
Q324B6	Shigella boydii serotype 4 (strain Sb227)	27%	100%
Q32I45	Shigella dysenteriae serotype 1 (strain Sd197)	27%	100%
Q3B7D2	Rattus norvegicus	47%	96%
Q3JWR6	Burkholderia pseudomallei (strain 1710b)	28%	100%
Q3K5P2	Pseudomonas fluorescens (strain Pf0-1)	27%	100%
Q3M9A4	Trichormus variabilis (strain ATCC 29413 / PCC 7937)	29%	100%
Q3MHG1	Bos taurus	28%	100%
Q3SLX9	Thiobacillus denitrificans (strain ATCC 25259)	25%	100%
Q3Z408	Shigella sonnei (strain Ss046)	27%	100%
Q3ZC31	Bos taurus	28%	92%
Q477A3	Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197)	24%	100%
Q47829	Pseudescherichia vulneris	26%	100%
Q47C04	Dechloromonas aromatica (strain RCB)	28%	100%
Q48CS2	Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6)	28%	100%
Q4K4T3	Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)	27%	100%
Q4ZMA9	Pseudomonas syringae pv. syringae (strain B728a)	29%	100%
Q54EX5	Dictyostelium discoideum	48%	100%
Q55FL5	Dictyostelium discoideum	24%	100%
Q57RG2	Salmonella choleraesuis (strain SC-B67)	26%	100%
Q5DZH9	Aliivibrio fischeri (strain ATCC 700601 / ES114)	27%	100%
Q5F6R6	Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)	25%	100%
Q5JK39	Oryza sativa subsp. japonica	46%	100%
Q5KY23	Geobacillus kaustophilus (strain HTA426)	30%	100%
Q5NZF5	Aromatoleum aromaticum (strain EbN1)	24%	100%
Q5PG49	Salmonella paratyphi A (strain ATCC 9150 / SARB42)	26%	100%
Q5R9T5	Pongo abelii	26%	100%
Q5SHZ8	Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)	34%	100%
Q5W264	Serratia sp. (strain ATCC 39006)	29%	83%
Q609V1	Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)	30%	100%
Q60HD1	Macaca fascicularis	26%	100%
Q62MX1	Burkholderia mallei (strain ATCC 23344)	29%	100%
Q63147	Rattus norvegicus	24%	92%
Q635G4	Bacillus cereus (strain ZK / E33L)	29%	100%
Q63Y23	Burkholderia pseudomallei (strain K96243)	29%	100%
Q66D66	Yersinia pseudotuberculosis serotype I (strain IP32953)	24%	100%
Q6A6M4	Cutibacterium acnes (strain DSM 16379 / KPA171202)	26%	83%
Q6BX71	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	28%	94%
Q6CCW0	Yarrowia lipolytica (strain CLIB 122 / E 150)	25%	96%
Q6D3C0	Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)	25%	100%
Q6FXE3	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	27%	100%
Q6HE48	Bacillus thuringiensis subsp. konkukian (strain 97-27)	30%	100%
Q6LPR3	Photobacterium profundum (strain SS9)	25%	100%
Q75DX7	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	27%	97%
Q7CH66	Yersinia pestis	24%	100%
Q7N6Q6	Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	24%	100%
Q7NNL4	Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)	28%	100%
Q7NPW2	Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)	28%	100%
Q7RVY5	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	28%	86%
Q7VL09	Haemophilus ducreyi (strain 35000HP / ATCC 700724)	28%	100%
Q7VWP1	Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)	29%	100%
Q7W9I4	Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)	28%	100%
Q7WH76	Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)	29%	100%
Q818X0	Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)	29%	100%
Q81MB0	Bacillus anthracis	30%	100%
Q81ZZ4	Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)	24%	100%
Q83S45	Shigella flexneri	27%	100%
Q87QN5	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	27%	100%
Q88A97	Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)	28%	100%
Q89AK6	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	27%	100%
Q8BG54	Mus musculus	41%	96%
Q8EM07	Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)	31%	100%
Q8FJQ2	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	28%	100%
Q8GW43	Arabidopsis thaliana	25%	100%
Q8KZM9	Bacillus subtilis subsp. natto	25%	100%
Q8RYL0	Oryza sativa subsp. japonica	47%	100%
Q8RYL1	Oryza sativa subsp. japonica	45%	100%
Q8VC19	Mus musculus	24%	84%
Q8X823	Escherichia coli O157:H7	27%	100%
Q8YZT3	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	28%	100%
Q8Z892	Salmonella typhi	26%	100%
Q8ZQQ7	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	27%	100%
Q92403	Agaricus bisporus	28%	87%
Q93UV0	Sphingomonas paucimobilis	27%	100%
Q9CJU0	Pasteurella multocida (strain Pm70)	26%	100%
Q9I617	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	27%	100%
Q9K625	Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)	31%	100%
Q9KSZ3	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	26%	100%
Q9LSZ9	Arabidopsis thaliana	46%	100%
Q9M304	Arabidopsis thaliana	46%	100%
Q9NUV7	Homo sapiens	47%	98%
Q9XVI6	Caenorhabditis elegans	41%	100%
V5BEA8	Trypanosoma cruzi	29%	100%
V5DJP6	Trypanosoma cruzi	61%	96%