Membrane-associated protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

E9AIV3_LEIBR

TriTrypDb:

LbrM.32.3841 , LBRM2903_320047700

Length:

114


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

E9AIV3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AIV3


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	76	78	PF00675	0.417
CLV_NRD_NRD_1	82	84	PF00675	0.436
CLV_PCSK_KEX2_1	81	83	PF00082	0.450
CLV_PCSK_PC7_1	77	83	PF00082	0.421
DOC_CYCLIN_yCln2_LP_2	57	63	PF00134	0.369
DOC_PP2B_LxvP_1	57	60	PF13499	0.344
DOC_USP7_MATH_1	62	66	PF00917	0.445
LIG_14-3-3_CanoR_1	82	91	PF00244	0.760
LIG_Actin_WH2_2	64	79	PF00022	0.485
LIG_BIR_II_1	1	5	PF00653	0.585
LIG_BRCT_BRCA1_1	64	68	PF00533	0.463
LIG_FHA_1	17	23	PF00498	0.696
LIG_FHA_1	52	58	PF00498	0.443
LIG_IRF3_LxIS_1	41	46	PF10401	0.444
LIG_LIR_Gen_1	24	34	PF02991	0.498
LIG_LIR_Gen_1	38	47	PF02991	0.444
LIG_LIR_Nem_3	24	29	PF02991	0.583
LIG_LIR_Nem_3	38	43	PF02991	0.444
LIG_LIR_Nem_3	65	71	PF02991	0.401
LIG_Pex14_2	26	30	PF04695	0.438
LIG_SH2_PTP2	40	43	PF00017	0.369
LIG_SH2_STAP1	93	97	PF00017	0.735
LIG_SH2_STAT5	40	43	PF00017	0.325
LIG_SH3_3	103	109	PF00018	0.723
MOD_CK1_1	12	18	PF00069	0.626
MOD_CK1_1	2	8	PF00069	0.687
MOD_GlcNHglycan	1	4	PF01048	0.503
MOD_GlcNHglycan	23	26	PF01048	0.398
MOD_GlcNHglycan	57	60	PF01048	0.432
MOD_GSK3_1	12	19	PF00069	0.654
MOD_GSK3_1	35	42	PF00069	0.485
MOD_GSK3_1	51	58	PF00069	0.449
MOD_N-GLC_1	83	88	PF02516	0.449
MOD_NEK2_1	43	48	PF00069	0.467
MOD_NEK2_2	39	44	PF00069	0.233
MOD_NEK2_2	63	68	PF00069	0.388
MOD_PIKK_1	83	89	PF00454	0.725
MOD_PKB_1	81	89	PF00069	0.722
MOD_Plk_1	83	89	PF00069	0.686
MOD_Plk_4	35	41	PF00069	0.466
MOD_Plk_4	63	69	PF00069	0.395
MOD_Plk_4	71	77	PF00069	0.377
TRG_ENDOCYTIC_2	40	43	PF00928	0.344
TRG_ER_diArg_1	81	83	PF00400	0.638


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBG0	Leptomonas seymouri	65%	93%
A0A1X0NRX6	Trypanosomatidae	37%	96%
A0A3R7LD90	Trypanosoma rangeli	33%	96%
A0A3S7X638	Leishmania donovani	79%	97%
A4I8H9	Leishmania infantum	79%	97%
E9B3D9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
Q4Q4R3	Leishmania major	73%	100%
V5DMF6	Trypanosoma cruzi	33%	96%