TROVE domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

TROVE domain containing protein, putative

Species:

Leishmania braziliensis

UniProt:

E9AIS2_LEIBR

TriTrypDb:

LbrM.26.1130 , LBRM2903_260016300

Length:

4193

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AIS2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	7
GO:0003723	RNA binding	4	7
GO:0005488	binding	1	7
GO:0097159	organic cyclic compound binding	2	7
GO:1901363	heterocyclic compound binding	2	7

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1131	1135	PF00656	0.447
CLV_C14_Caspase3-7	1189	1193	PF00656	0.538
CLV_C14_Caspase3-7	1561	1565	PF00656	0.581
CLV_C14_Caspase3-7	1592	1596	PF00656	0.474
CLV_C14_Caspase3-7	171	175	PF00656	0.438
CLV_C14_Caspase3-7	2134	2138	PF00656	0.520
CLV_C14_Caspase3-7	311	315	PF00656	0.507
CLV_C14_Caspase3-7	317	321	PF00656	0.551
CLV_C14_Caspase3-7	53	57	PF00656	0.402
CLV_C14_Caspase3-7	706	710	PF00656	0.471

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I249	Leptomonas seymouri	45%	96%
A0A3S5H7G1	Leishmania donovani	68%	100%
A4I240	Leishmania infantum	68%	100%
E9AY90	Leishmania mexicana (strain MHOM/GT/2001/U1103)	69%	100%
Q4Q983	Leishmania major	68%	98%

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