LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
E9AIR4_LEIBR
TriTrypDb:
LbrM.25.0301 , LBRM2903_250008400
Length:
90

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AIR4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AIR4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 46 48 PF00675 0.695
CLV_PCSK_KEX2_1 46 48 PF00082 0.695
CLV_PCSK_SKI1_1 47 51 PF00082 0.685
CLV_PCSK_SKI1_1 67 71 PF00082 0.287
CLV_PCSK_SKI1_1 81 85 PF00082 0.338
DEG_APCC_DBOX_1 45 53 PF00400 0.522
DOC_MAPK_gen_1 46 53 PF00069 0.492
DOC_MAPK_MEF2A_6 34 41 PF00069 0.542
DOC_MAPK_MEF2A_6 46 55 PF00069 0.422
DOC_PP4_FxxP_1 83 86 PF00568 0.591
DOC_USP7_MATH_1 86 90 PF00917 0.622
DOC_WW_Pin1_4 17 22 PF00397 0.550
DOC_WW_Pin1_4 39 44 PF00397 0.445
LIG_14-3-3_CterR_2 85 90 PF00244 0.618
LIG_BIR_II_1 1 5 PF00653 0.634
LIG_BRCT_BRCA1_1 62 66 PF00533 0.332
LIG_CtBP_PxDLS_1 38 42 PF00389 0.419
LIG_FHA_1 21 27 PF00498 0.443
LIG_FHA_1 7 13 PF00498 0.521
LIG_FHA_2 40 46 PF00498 0.543
LIG_LIR_Apic_2 82 86 PF02991 0.588
LIG_WRC_WIRS_1 80 85 PF05994 0.576
MOD_CDK_SPxxK_3 39 46 PF00069 0.549
MOD_CK2_1 39 45 PF00069 0.500
MOD_GlcNHglycan 1 4 PF01048 0.718
MOD_GlcNHglycan 30 34 PF01048 0.740
MOD_GlcNHglycan 74 77 PF01048 0.529
MOD_N-GLC_1 39 44 PF02516 0.579
MOD_Plk_4 61 67 PF00069 0.300
MOD_ProDKin_1 17 23 PF00069 0.551
MOD_ProDKin_1 39 45 PF00069 0.441
TRG_DiLeu_BaEn_1 45 50 PF01217 0.525
TRG_ENDOCYTIC_2 80 83 PF00928 0.634

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8ID69 Leishmania donovani 62% 100%
A4I173 Leishmania infantum 61% 100%
E9AXA7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 62% 100%
Q4QA65 Leishmania major 60% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS