YTH domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

E9AIP6_LEIBR

TriTrypDb:

LbrM.20.6130 , LBRM2903_200063700

Length:

727

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AIP6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AIP6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	325	329	PF00656	0.831
CLV_PCSK_SKI1_1	482	486	PF00082	0.827
DEG_SPOP_SBC_1	344	348	PF00917	0.869
DOC_CDC14_PxL_1	107	115	PF14671	0.847
DOC_CDC14_PxL_1	164	172	PF14671	0.875
DOC_CKS1_1	666	671	PF01111	0.844
DOC_CYCLIN_yCln2_LP_2	538	544	PF00134	0.873
DOC_CYCLIN_yCln2_LP_2	606	612	PF00134	0.772
DOC_PP2B_LxvP_1	530	533	PF13499	0.861
DOC_PP2B_LxvP_1	558	561	PF13499	0.854
DOC_PP4_FxxP_1	112	115	PF00568	0.847
DOC_USP7_MATH_1	209	213	PF00917	0.880
DOC_USP7_MATH_1	235	239	PF00917	0.831
DOC_USP7_MATH_1	268	272	PF00917	0.861
DOC_USP7_MATH_1	293	297	PF00917	0.840
DOC_USP7_MATH_1	332	336	PF00917	0.845
DOC_USP7_MATH_1	396	400	PF00917	0.885
DOC_USP7_MATH_1	409	413	PF00917	0.658
DOC_USP7_MATH_1	502	506	PF00917	0.843
DOC_USP7_MATH_1	514	518	PF00917	0.633
DOC_USP7_MATH_1	520	524	PF00917	0.545
DOC_USP7_MATH_1	610	614	PF00917	0.800
DOC_USP7_MATH_1	681	685	PF00917	0.820
DOC_USP7_MATH_1	712	716	PF00917	0.837
DOC_USP7_MATH_2	127	133	PF00917	0.873
DOC_USP7_MATH_2	143	149	PF00917	0.580
DOC_WW_Pin1_4	133	138	PF00397	0.862
DOC_WW_Pin1_4	184	189	PF00397	0.847
DOC_WW_Pin1_4	238	243	PF00397	0.820
DOC_WW_Pin1_4	272	277	PF00397	0.850
DOC_WW_Pin1_4	283	288	PF00397	0.658
DOC_WW_Pin1_4	328	333	PF00397	0.836
DOC_WW_Pin1_4	345	350	PF00397	0.570
DOC_WW_Pin1_4	383	388	PF00397	0.861
DOC_WW_Pin1_4	417	422	PF00397	0.869
DOC_WW_Pin1_4	42	47	PF00397	0.863
DOC_WW_Pin1_4	561	566	PF00397	0.871
DOC_WW_Pin1_4	579	584	PF00397	0.575
DOC_WW_Pin1_4	587	592	PF00397	0.713
DOC_WW_Pin1_4	6	11	PF00397	0.847
DOC_WW_Pin1_4	640	645	PF00397	0.871
DOC_WW_Pin1_4	665	670	PF00397	0.846
DOC_WW_Pin1_4	694	699	PF00397	0.833
DOC_WW_Pin1_4	707	712	PF00397	0.608
LIG_14-3-3_CanoR_1	277	285	PF00244	0.861
LIG_14-3-3_CanoR_1	40	46	PF00244	0.863
LIG_BRCT_BRCA1_1	715	719	PF00533	0.839
LIG_CtBP_PxDLS_1	143	147	PF00389	0.859
LIG_eIF4E_1	713	719	PF01652	0.841
LIG_FHA_1	1	7	PF00498	0.841
LIG_FHA_1	329	335	PF00498	0.837
LIG_FHA_1	352	358	PF00498	0.868
LIG_FHA_1	421	427	PF00498	0.860
LIG_FHA_1	520	526	PF00498	0.859
LIG_FHA_1	533	539	PF00498	0.639
LIG_FHA_1	666	672	PF00498	0.842
LIG_FHA_1	89	95	PF00498	0.853
LIG_FHA_2	11	17	PF00498	0.841
LIG_FHA_2	412	418	PF00498	0.883
LIG_FHA_2	462	468	PF00498	0.857
LIG_FHA_2	532	538	PF00498	0.866
LIG_LIR_Apic_2	148	153	PF02991	0.863
LIG_LYPXL_yS_3	636	639	PF13949	0.867
LIG_MYND_1	111	115	PF01753	0.844
LIG_MYND_1	196	200	PF01753	0.854
LIG_Pex14_1	687	691	PF04695	0.821
LIG_Pex14_2	705	709	PF04695	0.842
LIG_SH2_CRK	107	111	PF00017	0.847
LIG_SH2_CRK	150	154	PF00017	0.863
LIG_SH2_CRK	245	249	PF00017	0.841
LIG_SH2_CRK	691	695	PF00017	0.833
LIG_SH2_GRB2like	90	93	PF00017	0.851
LIG_SH2_NCK_1	107	111	PF00017	0.847
LIG_SH2_NCK_1	150	154	PF00017	0.863
LIG_SH2_NCK_1	236	240	PF00017	0.829
LIG_SH2_NCK_1	245	249	PF00017	0.684
LIG_SH2_NCK_1	597	601	PF00017	0.791
LIG_SH2_SRC	107	110	PF00017	0.851
LIG_SH2_STAP1	90	94	PF00017	0.853
LIG_SH2_STAT3	556	559	PF00017	0.852
LIG_SH2_STAT5	556	559	PF00017	0.852
LIG_SH2_STAT5	597	600	PF00017	0.784
LIG_SH2_STAT5	90	93	PF00017	0.851
LIG_SH3_1	540	546	PF00018	0.869
LIG_SH3_3	203	209	PF00018	0.870
LIG_SH3_3	381	387	PF00018	0.857
LIG_SH3_3	483	489	PF00018	0.828
LIG_SH3_3	540	546	PF00018	0.869
LIG_SH3_3	573	579	PF00018	0.902
LIG_SH3_3	588	594	PF00018	0.579
LIG_SH3_3	639	645	PF00018	0.871
LIG_SH3_3	654	660	PF00018	0.617
LIG_TYR_ITIM	634	639	PF00017	0.863
MOD_CDC14_SPxK_1	286	289	PF00782	0.842
MOD_CDK_SPK_2	272	277	PF00069	0.850
MOD_CDK_SPK_2	383	388	PF00069	0.861
MOD_CDK_SPK_2	417	422	PF00069	0.869
MOD_CDK_SPxK_1	283	289	PF00069	0.852
MOD_CK1_1	120	126	PF00069	0.861
MOD_CK1_1	212	218	PF00069	0.892
MOD_CK1_1	238	244	PF00069	0.824
MOD_CK1_1	256	262	PF00069	0.526
MOD_CK1_1	269	275	PF00069	0.629
MOD_CK1_1	335	341	PF00069	0.864
MOD_CK1_1	343	349	PF00069	0.728
MOD_CK1_1	39	45	PF00069	0.867
MOD_CK1_1	460	466	PF00069	0.861
MOD_CK1_1	473	479	PF00069	0.608
MOD_CK1_1	496	502	PF00069	0.848
MOD_CK1_1	523	529	PF00069	0.858
MOD_CK1_1	697	703	PF00069	0.825
MOD_CK1_1	704	710	PF00069	0.716
MOD_CK2_1	10	16	PF00069	0.835
MOD_CK2_1	411	417	PF00069	0.887
MOD_CK2_1	44	50	PF00069	0.863
MOD_CK2_1	461	467	PF00069	0.860
MOD_CK2_1	531	537	PF00069	0.863
MOD_GlcNHglycan	133	136	PF01048	0.870
MOD_GlcNHglycan	139	142	PF01048	0.740
MOD_GlcNHglycan	147	150	PF01048	0.624
MOD_GlcNHglycan	170	173	PF01048	0.872
MOD_GlcNHglycan	214	217	PF01048	0.895
MOD_GlcNHglycan	231	234	PF01048	0.535
MOD_GlcNHglycan	237	240	PF01048	0.722
MOD_GlcNHglycan	268	271	PF01048	0.862
MOD_GlcNHglycan	29	32	PF01048	0.861
MOD_GlcNHglycan	354	357	PF01048	0.869
MOD_GlcNHglycan	390	393	PF01048	0.874
MOD_GlcNHglycan	398	401	PF01048	0.745
MOD_GlcNHglycan	41	44	PF01048	0.657
MOD_GlcNHglycan	495	498	PF01048	0.857
MOD_GlcNHglycan	612	615	PF01048	0.805
MOD_GlcNHglycan	706	709	PF01048	0.841
MOD_GlcNHglycan	98	101	PF01048	0.852
MOD_GSK3_1	129	136	PF00069	0.872
MOD_GSK3_1	179	186	PF00069	0.869
MOD_GSK3_1	194	201	PF00069	0.591
MOD_GSK3_1	266	273	PF00069	0.862
MOD_GSK3_1	291	298	PF00069	0.842
MOD_GSK3_1	328	335	PF00069	0.838
MOD_GSK3_1	340	347	PF00069	0.663
MOD_GSK3_1	35	42	PF00069	0.866
MOD_GSK3_1	416	423	PF00069	0.871
MOD_GSK3_1	44	51	PF00069	0.706
MOD_GSK3_1	457	464	PF00069	0.861
MOD_GSK3_1	519	526	PF00069	0.857
MOD_GSK3_1	6	13	PF00069	0.844
MOD_GSK3_1	697	704	PF00069	0.825
MOD_N-GLC_1	168	173	PF02516	0.873
MOD_N-GLC_1	177	182	PF02516	0.714
MOD_N-GLC_1	388	393	PF02516	0.875
MOD_N-GLC_1	55	60	PF02516	0.865
MOD_N-GLC_1	713	718	PF02516	0.841
MOD_N-GLC_2	34	36	PF02516	0.868
MOD_NEK2_1	1	6	PF00069	0.838
MOD_NEK2_1	163	168	PF00069	0.875
MOD_NEK2_1	170	175	PF00069	0.747
MOD_NEK2_1	214	219	PF00069	0.892
MOD_NEK2_1	299	304	PF00069	0.841
MOD_NEK2_1	352	357	PF00069	0.870
MOD_NEK2_1	425	430	PF00069	0.851
MOD_NEK2_1	470	475	PF00069	0.851
MOD_NEK2_1	493	498	PF00069	0.855
MOD_NEK2_1	55	60	PF00069	0.865
MOD_NEK2_1	595	600	PF00069	0.789
MOD_PIKK_1	152	158	PF00454	0.860
MOD_PIKK_1	215	221	PF00454	0.887
MOD_PIKK_1	293	299	PF00454	0.840
MOD_PIKK_1	473	479	PF00454	0.835
MOD_PIKK_1	571	577	PF00454	0.904
MOD_PIKK_1	659	665	PF00454	0.864
MOD_PK_1	447	453	PF00069	0.854
MOD_PKA_1	447	453	PF00069	0.854
MOD_PKA_2	276	282	PF00069	0.854
MOD_PKA_2	39	45	PF00069	0.867
MOD_PKA_2	460	466	PF00069	0.861
MOD_PKA_2	65	71	PF00069	0.855
MOD_Plk_1	48	54	PF00069	0.859
MOD_Plk_1	502	508	PF00069	0.844
MOD_Plk_1	721	727	PF00069	0.849
MOD_Plk_4	295	301	PF00069	0.841
MOD_Plk_4	322	328	PF00069	0.832
MOD_Plk_4	502	508	PF00069	0.844
MOD_Plk_4	520	526	PF00069	0.544
MOD_ProDKin_1	133	139	PF00069	0.860
MOD_ProDKin_1	184	190	PF00069	0.848
MOD_ProDKin_1	238	244	PF00069	0.824
MOD_ProDKin_1	272	278	PF00069	0.851
MOD_ProDKin_1	283	289	PF00069	0.659
MOD_ProDKin_1	328	334	PF00069	0.837
MOD_ProDKin_1	345	351	PF00069	0.571
MOD_ProDKin_1	383	389	PF00069	0.863
MOD_ProDKin_1	417	423	PF00069	0.869
MOD_ProDKin_1	42	48	PF00069	0.862
MOD_ProDKin_1	561	567	PF00069	0.875
MOD_ProDKin_1	579	585	PF00069	0.576
MOD_ProDKin_1	587	593	PF00069	0.709
MOD_ProDKin_1	6	12	PF00069	0.847
MOD_ProDKin_1	640	646	PF00069	0.872
MOD_ProDKin_1	665	671	PF00069	0.845
MOD_ProDKin_1	694	700	PF00069	0.832
MOD_ProDKin_1	707	713	PF00069	0.609
MOD_SUMO_rev_2	325	332	PF00179	0.831
MOD_SUMO_rev_2	439	449	PF00179	0.853
TRG_DiLeu_BaEn_1	50	55	PF01217	0.861
TRG_DiLeu_BaLyEn_6	601	606	PF01217	0.765
TRG_ENDOCYTIC_2	107	110	PF00928	0.553
TRG_ENDOCYTIC_2	245	248	PF00928	0.847
TRG_ENDOCYTIC_2	481	484	PF00928	0.827
TRG_ENDOCYTIC_2	596	599	PF00928	0.792
TRG_ENDOCYTIC_2	636	639	PF00928	0.867
TRG_ENDOCYTIC_2	691	694	PF00928	0.834
TRG_ENDOCYTIC_2	90	93	PF00928	0.851