CLASP_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

E9AIP3_LEIBR

TriTrypDb:

LbrM.20.6100 , LBRM2903_200066600

Length:

880

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AIP3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AIP3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	119	123	PF00656	0.696
CLV_C14_Caspase3-7	291	295	PF00656	0.576
CLV_C14_Caspase3-7	296	300	PF00656	0.588
CLV_C14_Caspase3-7	306	310	PF00656	0.624
CLV_C14_Caspase3-7	432	436	PF00656	0.643
CLV_C14_Caspase3-7	49	53	PF00656	0.659
CLV_NRD_NRD_1	131	133	PF00675	0.726
CLV_NRD_NRD_1	156	158	PF00675	0.698
CLV_NRD_NRD_1	177	179	PF00675	0.715
CLV_NRD_NRD_1	359	361	PF00675	0.698
CLV_NRD_NRD_1	538	540	PF00675	0.714
CLV_NRD_NRD_1	544	546	PF00675	0.660
CLV_NRD_NRD_1	622	624	PF00675	0.842
CLV_NRD_NRD_1	673	675	PF00675	0.705
CLV_NRD_NRD_1	773	775	PF00675	0.668
CLV_NRD_NRD_1	82	84	PF00675	0.729
CLV_NRD_NRD_1	830	832	PF00675	0.785
CLV_PCSK_FUR_1	771	775	PF00082	0.672
CLV_PCSK_KEX2_1	131	133	PF00082	0.748
CLV_PCSK_KEX2_1	313	315	PF00082	0.726
CLV_PCSK_KEX2_1	359	361	PF00082	0.761
CLV_PCSK_KEX2_1	420	422	PF00082	0.656
CLV_PCSK_KEX2_1	544	546	PF00082	0.571
CLV_PCSK_KEX2_1	622	624	PF00082	0.756
CLV_PCSK_KEX2_1	673	675	PF00082	0.598
CLV_PCSK_KEX2_1	773	775	PF00082	0.815
CLV_PCSK_KEX2_1	830	832	PF00082	0.662
CLV_PCSK_PC1ET2_1	313	315	PF00082	0.726
CLV_PCSK_PC1ET2_1	420	422	PF00082	0.582
CLV_PCSK_PC7_1	769	775	PF00082	0.675
CLV_PCSK_SKI1_1	179	183	PF00082	0.572
CLV_PCSK_SKI1_1	285	289	PF00082	0.612
CLV_PCSK_SKI1_1	332	336	PF00082	0.778
CLV_PCSK_SKI1_1	539	543	PF00082	0.709
CLV_PCSK_SKI1_1	593	597	PF00082	0.712
CLV_PCSK_SKI1_1	674	678	PF00082	0.614
CLV_PCSK_SKI1_1	795	799	PF00082	0.588
DEG_Nend_Nbox_1	1	3	PF02207	0.711
DEG_SCF_FBW7_1	465	472	PF00400	0.538
DEG_SCF_FBW7_1	614	620	PF00400	0.720
DEG_SPOP_SBC_1	103	107	PF00917	0.567
DEG_SPOP_SBC_1	201	205	PF00917	0.640
DEG_SPOP_SBC_1	44	48	PF00917	0.577
DEG_SPOP_SBC_1	471	475	PF00917	0.544
DOC_CKS1_1	451	456	PF01111	0.689
DOC_CKS1_1	534	539	PF01111	0.557
DOC_CKS1_1	614	619	PF01111	0.722
DOC_CKS1_1	775	780	PF01111	0.659
DOC_PP2B_LxvP_1	2	5	PF13499	0.708
DOC_PP2B_LxvP_1	231	234	PF13499	0.698
DOC_USP7_MATH_1	101	105	PF00917	0.730
DOC_USP7_MATH_1	136	140	PF00917	0.676
DOC_USP7_MATH_1	196	200	PF00917	0.658
DOC_USP7_MATH_1	201	205	PF00917	0.623
DOC_USP7_MATH_1	214	218	PF00917	0.532
DOC_USP7_MATH_1	234	238	PF00917	0.703
DOC_USP7_MATH_1	240	244	PF00917	0.655
DOC_USP7_MATH_1	283	287	PF00917	0.716
DOC_USP7_MATH_1	345	349	PF00917	0.653
DOC_USP7_MATH_1	469	473	PF00917	0.538
DOC_USP7_MATH_1	520	524	PF00917	0.716
DOC_USP7_MATH_1	559	563	PF00917	0.666
DOC_USP7_MATH_1	571	575	PF00917	0.621
DOC_USP7_MATH_1	580	584	PF00917	0.640
DOC_USP7_MATH_1	595	599	PF00917	0.572
DOC_WW_Pin1_4	106	111	PF00397	0.718
DOC_WW_Pin1_4	262	267	PF00397	0.723
DOC_WW_Pin1_4	445	450	PF00397	0.724
DOC_WW_Pin1_4	465	470	PF00397	0.491
DOC_WW_Pin1_4	482	487	PF00397	0.516
DOC_WW_Pin1_4	504	509	PF00397	0.693
DOC_WW_Pin1_4	511	516	PF00397	0.594
DOC_WW_Pin1_4	526	531	PF00397	0.635
DOC_WW_Pin1_4	533	538	PF00397	0.654
DOC_WW_Pin1_4	561	566	PF00397	0.582
DOC_WW_Pin1_4	569	574	PF00397	0.577
DOC_WW_Pin1_4	585	590	PF00397	0.673
DOC_WW_Pin1_4	613	618	PF00397	0.752
DOC_WW_Pin1_4	653	658	PF00397	0.748
DOC_WW_Pin1_4	693	698	PF00397	0.633
DOC_WW_Pin1_4	70	75	PF00397	0.715
DOC_WW_Pin1_4	774	779	PF00397	0.664
DOC_WW_Pin1_4	803	808	PF00397	0.619
DOC_WW_Pin1_4	89	94	PF00397	0.569
LIG_14-3-3_CanoR_1	178	186	PF00244	0.714
LIG_14-3-3_CanoR_1	190	196	PF00244	0.702
LIG_14-3-3_CanoR_1	285	290	PF00244	0.575
LIG_14-3-3_CanoR_1	364	368	PF00244	0.582
LIG_14-3-3_CanoR_1	369	373	PF00244	0.562
LIG_14-3-3_CanoR_1	653	657	PF00244	0.568
LIG_14-3-3_CanoR_1	776	782	PF00244	0.654
LIG_14-3-3_CanoR_1	87	93	PF00244	0.608
LIG_14-3-3_CterR_2	878	880	PF00244	0.583
LIG_APCC_ABBAyCdc20_2	157	163	PF00400	0.690
LIG_BIR_III_2	183	187	PF00653	0.564
LIG_BRCT_BRCA1_1	472	476	PF00533	0.637
LIG_DCNL_PONY_1	1	4	PF03556	0.710
LIG_FHA_1	210	216	PF00498	0.560
LIG_FHA_1	282	288	PF00498	0.569
LIG_FHA_1	369	375	PF00498	0.574
LIG_FHA_1	466	472	PF00498	0.684
LIG_FHA_1	529	535	PF00498	0.547
LIG_FHA_1	614	620	PF00498	0.720
LIG_FHA_1	685	691	PF00498	0.507
LIG_FHA_2	47	53	PF00498	0.662
LIG_FHA_2	653	659	PF00498	0.622
LIG_Integrin_RGD_1	853	855	PF01839	0.590
LIG_LIR_Apic_2	243	249	PF02991	0.571
LIG_LIR_Gen_1	473	484	PF02991	0.688
LIG_LIR_Gen_1	678	688	PF02991	0.656
LIG_LIR_Nem_3	20	24	PF02991	0.691
LIG_LIR_Nem_3	473	479	PF02991	0.697
LIG_LIR_Nem_3	56	61	PF02991	0.553
LIG_LIR_Nem_3	678	683	PF02991	0.640
LIG_MYND_1	262	266	PF01753	0.720
LIG_NBox_RRM_1	794	804	PF00076	0.594
LIG_Pex14_1	459	463	PF04695	0.695
LIG_SH2_CRK	24	28	PF00017	0.679
LIG_SH2_CRK	246	250	PF00017	0.576
LIG_SH2_CRK	259	263	PF00017	0.722
LIG_SH2_CRK	61	65	PF00017	0.708
LIG_SH2_GRB2like	325	328	PF00017	0.717
LIG_SH2_NCK_1	463	467	PF00017	0.688
LIG_SH2_SRC	19	22	PF00017	0.699
LIG_SH3_1	483	489	PF00018	0.534
LIG_SH3_1	79	85	PF00018	0.732
LIG_SH3_2	82	87	PF14604	0.731
LIG_SH3_3	163	169	PF00018	0.686
LIG_SH3_3	260	266	PF00018	0.720
LIG_SH3_3	38	44	PF00018	0.581
LIG_SH3_3	416	422	PF00018	0.582
LIG_SH3_3	476	482	PF00018	0.686
LIG_SH3_3	483	489	PF00018	0.614
LIG_SH3_3	524	530	PF00018	0.590
LIG_SH3_3	531	537	PF00018	0.604
LIG_SH3_3	583	589	PF00018	0.568
LIG_SH3_3	651	657	PF00018	0.582
LIG_SH3_3	757	763	PF00018	0.734
LIG_SH3_3	79	85	PF00018	0.709
LIG_SH3_3	801	807	PF00018	0.629
LIG_SUMO_SIM_par_1	684	689	PF11976	0.632
LIG_TRAF2_2	850	855	PF00917	0.586
LIG_UBA3_1	1	8	PF00899	0.711
LIG_WW_3	758	762	PF00397	0.635
MOD_CDC14_SPxK_1	485	488	PF00782	0.531
MOD_CDK_SPK_2	106	111	PF00069	0.568
MOD_CDK_SPK_2	450	455	PF00069	0.699
MOD_CDK_SPK_2	774	779	PF00069	0.664
MOD_CDK_SPxK_1	482	488	PF00069	0.532
MOD_CDK_SPxK_1	533	539	PF00069	0.703
MOD_CDK_SPxK_1	569	575	PF00069	0.592
MOD_CDK_SPxxK_3	106	113	PF00069	0.572
MOD_CDK_SPxxK_3	533	540	PF00069	0.704
MOD_CDK_SPxxK_3	693	700	PF00069	0.571
MOD_CK1_1	104	110	PF00069	0.566
MOD_CK1_1	148	154	PF00069	0.642
MOD_CK1_1	341	347	PF00069	0.578
MOD_CK1_1	368	374	PF00069	0.694
MOD_CK1_1	412	418	PF00069	0.733
MOD_CK1_1	429	435	PF00069	0.631
MOD_CK1_1	46	52	PF00069	0.605
MOD_CK1_1	472	478	PF00069	0.547
MOD_CK1_1	503	509	PF00069	0.588
MOD_CK1_1	550	556	PF00069	0.576
MOD_CK1_1	564	570	PF00069	0.582
MOD_CK1_1	613	619	PF00069	0.580
MOD_CK1_1	646	652	PF00069	0.611
MOD_CK2_1	511	517	PF00069	0.592
MOD_CK2_1	526	532	PF00069	0.606
MOD_CK2_1	637	643	PF00069	0.576
MOD_Cter_Amidation	129	132	PF01082	0.584
MOD_DYRK1A_RPxSP_1	653	657	PF00069	0.568
MOD_GlcNHglycan	128	131	PF01048	0.582
MOD_GlcNHglycan	138	141	PF01048	0.711
MOD_GlcNHglycan	193	196	PF01048	0.754
MOD_GlcNHglycan	216	219	PF01048	0.656
MOD_GlcNHglycan	223	226	PF01048	0.690
MOD_GlcNHglycan	281	284	PF01048	0.721
MOD_GlcNHglycan	305	308	PF01048	0.567
MOD_GlcNHglycan	422	425	PF01048	0.774
MOD_GlcNHglycan	428	431	PF01048	0.756
MOD_GlcNHglycan	476	479	PF01048	0.555
MOD_GlcNHglycan	502	505	PF01048	0.691
MOD_GlcNHglycan	522	525	PF01048	0.658
MOD_GlcNHglycan	552	555	PF01048	0.575
MOD_GlcNHglycan	582	585	PF01048	0.718
MOD_GlcNHglycan	597	600	PF01048	0.558
MOD_GlcNHglycan	648	651	PF01048	0.583
MOD_GlcNHglycan	99	102	PF01048	0.729
MOD_GSK3_1	141	148	PF00069	0.706
MOD_GSK3_1	152	159	PF00069	0.590
MOD_GSK3_1	191	198	PF00069	0.754
MOD_GSK3_1	234	241	PF00069	0.663
MOD_GSK3_1	262	269	PF00069	0.599
MOD_GSK3_1	279	286	PF00069	0.684
MOD_GSK3_1	289	296	PF00069	0.606
MOD_GSK3_1	299	306	PF00069	0.513
MOD_GSK3_1	332	339	PF00069	0.705
MOD_GSK3_1	341	348	PF00069	0.656
MOD_GSK3_1	368	375	PF00069	0.636
MOD_GSK3_1	405	412	PF00069	0.732
MOD_GSK3_1	42	49	PF00069	0.668
MOD_GSK3_1	440	447	PF00069	0.712
MOD_GSK3_1	465	472	PF00069	0.631
MOD_GSK3_1	500	507	PF00069	0.678
MOD_GSK3_1	526	533	PF00069	0.687
MOD_GSK3_1	557	564	PF00069	0.588
MOD_GSK3_1	567	574	PF00069	0.649
MOD_GSK3_1	575	582	PF00069	0.629
MOD_GSK3_1	585	592	PF00069	0.556
MOD_GSK3_1	609	616	PF00069	0.691
MOD_GSK3_1	645	652	PF00069	0.598
MOD_GSK3_1	663	670	PF00069	0.502
MOD_GSK3_1	85	92	PF00069	0.646
MOD_GSK3_1	97	104	PF00069	0.695
MOD_N-GLC_1	445	450	PF02516	0.798
MOD_N-GLC_1	550	555	PF02516	0.719
MOD_N-GLC_1	693	698	PF02516	0.575
MOD_N-GLC_1	88	93	PF02516	0.721
MOD_NEK2_1	221	226	PF00069	0.558
MOD_NEK2_1	34	39	PF00069	0.724
MOD_NEK2_1	494	499	PF00069	0.548
MOD_NEK2_1	591	596	PF00069	0.634
MOD_NEK2_1	686	691	PF00069	0.715
MOD_PIKK_1	557	563	PF00454	0.578
MOD_PIKK_1	695	701	PF00454	0.560
MOD_PKA_1	179	185	PF00069	0.719
MOD_PKA_1	420	426	PF00069	0.581
MOD_PKA_1	83	89	PF00069	0.734
MOD_PKA_2	152	158	PF00069	0.651
MOD_PKA_2	363	369	PF00069	0.792
MOD_PKA_2	405	411	PF00069	0.597
MOD_PKA_2	420	426	PF00069	0.785
MOD_PKA_2	652	658	PF00069	0.568
MOD_PKA_2	701	707	PF00069	0.492
MOD_PKA_2	709	715	PF00069	0.503
MOD_PKA_2	97	103	PF00069	0.586
MOD_Plk_1	145	151	PF00069	0.707
MOD_Plk_1	196	202	PF00069	0.551
MOD_Plk_1	293	299	PF00069	0.557
MOD_Plk_2-3	808	814	PF00069	0.590
MOD_Plk_4	530	536	PF00069	0.547
MOD_ProDKin_1	106	112	PF00069	0.719
MOD_ProDKin_1	262	268	PF00069	0.723
MOD_ProDKin_1	445	451	PF00069	0.723
MOD_ProDKin_1	465	471	PF00069	0.493
MOD_ProDKin_1	482	488	PF00069	0.516
MOD_ProDKin_1	504	510	PF00069	0.693
MOD_ProDKin_1	511	517	PF00069	0.594
MOD_ProDKin_1	526	532	PF00069	0.635
MOD_ProDKin_1	533	539	PF00069	0.657
MOD_ProDKin_1	561	567	PF00069	0.586
MOD_ProDKin_1	569	575	PF00069	0.579
MOD_ProDKin_1	585	591	PF00069	0.674
MOD_ProDKin_1	613	619	PF00069	0.752
MOD_ProDKin_1	653	659	PF00069	0.747
MOD_ProDKin_1	693	699	PF00069	0.631
MOD_ProDKin_1	70	76	PF00069	0.714
MOD_ProDKin_1	774	780	PF00069	0.658
MOD_ProDKin_1	803	809	PF00069	0.616
MOD_ProDKin_1	89	95	PF00069	0.572
MOD_SUMO_for_1	354	357	PF00179	0.704
MOD_SUMO_rev_2	384	391	PF00179	0.563
MOD_SUMO_rev_2	605	611	PF00179	0.573
TRG_DiLeu_BaEn_2	815	821	PF01217	0.580
TRG_DiLeu_BaEn_4	356	362	PF01217	0.711
TRG_ENDOCYTIC_2	24	27	PF00928	0.678
TRG_ENDOCYTIC_2	61	64	PF00928	0.707
TRG_ER_diArg_1	188	191	PF00400	0.564
TRG_ER_diArg_1	359	361	PF00400	0.718
TRG_ER_diArg_1	622	624	PF00400	0.754
TRG_ER_diArg_1	747	750	PF00400	0.653
TRG_ER_diArg_1	768	771	PF00400	0.679
TRG_ER_diArg_1	772	774	PF00400	0.488
TRG_ER_diArg_1	830	833	PF00400	0.756
TRG_NLS_MonoExtC_3	177	183	PF00514	0.717

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H787	Leishmania donovani	71%	98%
A4HYU5	Leishmania infantum	71%	98%
E9AUP2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	70%	99%
Q4QCU2	Leishmania major	71%	99%