Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

E9AIN7_LEIBR

TriTrypDb:

LbrM.20.6040 , LBRM2903_200076000

Length:

213

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AIN7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AIN7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	201	203	PF00675	0.550
CLV_PCSK_FUR_1	199	203	PF00082	0.549
CLV_PCSK_KEX2_1	199	201	PF00082	0.545
CLV_PCSK_KEX2_1	204	206	PF00082	0.562
CLV_PCSK_PC1ET2_1	204	206	PF00082	0.593
CLV_PCSK_PC7_1	200	206	PF00082	0.559
CLV_PCSK_SKI1_1	174	178	PF00082	0.568
DEG_Nend_UBRbox_2	1	3	PF02207	0.689
DOC_MAPK_MEF2A_6	94	102	PF00069	0.411
DOC_PP1_RVXF_1	92	98	PF00149	0.492
DOC_PP2B_LxvP_1	80	83	PF13499	0.516
DOC_PP4_FxxP_1	143	146	PF00568	0.618
LIG_14-3-3_CanoR_1	94	98	PF00244	0.599
LIG_BRCT_BRCA1_1	127	131	PF00533	0.485
LIG_FHA_1	13	19	PF00498	0.607
LIG_FHA_1	142	148	PF00498	0.616
LIG_FHA_1	176	182	PF00498	0.534
LIG_Integrin_RGD_1	160	162	PF01839	0.569
LIG_LIR_Gen_1	96	105	PF02991	0.549
LIG_LIR_Nem_3	96	100	PF02991	0.553
LIG_MAD2	16	24	PF02301	0.527
LIG_PTAP_UEV_1	20	25	PF05743	0.514
LIG_RPA_C_Fungi	188	200	PF08784	0.432
LIG_SH2_CRK	119	123	PF00017	0.478
LIG_SH2_STAT5	121	124	PF00017	0.575
LIG_SH3_3	14	20	PF00018	0.528
LIG_SUMO_SIM_par_1	40	46	PF11976	0.503
LIG_TRAF2_1	110	113	PF00917	0.553
LIG_TRAF2_1	72	75	PF00917	0.480
LIG_TYR_ITIM	117	122	PF00017	0.433
MOD_CK1_1	151	157	PF00069	0.454
MOD_CK1_1	170	176	PF00069	0.523
MOD_CK2_1	69	75	PF00069	0.480
MOD_Cter_Amidation	5	8	PF01082	0.528
MOD_GlcNHglycan	136	139	PF01048	0.510
MOD_GlcNHglycan	21	24	PF01048	0.661
MOD_GlcNHglycan	31	34	PF01048	0.603
MOD_GlcNHglycan	4	7	PF01048	0.569
MOD_GlcNHglycan	71	74	PF01048	0.539
MOD_GlcNHglycan	80	83	PF01048	0.584
MOD_GSK3_1	52	59	PF00069	0.482
MOD_NEK2_1	189	194	PF00069	0.577
MOD_PKA_1	200	206	PF00069	0.615
MOD_PKA_2	189	195	PF00069	0.640
MOD_PKA_2	2	8	PF00069	0.541
MOD_PKA_2	200	206	PF00069	0.503
MOD_PKA_2	93	99	PF00069	0.557
TRG_DiLeu_BaEn_1	164	169	PF01217	0.633
TRG_DiLeu_BaEn_4	112	118	PF01217	0.430
TRG_ENDOCYTIC_2	119	122	PF00928	0.528
TRG_ER_diArg_1	152	155	PF00400	0.726
TRG_ER_diArg_1	198	201	PF00400	0.607

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILD1	Leptomonas seymouri	48%	95%
A0A3Q8ICR8	Leishmania donovani	72%	100%
E9AGJ1	Leishmania infantum	72%	100%
E9AP29	Leishmania mexicana (strain MHOM/GT/2001/U1103)	70%	100%
Q4QGG0	Leishmania major	75%	100%