Extensin

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Extensin

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

E9AIL8_LEIBR

TriTrypDb:

LbrM.20.5860 , LBRM2903_200073800

Length:

278

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AIL8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AIL8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	105	107	PF00675	0.508
CLV_PCSK_KEX2_1	37	39	PF00082	0.678
CLV_PCSK_PC1ET2_1	37	39	PF00082	0.678
DEG_SPOP_SBC_1	143	147	PF00917	0.667
DOC_CKS1_1	123	128	PF01111	0.522
DOC_CKS1_1	150	155	PF01111	0.556
DOC_CYCLIN_yClb5_NLxxxL_5	7	13	PF00134	0.626
DOC_CYCLIN_yCln2_LP_2	78	84	PF00134	0.476
DOC_MAPK_gen_1	37	43	PF00069	0.672
DOC_PP2B_LxvP_1	111	114	PF13499	0.528
DOC_PP2B_LxvP_1	138	141	PF13499	0.516
DOC_PP2B_LxvP_1	91	94	PF13499	0.551
DOC_PP4_FxxP_1	49	52	PF00568	0.518
DOC_USP7_MATH_1	39	43	PF00917	0.670
DOC_WW_Pin1_4	122	127	PF00397	0.524
DOC_WW_Pin1_4	149	154	PF00397	0.553
DOC_WW_Pin1_4	16	21	PF00397	0.651
DOC_WW_Pin1_4	62	67	PF00397	0.677
LIG_14-3-3_CanoR_1	38	44	PF00244	0.670
LIG_BIR_II_1	1	5	PF00653	0.635
LIG_FHA_1	123	129	PF00498	0.519
LIG_FHA_2	58	64	PF00498	0.605
LIG_LIR_Gen_1	73	84	PF02991	0.631
LIG_LIR_Nem_3	215	220	PF02991	0.508
LIG_LIR_Nem_3	237	242	PF02991	0.501
LIG_LIR_Nem_3	73	79	PF02991	0.644
LIG_PCNA_yPIPBox_3	174	188	PF02747	0.650
LIG_PCNA_yPIPBox_3	6	17	PF02747	0.566
LIG_RPA_C_Insects	2	17	PF08784	0.631
LIG_SH2_CRK	76	80	PF00017	0.627
LIG_SH2_GRB2like	216	219	PF00017	0.510
LIG_SH2_NCK_1	76	80	PF00017	0.627
LIG_SH2_STAP1	225	229	PF00017	0.666
LIG_SH2_STAT3	180	183	PF00017	0.605
LIG_SH2_STAT3	207	210	PF00017	0.647
LIG_SH2_STAT3	243	246	PF00017	0.645
LIG_SH2_STAT5	180	183	PF00017	0.659
LIG_SH2_STAT5	220	223	PF00017	0.502
LIG_SH2_STAT5	250	253	PF00017	0.569
LIG_SH2_STAT5	76	79	PF00017	0.635
LIG_SH3_1	261	267	PF00018	0.670
LIG_SH3_2	260	265	PF14604	0.677
LIG_SH3_3	120	126	PF00018	0.611
LIG_SH3_3	128	134	PF00018	0.631
LIG_SH3_3	165	171	PF00018	0.646
LIG_SH3_3	208	214	PF00018	0.645
LIG_SH3_3	257	263	PF00018	0.670
LIG_SH3_3	33	39	PF00018	0.629
LIG_SH3_3	79	85	PF00018	0.536
LIG_SUMO_SIM_par_1	39	44	PF11976	0.603
LIG_TYR_ITIM	74	79	PF00017	0.639
LIG_WW_1	259	262	PF00397	0.673
LIG_WW_3	262	266	PF00397	0.678
MOD_CDK_SPK_2	151	156	PF00069	0.555
MOD_CDK_SPxxK_3	149	156	PF00069	0.554
MOD_CK1_1	2	8	PF00069	0.628
MOD_CK1_1	62	68	PF00069	0.686
MOD_CK2_1	57	63	PF00069	0.627
MOD_GlcNHglycan	1	4	PF01048	0.639
MOD_GlcNHglycan	221	224	PF01048	0.616
MOD_GlcNHglycan	227	230	PF01048	0.619
MOD_GSK3_1	139	146	PF00069	0.664
MOD_GSK3_1	219	226	PF00069	0.618
MOD_GSK3_1	246	253	PF00069	0.511
MOD_NEK2_1	219	224	PF00069	0.509
MOD_PIKK_1	272	278	PF00454	0.558
MOD_Plk_4	212	218	PF00069	0.508
MOD_Plk_4	238	244	PF00069	0.502
MOD_Plk_4	74	80	PF00069	0.491
MOD_ProDKin_1	122	128	PF00069	0.525
MOD_ProDKin_1	149	155	PF00069	0.554
MOD_ProDKin_1	16	22	PF00069	0.656
MOD_ProDKin_1	62	68	PF00069	0.672
TRG_ENDOCYTIC_2	216	219	PF00928	0.517
TRG_ENDOCYTIC_2	76	79	PF00928	0.635

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WW51	Leishmania donovani	68%	100%
A4HYZ9	Leishmania infantum	67%	100%
E9AUV1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	71%	99%
Q4QCN2	Leishmania major	68%	100%