LeishMANIAdb
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SUZ domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
SUZ domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
E9AIK1_LEIBR
TriTrypDb:
LbrM.20.5680 , LBRM2903_200071700 *
Length:
144

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AIK1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AIK1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 14 18 PF00656 0.504
CLV_NRD_NRD_1 100 102 PF00675 0.574
CLV_NRD_NRD_1 133 135 PF00675 0.630
CLV_NRD_NRD_1 39 41 PF00675 0.576
CLV_NRD_NRD_1 48 50 PF00675 0.659
CLV_PCSK_KEX2_1 100 102 PF00082 0.501
CLV_PCSK_KEX2_1 132 134 PF00082 0.629
CLV_PCSK_SKI1_1 70 74 PF00082 0.551
DOC_CYCLIN_RxL_1 67 77 PF00134 0.384
DOC_MAPK_gen_1 100 109 PF00069 0.537
DOC_PP2B_LxvP_1 119 122 PF13499 0.563
DOC_USP7_MATH_1 42 46 PF00917 0.687
DOC_WW_Pin1_4 110 115 PF00397 0.559
DOC_WW_Pin1_4 12 17 PF00397 0.704
DOC_WW_Pin1_4 18 23 PF00397 0.743
LIG_BIR_II_1 1 5 PF00653 0.748
LIG_FHA_1 121 127 PF00498 0.631
LIG_FHA_1 19 25 PF00498 0.717
LIG_FHA_1 30 36 PF00498 0.668
LIG_FHA_2 1 7 PF00498 0.511
LIG_FHA_2 12 18 PF00498 0.625
LIG_GBD_Chelix_1 68 76 PF00786 0.623
LIG_IRF3_LxIS_1 105 110 PF10401 0.522
LIG_SH3_3 59 65 PF00018 0.687
LIG_TRAF2_1 53 56 PF00917 0.731
LIG_TRAF2_1 77 80 PF00917 0.585
LIG_TRAF2_1 93 96 PF00917 0.604
LIG_UBA3_1 72 81 PF00899 0.643
LIG_WW_3 46 50 PF00397 0.693
MOD_CK1_1 110 116 PF00069 0.649
MOD_CK2_1 72 78 PF00069 0.546
MOD_GlcNHglycan 91 94 PF01048 0.657
MOD_N-GLC_1 107 112 PF02516 0.600
MOD_NEK2_1 107 112 PF00069 0.481
MOD_NEK2_1 11 16 PF00069 0.516
MOD_NEK2_1 72 77 PF00069 0.660
MOD_PIKK_1 91 97 PF00454 0.643
MOD_Plk_1 127 133 PF00069 0.559
MOD_Plk_4 120 126 PF00069 0.668
MOD_Plk_4 64 70 PF00069 0.603
MOD_ProDKin_1 110 116 PF00069 0.561
MOD_ProDKin_1 12 18 PF00069 0.699
MOD_SUMO_rev_2 54 59 PF00179 0.463
TRG_ER_diArg_1 131 134 PF00400 0.625
TRG_ER_diArg_1 99 101 PF00400 0.621
TRG_NLS_MonoCore_2 39 44 PF00514 0.588
TRG_NLS_MonoExtN_4 37 44 PF00514 0.580

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PD35 Leptomonas seymouri 71% 100%
A0A0S4ISW9 Bodo saltans 37% 73%
A0A1X0NW52 Trypanosomatidae 38% 77%
A0A3R7N8A8 Trypanosoma rangeli 38% 80%
A0A3S7WW97 Leishmania donovani 80% 99%
A4HYY7 Leishmania infantum 80% 99%
C9ZIJ6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 42% 86%
E9AUT3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 82% 99%
Q4QCQ0 Leishmania major 81% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS