Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania braziliensis

UniProt:

E9AIJ6_LEIBR

TriTrypDb:

LbrM.20.5630 , LBRM2903_200071100

Length:

315

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AIJ6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AIJ6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	69	73	PF00656	0.553
CLV_NRD_NRD_1	238	240	PF00675	0.545
CLV_PCSK_KEX2_1	118	120	PF00082	0.556
CLV_PCSK_KEX2_1	129	131	PF00082	0.426
CLV_PCSK_KEX2_1	238	240	PF00082	0.545
CLV_PCSK_PC1ET2_1	118	120	PF00082	0.441
CLV_PCSK_PC1ET2_1	129	131	PF00082	0.400
CLV_PCSK_PC7_1	234	240	PF00082	0.539
CLV_PCSK_SKI1_1	118	122	PF00082	0.437
DEG_Nend_Nbox_1	1	3	PF02207	0.420
DEG_SPOP_SBC_1	153	157	PF00917	0.515
DOC_CYCLIN_RxL_1	234	244	PF00134	0.540
DOC_USP7_MATH_1	153	157	PF00917	0.515
DOC_USP7_MATH_1	170	174	PF00917	0.632
DOC_USP7_MATH_1	182	186	PF00917	0.604
DOC_USP7_MATH_1	196	200	PF00917	0.568
DOC_USP7_MATH_1	202	206	PF00917	0.603
DOC_USP7_MATH_1	299	303	PF00917	0.359
DOC_USP7_MATH_1	76	80	PF00917	0.719
DOC_USP7_MATH_1	92	96	PF00917	0.495
DOC_USP7_MATH_1	99	103	PF00917	0.555
DOC_USP7_UBL2_3	177	181	PF12436	0.563
DOC_WW_Pin1_4	149	154	PF00397	0.627
DOC_WW_Pin1_4	158	163	PF00397	0.515
DOC_WW_Pin1_4	187	192	PF00397	0.691
DOC_WW_Pin1_4	194	199	PF00397	0.609
DOC_WW_Pin1_4	262	267	PF00397	0.647
LIG_14-3-3_CanoR_1	119	127	PF00244	0.380
LIG_14-3-3_CanoR_1	228	234	PF00244	0.392
LIG_14-3-3_CanoR_1	298	308	PF00244	0.362
LIG_14-3-3_CanoR_1	63	71	PF00244	0.544
LIG_APCC_ABBA_1	258	263	PF00400	0.529
LIG_FHA_1	126	132	PF00498	0.534
LIG_FHA_1	16	22	PF00498	0.553
LIG_FHA_1	213	219	PF00498	0.544
LIG_FHA_1	85	91	PF00498	0.520
LIG_FHA_1	98	104	PF00498	0.402
LIG_FHA_2	167	173	PF00498	0.691
LIG_FHA_2	201	207	PF00498	0.660
LIG_FHA_2	230	236	PF00498	0.379
LIG_FHA_2	44	50	PF00498	0.425
LIG_LIR_Gen_1	224	233	PF02991	0.399
LIG_LIR_Nem_3	224	229	PF02991	0.411
LIG_NRBOX	254	260	PF00104	0.400
LIG_Pex14_1	35	39	PF04695	0.559
LIG_SH2_STAT3	306	309	PF00017	0.519
LIG_SH2_STAT5	132	135	PF00017	0.378
LIG_SH3_3	192	198	PF00018	0.652
LIG_SUMO_SIM_anti_2	267	273	PF11976	0.576
MOD_CDK_SPxK_1	187	193	PF00069	0.584
MOD_CK1_1	152	158	PF00069	0.668
MOD_CK1_1	175	181	PF00069	0.572
MOD_CK1_1	185	191	PF00069	0.608
MOD_CK1_1	212	218	PF00069	0.712
MOD_CK1_1	264	270	PF00069	0.659
MOD_CK1_1	84	90	PF00069	0.617
MOD_CK2_1	166	172	PF00069	0.705
MOD_CK2_1	200	206	PF00069	0.666
MOD_CK2_1	229	235	PF00069	0.501
MOD_CK2_1	43	49	PF00069	0.521
MOD_GlcNHglycan	156	159	PF01048	0.612
MOD_GlcNHglycan	172	175	PF01048	0.708
MOD_GlcNHglycan	184	187	PF01048	0.733
MOD_GlcNHglycan	198	201	PF01048	0.561
MOD_GlcNHglycan	266	269	PF01048	0.626
MOD_GlcNHglycan	66	69	PF01048	0.665
MOD_GlcNHglycan	94	97	PF01048	0.495
MOD_GSK3_1	149	156	PF00069	0.632
MOD_GSK3_1	166	173	PF00069	0.720
MOD_GSK3_1	182	189	PF00069	0.675
MOD_GSK3_1	194	201	PF00069	0.541
MOD_GSK3_1	58	65	PF00069	0.664
MOD_GSK3_1	99	106	PF00069	0.440
MOD_NEK2_1	229	234	PF00069	0.600
MOD_NEK2_1	66	71	PF00069	0.596
MOD_NEK2_1	97	102	PF00069	0.445
MOD_PIKK_1	15	21	PF00454	0.556
MOD_PIKK_1	22	28	PF00454	0.499
MOD_PIKK_1	97	103	PF00454	0.443
MOD_PKA_1	118	124	PF00069	0.392
MOD_PKA_2	118	124	PF00069	0.392
MOD_PKA_2	229	235	PF00069	0.549
MOD_PKA_2	261	267	PF00069	0.609
MOD_PKA_2	299	305	PF00069	0.362
MOD_PKA_2	62	68	PF00069	0.580
MOD_Plk_1	134	140	PF00069	0.628
MOD_Plk_4	76	82	PF00069	0.629
MOD_ProDKin_1	149	155	PF00069	0.633
MOD_ProDKin_1	158	164	PF00069	0.517
MOD_ProDKin_1	187	193	PF00069	0.693
MOD_ProDKin_1	194	200	PF00069	0.610
MOD_ProDKin_1	262	268	PF00069	0.645
MOD_SUMO_rev_2	110	120	PF00179	0.407
MOD_SUMO_rev_2	52	61	PF00179	0.571
TRG_ENDOCYTIC_2	39	42	PF00928	0.548
TRG_ER_diArg_1	238	240	PF00400	0.545
TRG_ER_diArg_1	298	301	PF00400	0.549
TRG_Pf-PMV_PEXEL_1	111	116	PF00026	0.572

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7WW39	Leishmania donovani	62%	70%
A4HYY2	Leishmania infantum	62%	70%
E9AUS8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	66%	70%
Q4QCQ5	Leishmania major	62%	100%