LeishMANIAdb
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Putative RNA-binding regulatory protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative RNA-binding regulatory protein
Gene product:
pumilio protein 9, putative
Species:
Leishmania braziliensis
UniProt:
E9AIJ4_LEIBR
TriTrypDb:
LbrM.20.5610 , LBRM2903_200070800
Length:
244

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AIJ4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AIJ4

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 2
GO:0003723 RNA binding 4 2
GO:0005488 binding 1 2
GO:0097159 organic cyclic compound binding 2 2
GO:1901363 heterocyclic compound binding 2 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 60 62 PF00675 0.549
CLV_PCSK_KEX2_1 101 103 PF00082 0.640
CLV_PCSK_KEX2_1 127 129 PF00082 0.739
CLV_PCSK_KEX2_1 60 62 PF00082 0.549
CLV_PCSK_PC1ET2_1 101 103 PF00082 0.640
CLV_PCSK_PC1ET2_1 127 129 PF00082 0.739
CLV_PCSK_SKI1_1 108 112 PF00082 0.629
CLV_PCSK_SKI1_1 219 223 PF00082 0.818
CLV_PCSK_SKI1_1 60 64 PF00082 0.549
DEG_APCC_DBOX_1 60 68 PF00400 0.588
DEG_Nend_UBRbox_2 1 3 PF02207 0.549
DOC_CYCLIN_RxL_1 57 66 PF00134 0.549
DOC_CYCLIN_yCln2_LP_2 176 182 PF00134 0.801
DOC_USP7_UBL2_3 119 123 PF12436 0.637
DOC_WW_Pin1_4 196 201 PF00397 0.831
DOC_WW_Pin1_4 222 227 PF00397 0.798
LIG_14-3-3_CanoR_1 18 26 PF00244 0.617
LIG_14-3-3_CanoR_1 187 196 PF00244 0.843
LIG_Actin_WH2_1 60 77 PF00022 0.599
LIG_AP2alpha_2 2 4 PF02296 0.549
LIG_BIR_III_2 163 167 PF00653 0.768
LIG_CaM_IQ_9 111 127 PF13499 0.645
LIG_EH1_1 84 92 PF00400 0.579
LIG_eIF4E_1 170 176 PF01652 0.747
LIG_LIR_Apic_2 199 204 PF02991 0.818
LIG_LIR_Nem_3 2 7 PF02991 0.549
LIG_LIR_Nem_3 79 85 PF02991 0.589
LIG_LIR_Nem_3 99 103 PF02991 0.277
LIG_SH2_CRK 223 227 PF00017 0.792
LIG_SH2_NCK_1 201 205 PF00017 0.820
LIG_SH2_STAT3 232 235 PF00017 0.764
LIG_SH2_STAT3 7 10 PF00017 0.549
LIG_SH2_STAT5 24 27 PF00017 0.621
LIG_SH3_3 126 132 PF00018 0.770
LIG_SH3_3 204 210 PF00018 0.812
LIG_SH3_3 65 71 PF00018 0.604
LIG_SH3_3 91 97 PF00018 0.623
LIG_UBA3_1 33 40 PF00899 0.549
MOD_CK1_1 16 22 PF00069 0.620
MOD_CK2_1 196 202 PF00069 0.830
MOD_GlcNHglycan 189 192 PF01048 0.845
MOD_GlcNHglycan 216 219 PF01048 0.811
MOD_GlcNHglycan 226 229 PF01048 0.592
MOD_GSK3_1 13 20 PF00069 0.549
MOD_NEK2_1 34 39 PF00069 0.549
MOD_PIKK_1 141 147 PF00454 0.881
MOD_PKA_2 17 23 PF00069 0.622
MOD_Plk_4 209 215 PF00069 0.805
MOD_ProDKin_1 196 202 PF00069 0.830
MOD_ProDKin_1 222 228 PF00069 0.793
MOD_SUMO_for_1 118 121 PF00179 0.635
TRG_DiLeu_BaEn_2 201 207 PF01217 0.819
TRG_ENDOCYTIC_2 82 85 PF00928 0.574
TRG_ER_diArg_1 106 109 PF00400 0.628
TRG_ER_diArg_1 59 61 PF00400 0.549
TRG_Pf-PMV_PEXEL_1 60 65 PF00026 0.594

Homologs

Protein Taxonomy Sequence identity Coverage
Q9C9R6 ARATH 34% 38%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS