LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Thioredoxin-like_fold domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Thioredoxin-like_fold domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania braziliensis
UniProt:
E9AII7_LEIBR
TriTrypDb:
LbrM.20.5540 , LBRM2903_200070300
Length:
389

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

E9AII7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AII7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 316 320 PF00656 0.463
CLV_C14_Caspase3-7 48 52 PF00656 0.667
CLV_C14_Caspase3-7 67 71 PF00656 0.662
CLV_NRD_NRD_1 24 26 PF00675 0.664
CLV_NRD_NRD_1 372 374 PF00675 0.406
CLV_PCSK_KEX2_1 113 115 PF00082 0.700
CLV_PCSK_KEX2_1 24 26 PF00082 0.577
CLV_PCSK_KEX2_1 285 287 PF00082 0.426
CLV_PCSK_KEX2_1 372 374 PF00082 0.406
CLV_PCSK_PC1ET2_1 113 115 PF00082 0.700
CLV_PCSK_PC1ET2_1 285 287 PF00082 0.426
CLV_PCSK_SKI1_1 254 258 PF00082 0.392
CLV_PCSK_SKI1_1 272 276 PF00082 0.340
DEG_APCC_DBOX_1 214 222 PF00400 0.464
DEG_Nend_UBRbox_1 1 4 PF02207 0.539
DOC_CDC14_PxL_1 335 343 PF14671 0.356
DOC_MAPK_DCC_7 333 343 PF00069 0.374
DOC_MAPK_gen_1 258 267 PF00069 0.364
DOC_MAPK_MEF2A_6 258 266 PF00069 0.366
DOC_MIT_MIM_1 255 264 PF04212 0.379
DOC_PP1_RVXF_1 270 277 PF00149 0.348
DOC_USP7_MATH_1 165 169 PF00917 0.496
DOC_USP7_MATH_1 17 21 PF00917 0.699
DOC_USP7_MATH_1 73 77 PF00917 0.633
DOC_USP7_MATH_1 82 86 PF00917 0.548
DOC_WW_Pin1_4 243 248 PF00397 0.410
DOC_WW_Pin1_4 285 290 PF00397 0.463
DOC_WW_Pin1_4 30 35 PF00397 0.655
LIG_14-3-3_CanoR_1 159 163 PF00244 0.605
LIG_14-3-3_CanoR_1 176 182 PF00244 0.327
LIG_14-3-3_CanoR_1 272 277 PF00244 0.458
LIG_14-3-3_CanoR_1 354 364 PF00244 0.364
LIG_BRCT_BRCA1_1 167 171 PF00533 0.441
LIG_BRCT_BRCA1_1 19 23 PF00533 0.638
LIG_BRCT_BRCA1_1 199 203 PF00533 0.575
LIG_BRCT_BRCA1_1 272 276 PF00533 0.340
LIG_BRCT_BRCA1_1 287 291 PF00533 0.354
LIG_BRCT_BRCA1_1 308 312 PF00533 0.436
LIG_BRCT_BRCA1_1 42 46 PF00533 0.648
LIG_FHA_1 140 146 PF00498 0.565
LIG_FHA_1 180 186 PF00498 0.469
LIG_FHA_1 345 351 PF00498 0.405
LIG_FHA_2 266 272 PF00498 0.360
LIG_FHA_2 314 320 PF00498 0.448
LIG_LIR_Apic_2 33 38 PF02991 0.498
LIG_LIR_Gen_1 168 179 PF02991 0.495
LIG_LIR_Gen_1 288 299 PF02991 0.351
LIG_LIR_Nem_3 168 174 PF02991 0.511
LIG_LIR_Nem_3 273 279 PF02991 0.487
LIG_LIR_Nem_3 288 294 PF02991 0.261
LIG_LIR_Nem_3 307 313 PF02991 0.288
LIG_NRBOX 260 266 PF00104 0.349
LIG_PCNA_yPIPBox_3 176 185 PF02747 0.475
LIG_SH2_STAP1 78 82 PF00017 0.665
LIG_SH2_STAT5 237 240 PF00017 0.375
LIG_SH2_STAT5 279 282 PF00017 0.422
LIG_SH3_3 192 198 PF00018 0.596
LIG_SH3_3 328 334 PF00018 0.412
LIG_SH3_3 55 61 PF00018 0.658
LIG_SUMO_SIM_par_1 292 297 PF11976 0.320
LIG_TRAF2_2 227 232 PF00917 0.529
MOD_CK1_1 106 112 PF00069 0.525
MOD_CK1_1 137 143 PF00069 0.628
MOD_CK1_1 18 24 PF00069 0.665
MOD_CK1_1 270 276 PF00069 0.352
MOD_CK1_1 322 328 PF00069 0.426
MOD_CK1_1 76 82 PF00069 0.710
MOD_CK2_1 265 271 PF00069 0.352
MOD_CK2_1 345 351 PF00069 0.402
MOD_GlcNHglycan 136 139 PF01048 0.662
MOD_GlcNHglycan 167 170 PF01048 0.516
MOD_GlcNHglycan 17 20 PF01048 0.706
MOD_GlcNHglycan 247 250 PF01048 0.409
MOD_GlcNHglycan 25 28 PF01048 0.761
MOD_GlcNHglycan 347 350 PF01048 0.447
MOD_GlcNHglycan 97 100 PF01048 0.703
MOD_GSK3_1 165 172 PF00069 0.549
MOD_N-GLC_1 344 349 PF02516 0.444
MOD_N-GLC_1 51 56 PF02516 0.645
MOD_NEK2_1 10 15 PF00069 0.674
MOD_NEK2_1 179 184 PF00069 0.428
MOD_NEK2_1 189 194 PF00069 0.516
MOD_NEK2_1 23 28 PF00069 0.647
MOD_NEK2_1 304 309 PF00069 0.375
MOD_NEK2_1 313 318 PF00069 0.337
MOD_NEK2_2 383 388 PF00069 0.452
MOD_NEK2_2 41 46 PF00069 0.647
MOD_PIKK_1 106 112 PF00454 0.675
MOD_PKA_2 158 164 PF00069 0.615
MOD_PKA_2 23 29 PF00069 0.687
MOD_Plk_1 169 175 PF00069 0.501
MOD_Plk_1 189 195 PF00069 0.500
MOD_Plk_1 270 276 PF00069 0.352
MOD_Plk_2-3 217 223 PF00069 0.389
MOD_Plk_4 272 278 PF00069 0.409
MOD_Plk_4 319 325 PF00069 0.350
MOD_Plk_4 383 389 PF00069 0.424
MOD_Plk_4 41 47 PF00069 0.677
MOD_Plk_4 73 79 PF00069 0.633
MOD_ProDKin_1 243 249 PF00069 0.413
MOD_ProDKin_1 285 291 PF00069 0.454
MOD_ProDKin_1 30 36 PF00069 0.655
MOD_SUMO_rev_2 213 221 PF00179 0.474
TRG_DiLeu_BaLyEn_6 180 185 PF01217 0.403
TRG_DiLeu_BaLyEn_6 337 342 PF01217 0.373
TRG_ENDOCYTIC_2 279 282 PF00928 0.280
TRG_ER_diArg_1 23 25 PF00400 0.581
TRG_ER_diArg_1 371 373 PF00400 0.378
TRG_ER_diArg_1 86 89 PF00400 0.640

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P7C6 Leptomonas seymouri 67% 93%
A0A1X0NWG2 Trypanosomatidae 55% 100%
A0A3S7WW26 Leishmania donovani 88% 93%
A4HYX5 Leishmania infantum 88% 93%
E9AUS2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 85% 91%
Q4QCR4 Leishmania major 90% 100%
V5B5H3 Trypanosoma cruzi 58% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS